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Revolutionary New Treatment for Sciatica Advances in the Clinic
Date:10/27/2009

Chronic and severe sciatica causes widespread disability, and represents a significant unmet medical need. Localized administration of etanercept, a unique anti-inflammatory therapeutic, represents a revolutionary new approach for reducing nerve root inflammation. This off-label treatment method, invented by a Los Angeles physician, Edward Tobinick MD, has increasing scientific support, including new data from randomized, placebo-controlled studies.

Los Angeles, California (PRWEB) October 27, 2009 -- Favorable new data from Japan regarding the efficacy of local administration of the unique anti-inflammatory therapeutic, etanercept, for treatment of sciatica was presented at the just concluded American College of Rheumatology Annual meeting in Philadelphia(1). Chemical inflammation of spinal nerve roots is a major factor in sciatic pain. Chronic and severe sciatica causes widespread disability, and represents a significant unmet medical need. The new data from Japan joins an increasing body of scientific evidence suggesting the efficacy of localized administration of etanercept for this indication.

The Japanese study was conducted by Kume et. al. in Hiroshima, utilizing a form of local perispinal ("around the spine") administration called caudal epidural injection. Local perispinal and epidural administration of etanercept for treatment of sciatica was invented by Edward Tobinick MD, Director of the Institute for Neurological Research® (INR®), a private medical group, inc. in Los Angeles, nearly a decade ago(2). Dr. Tobinick published the first results of perispinal etanercept for sciatica and related forms of intervertebral disc-related pain in 2003, with further publicatio
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