Navigation Links
Rhode Island Hospital first in US to treat kidney tumor with new device using electrical pulses
Date:1/9/2009

PROVIDENCE, RI On Thursday, January 8, Rhode Island Hospital treated an inoperable kidney tumor using a new technology known as NanoKnife. Damian Dupuy, MD, director of ablation services at Rhode Island Hospital and a national pioneer in ablation treatment, performed the procedure -- the first time it has been used on a kidney tumor in the United States.

NanoKnife is an image-guided device that uses "irreversible electroporation (IRE) technology" -- pulses of electricity that selectively destroy tumor cells while sparing nearby nerves, blood vessels and other delicate structures within the body. While considered a form of ablation, it uses electricity rather than heat like other ablation techniques such as cryo-ablation, radiofrequency and microwave ablation.

The Food and Drug Administration has approved the device for general soft tissue ablation. It was first used in Australia for tumors in the lungs and lymph nodes, and has been used in a handful of other types of cases in the United States.

Dupuy, who is serving as an advisor on the IRE technology, used the new NanoKnife on a 70-year-old female with a kidney tumor. The patient is reported to be doing well. Dupuy says, "I'm excited about the continued advances in ablation technology that broaden the applications for patients with cancer. These new technologies are revolutionizing the way we are able to treat cancer, allowing us to minimize collateral damage to surrounding tissue while maximizing tumor kill."

The NanoKnife is performed under sedation, however, little to no post-operative pain has been associated with the treatment to date. Because it is minimally invasive, Dupuy also notes that the new technology offers additional treatment options to patients who have no other alternatives or who have not responded to other forms of cancer treatment.

Prior forms of ablation treatment have been very successful in treating tumors in the past, and continue to provide new avenues of treatment for patients. Cryoablation, radiofrequency (RFA) and microwave ablation (MWA) all use intense heat or cold that destroys cells. The destroyed material may actually stay in the body for some time. The electrical fields used in the new IRE cause defects in cell membranes. Those cells within the targeted tissue then die within six hours of treatment, while the critical structures surrounding the targeted site are preserved and can then assist the body in removing the dead cells.

Damian Dupuy, MD, is a pioneer in image-guided ablation for the treatment of solid tumors, including RFA, MWA, cryoablation and now IRE. First approved by the FDA in 1997, RFA is a minimally invasive technique that uses heat to destroy tissue. A number of hospitals around the country have adopted the technique, most often to destroy liver tumors.

Dupuy, who is also a professor of diagnostic imaging at the Warren Alpert Medical School of Brown University, has broadened the applications of image-guided ablative therapies to successfully combat lung, kidney, adrenal, thyroid and bone cancer. Since 1997 more than 2,000 patients have undergone image-guided ablation at Rhode Island Hospital, the largest use of this technique in treating malignancy in North America. Other newer techniques such as combination therapies of ablation and external beam radiation or internal radiation seeds have been pioneered by Dupuy at Rhode Island Hospital. He is now leading National Cancer Institute-funded trials in the use of ablation for the treatment of tumors, and has published over 150 publications and given over 90 invited presentations nationally and internationally in the field of imaging and minimally invasive cancer therapies.


'/>"/>

Contact: Nancy Cawley
ncawley@lifespan.org
Lifespan
Source:Eurekalert

Related medicine news :

1. Blue Cross & Blue Shield of Rhode Island and Care New England Reach Multiyear Agreement
2. Blue Cross & Blue Shield of Rhode Island and Care New England Reach Agreement to Extend Network Participation
3. Rhode Island Hospital study finds local retail meat safe from antibiotic-resistant organisms
4. New research from Rhode Island Hospital may help predict outcomes for stomach cancer patients
5. InterComponentWare Inc. and Memorial Hospital of Rhode Island Celebrate Milestone
6. New Rhode Island Hospital study shows inadequate diagnostic criteria for eating disorders
7. Dominion Diagnostics Supports Rhode Islands Toys for Tots Initiative at Its 2007 Holiday Celebration
8. Rhode Island Hospital to study driving ability of cognitively impaired elders
9. Rhodes Named Head of Health Plan Administration Company TCC
10. Rhode Island Hospital lands $11.1M grant from National Institutes of Health
11. Neurological Surgery, P.C. of Long Island, NY Announces the Addition of Pediatric Neurosurgeon, Elizabeth M. Trinidad, M.D.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... Carolina (PRWEB) , ... June 26, 2016 , ... ... of a new product that was developed to enhance the health of felines. The ... centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American ... Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. ... including advance care planning, healthcare costs and patient and family engagement. , AIR ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand ... project," said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s ... within Final Cut Pro X . Simply select a ProHand generator and drag ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. ... from injury. Recently, he has implemented orthobiologic procedures as a method for treating ... one of the first doctors to perform the treatment. Orthobiologics are substances that ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... A ... procedures that most people are unfamiliar with. The article goes on to state that ... but also many of these less common operations such as calf and cheek reduction. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... CAMBRIDGE, Mass. , June 24, 2016 /PRNewswire/ ... the Spaulding Rehabilitation Network,s Dean Center for ... of Physical Medicine and Rehabilitation, MIT Hacking Medicine, ... Center for Innovation, today announced the five finalists ... Hackathon for Lyme disease.  More than 100 scientists, ...
(Date:6/24/2016)... -- Dehaier Medical Systems Ltd. (NASDAQ: DHRM ... sells medical devices and wearable sleep respiratory products in ... agreement with Hongyuan Supply Chain Management Co., Ltd. (hereinafter ... 2016, to develop Dehaier,s new Internet medical technology business. ... leverage Hongyuan Supply Chain,s sales platform to reach Dehaier,s ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ... company developing innovative inhaled drugs, announced today that it ... Russell Investments reconstituted its comprehensive set of U.S. ... "This is an important milestone for Pulmatrix," said ... increase shareholder awareness of our progress in developing drugs ...
Breaking Medicine Technology: