Navigation Links
Revisiting the need to detect circulating tumor cells
Date:3/16/2010

PHILADELPHIA (March 16, 2010)One of the most dangerous characteristics of cancer is its ability to metastasize, or spread through the body. For this reason, oncologists have a major need for better tests to detect cells that break away from primary tumors to travel to other parts of the body. Effective identification of these cells, referred to as circulating tumor cells (CTC's), could help guide treatment and improve quality of life for many cancer patients. A commentary in the March 17 issue of the Journal of the American Medical Association assesses the existing technology available to detect these cells and points to the need for still more progress in this area.

"The topic of circulating tumor cells has become more and more important as our knowledge of cancer and, in particular, breast cancer has evolved and as the technology to detect these cells has improved," says Massimo Cristofanilli, M.D., F.A.C.P., chair of the department of medical oncology at Fox Chase Cancer Center and lead author of the commentary. "But even though progress has been made, we need even better capabilities to detect these cells, which can tell us so much about the course of a patient's cancer."

Currently there is only one standardized and validated test approved by the U.S. Food and Drug Administration for the detection of CTC's, called the CellSearchTM system. CellSearch is a simple blood test that captures and assesses CTC's to determine the prognosis of patients with metastatic breast, colorectal, or prostate cancer at any time. This test, however, is only able to count CTC's and therefore additional technologies are being explored to capture more cells, different populations of the cells, and the gene expression patterns of the cells.

"It's important for us to look at all of these technologies in a more critical way to see which technologies are best at distinguishing between cells that have simply been shed by the tumor and those that are, instead demonstrating more aggressive," says Cristofanilli.

Using technologies that complement one another may also help improve the process of detecting these cells and design more personalized therapies. "For example, with inflammatory breast cancer we know that one technology alone will not help in detecting these cells," says Cristofanilli. "This doesn't mean they aren't there, it just means we aren't able to see them. It's like using a cameraby using full color, rather than black and white, you're able to see more distinct details."


'/>"/>

Contact: Diana Quattrone
Diana.Quattrone@fccc.edu
215-728-7784
Fox Chase Cancer Center
Source:Eurekalert

Related medicine news :

1. Revisiting the anthrax attacks
2. Restrictions on Plasma From Female Donors May Need Revisiting
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Eye-staining technique offers early detection for dry eye syndrome
5. Scientists detect presence of marburg virus in african fruit bats
6. Insurance Impacts Laryngeal Cancer Detection
7. New technique detects specific chromosomal damage, may indicate lung cancer risk
8. Blood-flow detector software show promise in preventing brain damage
9. Purdue researchers develop technology to detect cancer by scanning surface veins
10. Novel virus detection identifies new viruses in study of respiratory infections and asthma attacks
11. Drug Detection Kits Manufactured By IDenta Corp. Shown During French Television Broadcast (at TF1) - Product Aids French Police In Bust of 600 Kilograms Of Cocaine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2017)... ... ... Infallible Characteristics of Christ”: a fascinating and entrancing novel exploring the gifts and ... author, Rev. Dr. Robert W. Thomas, the third of seven siblings. He was a ... pastor for over fifteen years. He is a graduate of N.C. College of Theology ...
(Date:1/22/2017)... Frisco, TX (PRWEB) , ... January 22, 2017 , ... ... and provide slow results. Often the results of a simple test will take days ... review. Any Lab Test Now offers customers direct access to their lab tests, bypassing ...
(Date:1/21/2017)... MALO, FRANCE (PRWEB) , ... January 21, 2017 , ... ... of the Indian Ocean, isolated from the rest of the world with ZANZIBAR SHOWER ... East Africa, Phytocéane used key ingredients, Virgin Coconut Oil and moisturizing vegetal coral to ...
(Date:1/21/2017)... ... January 21, 2017 , ... The Nobel Biocare™ dental implant ... media for its creos™ line of bone regenerative products. Specifically, the ... he utilizes creos™ allo.gain™ bone graft for a variety of bone reconstruction procedures. ...
(Date:1/20/2017)... ... 2017 , ... Doctor C LLC, a company based out of Arizona that ... continue the marketing and distribution of its product, The Right C. , The Right ... absorption than traditional vitamin C supplements. At the trade show, Doctor C had the ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... Research and Markets has announced the addition of the ... to their offering. ... This research service on the global pharmaceutical stability testing market ... of the key participants in the market. The ... 2020. The market is expected to grow at a CAGR of ...
(Date:1/20/2017)... January 20, 2017 ... an Nothilfe   Die internationale humanitäre Stadt soll ... zu schaffen   Seine Hoheit Scheich ... VAE sowie Herrscher von Dubai , ... der Hilfe (International Humanitarian City IHC) zu verdreifachen, um ...
(Date:1/19/2017)... , Jan. 19, 2017 The ... 233.7 billion by 2025, according to a new ... is anticipated to be predominantly driven by high ... into the large-scale production of new and therapeutically ... influx of drugs at an unprecedented rate into ...
Breaking Medicine Technology: