Navigation Links
Rhode Island Hospital first in US to treat kidney tumor with new device using electrical pulses
Date:1/9/2009

PROVIDENCE, RI On Thursday, January 8, Rhode Island Hospital treated an inoperable kidney tumor using a new technology known as NanoKnife. Damian Dupuy, MD, director of ablation services at Rhode Island Hospital and a national pioneer in ablation treatment, performed the procedure -- the first time it has been used on a kidney tumor in the United States.

NanoKnife is an image-guided device that uses "irreversible electroporation (IRE) technology" -- pulses of electricity that selectively destroy tumor cells while sparing nearby nerves, blood vessels and other delicate structures within the body. While considered a form of ablation, it uses electricity rather than heat like other ablation techniques such as cryo-ablation, radiofrequency and microwave ablation.

The Food and Drug Administration has approved the device for general soft tissue ablation. It was first used in Australia for tumors in the lungs and lymph nodes, and has been used in a handful of other types of cases in the United States.

Dupuy, who is serving as an advisor on the IRE technology, used the new NanoKnife on a 70-year-old female with a kidney tumor. The patient is reported to be doing well. Dupuy says, "I'm excited about the continued advances in ablation technology that broaden the applications for patients with cancer. These new technologies are revolutionizing the way we are able to treat cancer, allowing us to minimize collateral damage to surrounding tissue while maximizing tumor kill."

The NanoKnife is performed under sedation, however, little to no post-operative pain has been associated with the treatment to date. Because it is minimally invasive, Dupuy also notes that the new technology offers additional treatment options to patients who have no other alternatives or who have not responded to other forms of cancer treatment.

Prior forms of ablation treatment have been very successful in treating tumors in the past, and continue to provide new avenues of treatment for patients. Cryoablation, radiofrequency (RFA) and microwave ablation (MWA) all use intense heat or cold that destroys cells. The destroyed material may actually stay in the body for some time. The electrical fields used in the new IRE cause defects in cell membranes. Those cells within the targeted tissue then die within six hours of treatment, while the critical structures surrounding the targeted site are preserved and can then assist the body in removing the dead cells.

Damian Dupuy, MD, is a pioneer in image-guided ablation for the treatment of solid tumors, including RFA, MWA, cryoablation and now IRE. First approved by the FDA in 1997, RFA is a minimally invasive technique that uses heat to destroy tissue. A number of hospitals around the country have adopted the technique, most often to destroy liver tumors.

Dupuy, who is also a professor of diagnostic imaging at the Warren Alpert Medical School of Brown University, has broadened the applications of image-guided ablative therapies to successfully combat lung, kidney, adrenal, thyroid and bone cancer. Since 1997 more than 2,000 patients have undergone image-guided ablation at Rhode Island Hospital, the largest use of this technique in treating malignancy in North America. Other newer techniques such as combination therapies of ablation and external beam radiation or internal radiation seeds have been pioneered by Dupuy at Rhode Island Hospital. He is now leading National Cancer Institute-funded trials in the use of ablation for the treatment of tumors, and has published over 150 publications and given over 90 invited presentations nationally and internationally in the field of imaging and minimally invasive cancer therapies.


'/>"/>

Contact: Nancy Cawley
ncawley@lifespan.org
Lifespan
Source:Eurekalert

Related medicine news :

1. Blue Cross & Blue Shield of Rhode Island and Care New England Reach Multiyear Agreement
2. Blue Cross & Blue Shield of Rhode Island and Care New England Reach Agreement to Extend Network Participation
3. Rhode Island Hospital study finds local retail meat safe from antibiotic-resistant organisms
4. New research from Rhode Island Hospital may help predict outcomes for stomach cancer patients
5. InterComponentWare Inc. and Memorial Hospital of Rhode Island Celebrate Milestone
6. New Rhode Island Hospital study shows inadequate diagnostic criteria for eating disorders
7. Dominion Diagnostics Supports Rhode Islands Toys for Tots Initiative at Its 2007 Holiday Celebration
8. Rhode Island Hospital to study driving ability of cognitively impaired elders
9. Rhodes Named Head of Health Plan Administration Company TCC
10. Rhode Island Hospital lands $11.1M grant from National Institutes of Health
11. Neurological Surgery, P.C. of Long Island, NY Announces the Addition of Pediatric Neurosurgeon, Elizabeth M. Trinidad, M.D.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) ... FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... Morris F. Collen, a pioneer in the field of medical informatics, this prestigious award ...
(Date:10/12/2017)... LOS ANGELES (PRWEB) , ... October 12, 2017 ... ... of Parsa Mohebi Hair Restoration, has recently contributed a medical article to the ... doctors, on cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as ...
(Date:10/12/2017)... ... , ... On Saturday, October 21, the Health & Wellness Center at Florida ... money for the American Heart Association Heart Walk. Teams of up to 10 people ... keep their treadmills moving for 5 hours. Treadmills will start at 7:00 p.m. on ...
(Date:10/12/2017)... ... 12, 2017 , ... In the United States, single-family home ... states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the average is ... low property-tax rates, which contributes to the relatively lower cost of living in ...
(Date:10/12/2017)... CHICAGO (PRWEB) , ... October ... ... innovator in life sciences content management, presents its enhanced Pepper Flow promotional ... Oct. 16 -18, 2017. Pepper Flow’s increased insight-driven capabilities help marketers streamline ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... , Oct. 12, 2017 AVACEN Medical , ... company with their  2017 New Product Innovation Award for ... extensive primary and secondary medical device market research by Frost ... its first-to-market OTC, drug-free pain relief product, the AVACEN 100, ... to treating fibromyalgia widespread pain. ...
(Date:10/11/2017)... , Oct. 11, 2017  True Health, ... has amplified its effort during National Breast Cancer ... hereditary cancer risks. ... Clinical Oncology calculated that more than 10 million ... inherited mutations in BRCA1 or BRCA2 and have not ...
(Date:10/5/2017)... Ill. , Oct. 5, 2017  In ... Association of Oral and Maxillofacial Surgeons (AAOMS) released ... opioids – to be used as a first-line ... pain. Recognizing ... the AAOMS White Paper "Opioid Prescribing: Acute and ...
Breaking Medicine Technology: