Navigation Links
Review offers insight on managing surgical patients who are taking new drugs to prevent blood clots
Date:4/28/2014

New oral anticoagulant drugs that treat and prevent clots offer a much-needed alternative to warfarin, which has been used for more than 6 decades and has serious shortcomings. A new article published in BJS (British Journal of Surgery) gives an overview of the major clinical trials and recommendations related to these new agents and will serve as a practical guide for their use in patients who require planned or emergency surgery.

Warfarin has been the drug of choice to control blood clots in a variety of patients, including people with certain types of irregular heartbeats, people with prosthetic heart valves, and people who have suffered heart attacks. Unfortunately, warfarin has serious side-effects, requires frequent monitoring to reduce the risk of bleeding, and has interactions with multiple drugs and foods. New oral anticoagulant drugsApixaban, Dabigatran, and Rivaroxaban offer safer alternatives to warfarin, but there are currently no markers for measuring activity levels of the drugs and there are no antidotes to reverse or neutralize their effects.

Aida Lai, MBChB, of the North Bristol NHS Trust in the UK, and her colleagues searched the medical literature and analysed studies published between January 2000 and January 2014 that reported on the use of new oral anticoagulant drugs. "As these drugs are still relatively new in the market, knowledge about how they work and their associated bleeding risks are still limited in the medical and surgical community," said Dr Lai. "Our review covers recommendation for the discontinuation of new oral anticoagulant drugs before surgical procedures and resuming of these drugs after procedures." The review also notes that because the drugs are eliminated by the kidneys, they require dose reductions dependent on a patient's kidney function. Also, new oral anticoagulants are not recommended in patients with severe liver dysfunction. And because the three drugs have somewhat different
'/>"/>

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
201-748-6358
Wiley
Source:Eurekalert

Page: 1 2

Related medicine news :

1. McCullers reviews influenza, bacterial superinfections in Nature Reviews Microbiology
2. Internists review progress, challenges and opportunities
3. Do patient decision support interventions lead to savings? A systematic review
4. CU-built software uses big data to battle forgetting with personalized content review
5. PowerSteering from Upland Software Earns High Marks in Review by GetApp
6. Vision Without Glasses: Review Released by ReviewsGod.com
7. Total Balance Men’s: Review Released for Xtend-Life’s Comprehensive Dietary Supplement for Men
8. Workout Finishers Review – How Workout Finishers Helps People To Get A Fit Shape – Vinaf.com
9. 14 Day Rapid Fat Loss Plan Review–How To Get Rid Of Fat With 14 Day Rapid Fat Loss – Vinaf.com
10. The Cleft Palate–craniofacial Journal Marks 50 Years of Research With an Ethical Review
11. Regenstrief and IU review finds lack of delirium screening in the emergency department
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2015)... (PRWEB) April 27, 2015 Covenant Care, ... nationwide, has rolled out its “Enhanced Dining” service with ... foods developed with input from residents, patients and families ... and the redesign of its dining rooms so that ... the quality of life for our residents is our ...
(Date:4/26/2015)... (PRWEB) April 26, 2015 The ... both inpatient and outpatient therapy facilities that provide physical, ... years to 2015, the industry has experienced revenue growth ... acceptance of the benefits of physical therapy services. The ... helped support industry revenue growth during the period because ...
(Date:4/26/2015)... Indiana Fiber Network, LLC (IFN), the leading Indiana ... Company has selected IFN as a fiber transport provider. ... Mutual Insurance Company states: “IFN’s broadband fiber solution created ... We were interested in building entrance and ... ensure we achieved both. ” , According ...
(Date:4/26/2015)... India Network Foundation, a non-profit organization in ... to the Asian Indian community in the United States ... than two decades. The India News Network Digest of ... the world with the latest news items from India, ... Law Forum Digest, edited and contributed by Sheela Murthy, ...
(Date:4/26/2015)... The grand celebration got off to a festive start with ... Deb then introduced Sandy Valentine, the wife of CCAR’s Executive ... his Walk for Recovery on the Appalachian Trail. ... gratitude to the volunteers via video. Board President Tom Kirk ... CCAR’s mission. Volunteer Manager Conrad Sienkiewicz read the names ...
Breaking Medicine News(10 mins):Health News:Covenant Care Rolls Out "Enhanced Dining" Offering Restaurant Style Experience To Residents, Patients & Families 2Health News:Physical Therapy Rehabilitation Centers in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Physical Therapy Rehabilitation Centers in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:Brotherhood Mutual Insurance Company Selects Indiana Fiber Network, LLC for Fiber Transport Service 2Health News:Brotherhood Mutual Insurance Company Selects Indiana Fiber Network, LLC for Fiber Transport Service 3Health News:North American Telugu Society Bestows Community Service Award to India Network Foundation for Its Generosity and Sponsor of Visitor Health Insurance to Indian Visitors 2Health News:North American Telugu Society Bestows Community Service Award to India Network Foundation for Its Generosity and Sponsor of Visitor Health Insurance to Indian Visitors 3Health News:The Connecticut Community for Addiction Recovery (CCAR) honors its volunteers during National Volunteer Recognition Week. 2
... , , BETHESDA, Md., Dec. ... of the Cystic Fibrosis Foundation, today announced its 20th anniversary ... community nationwide. , , The ... and a mission to improve access to specialty medications for ...
... GABLES, Fla., Dec. 17 In the wake of the ... takes its place in Washington, leading CEOs and other thought ... to address the financial crisis, along with energy demand, health ... The University of Miami Global Business Forum, presented ...
... time patient consent forms came back full circle to a ... they have become. The original purpose of the consent forms ... of common or serious risks associated with the procedure to ... as formal, legal documents plants a litigious relationship ...
... DES MOINES, Iowa, Dec. 17 Protocol Driven Healthcare, Inc. (PDHI) announced today ... the National Committee for Quality Assurance (NCQA), an independent nonprofit organization that assesses ... , , ... ConXus Steps consumer health tools (wellness programs) - HIP 2 ...
... care as your parents and loved ones prepare for your ... keep most of familiar traditions that helped define your family,s ... that things don,t quite look the same as they did ... holiday checklist from Home Instead Senior Care if you help ...
... available in German . , Chocolate, excitement ... headache for parents. They are also responsible for triggering migraines ... avoid triggers are just as important as getting the right ... Health Care (IQWiG) today stressed that parents and young people ...
Cached Medicine News:Health News:Cystic Fibrosis Services Pharmacy Celebrates 20th Anniversary 2Health News:Top CEOs and Other Executives Gather in Miami to Address Economic Crisis, Alternative Energy, Health Care and More 2Health News:Top CEOs and Other Executives Gather in Miami to Address Economic Crisis, Alternative Energy, Health Care and More 3Health News:Patient consent forms should educate not intimidate 2Health News:PDHI's Health Risk Appraisal and Consumer Health Tools Awarded NCQA HIP Certification 2Health News:Does Your Senior Need Help at Home? A Holiday Checklist for Anyone Caring for Seniors 2Health News:Does Your Senior Need Help at Home? A Holiday Checklist for Anyone Caring for Seniors 3Health News:Migraines: Help for a common problem in children and teenagers 2
(Date:4/24/2015)... -- Hospira, Inc. (NYSE: HSP ), ... spoke about the importance of extrapolation in bringing biosimilars ... annual European Biosimilars Group conference in London ... publication of a pivotal white paper titled, "Why ... biosimilars." Speaking at the EGA conference, ...
(Date:4/23/2015)... , April 24, 2015  AbbVie (NYSE: ABBV ... Administration (FDA) has accepted its New Drug Application (NDA) ... two direct-acting antiviral treatment of ombitasvir, paritaprevir, ritonavir (OBV/PTV/r), ... of adults with chronic genotype 4 (GT4) hepatitis C ... first all-oral, interferon-free therapy being evaluated by the FDA ...
(Date:4/23/2015)... 23, 2015 Once again, BeaconMedaes is meeting ... to patient safety. BeaconMedaes, priority is to ... disease. The next generation Zone Valve Box ... are now mounted in the assembly, allowing for ease ... ceiling tiles potentially releasing dust spores and other bacteria ...
Breaking Medicine Technology:Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 2Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 3Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 4Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 5Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 6Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 7U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 2U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 3U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 4U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 5U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 6U.S. FDA Grants Priority Review to AbbVie for Investigational, All-Oral, Interferon-Free Therapy for the Treatment of Genotype 4 Chronic Hepatitis C 7BeaconMedaes launches new Zone Valve Box Assembly 2
... The BIOM 3 (Binocular Indirect Ophthalmo-Microscope) incorporates ... microscope and enables a view of up to ... the BIOM 3 the eye may be rotated ... easily viewed. Even surgery through small pupils ...
... The Philips HeartStart Home Defibrillatorthe latest ... than 175,000 devices deployed, Philips is ... defibrillators on airplanes, and in airports, ... HeartStart Home Defibrillator is the first ...
... custom bars have a large body ... contacts (spaced 3 centimeters center-to-center) to ... repeated cleaning. Polarity indicators are molded ... handle fits our bar electrode styles. ...
... custom bars have a large body ... contacts (spaced 3 centimeters center-to-center) to ... repeated cleaning. Polarity indicators are molded ... handle fits our bar electrode styles. ...
Medicine Products: