Review of cervical cancer screening program shows effectiveness and room for i...( Women who do not undergo regular cer...),Health

Women who do not undergo regular cervical cancer screening tests are more likely to be diagnosed with the disease than those who do, according to an audit of the Swedish national cervical cancer screening program that will be published online April 29 in the Journal of the National Cancer Institute. Participation in screening reduces the risk for all types of cervical cancers in all ages. Better follow-up of the women who are screened could further reduce cervical cancer rates, the researchers concluded.

Cervical cancer screening programs reduce the incidence of disease, but the effectiveness of such programs varies among populations. Regular audits of screening programs are valuable because they provide insight into how a program works and how it might be improved.

In this nationwide case–control study, Bengt Andrae, M.D., and colleagues of the Gävle Hospital and the Karolinska Institute in Sweden compared the rates of cervical cancer diagnosis in women who had been screened and those who had not. Using data from the Swedish Cancer Registry and from the National Cervical Cancer Screening Registry, the researchers identified 1,230 cervical cancer patients who were diagnosed between 1999 and 2001, and 6,124 age-matched control subjects, from the population register, who had not been diagnosed with cervical cancer.

Women who had not had a Pap smear screening test within the recommended 3-year interval were 2.5 times as likely to be diagnosed with cervical cancer as women who had Pap tests regularly. These women were also nearly 5 times as likely to be diagnosed with advanced disease as those who were screened. Participation in screening reduced the risk for all types of cervical cancer and reduced the risk of women between twenty-three and thirty; these were both novel findings.

Screening did not completely protect women from cervical cancer diagnoses, however. Women who were screened within the recommended interval and
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