Navigation Links
Rett Syndrome Association of MA joins to explore treatment option

Cincinnati, (OH) Rett Syndrome Association of Massachusetts (RSAM) and are thrilled to announce today their renewed commitment to work together to defeat Rett syndrome. A generous $150,000 donation from RSAM will support a approved grant to Dr. Michela Fagiolini's project at the Boston Children's Hospital: "Assessing NMDA receptor (NMDAr) modulators to ameliorate cortical regression in Rett syndrome".

Rajat Shah, Chairman of the Board, commented, "Rett Syndrome Association of Massachusetts has been a strong partner of for many years now. We are grateful and honored to grow our partnership in this significant way and take our collaboration to the next level. It will allow us to be more effective in reaching our common goal, developing treatments for our children, faster."

The Fagiolini laboratory at Boston Children's Hospital will conduct a preclinical study in a Rett mouse model, testing two very promising modulators of the NMDA (N-methyl-D-aspartate) receptor. These receptors are important for learning and memory and are somewhat impaired in Rett syndrome. The study will target the NMDA receptor with two different drugs, FDA approved ketamine and a new inhibitor of the NMDA receptor GLYX-13. They will evaluate the safety, pharmacokinetic activity, and efficacy of each drug. If the drugs are deemed safe and efficacious as positive and robust outcomes in the preclinical study, they will ready a potential clinical trial design with the goal of moving the compounds quickly to human clinical studies and evaluate these NMDA receptor modulators as potential treatments in girls diagnosed with Rett syndrome.

Jane Joyce, on behalf of RSAM, said, "We are incredibly grateful to the RSAM 2014 Boston Marathon Team Rett runners. Not only did the runners endure months of training in preparation for the marathon, but they committed to raising significant funds for Rett syndrome research. Our team of 26 runners, which included parents, aunts, cousins and friends of girls with Rett syndrome, went above and beyond this year. We are so thankful for their dedication and support. RSAM is pleased to be able to fully-fund Dr. Fagiolini's promising line of science and to continue our relationship with "


Contact: Shannon Starkey-Taylor
International Rett Syndrome Foundation

Related medicine news :

1. Normal triglyceride levels in people of African descent may hinder diagnosis of metabolic syndrome
2. Study: Women not getting enough exercise; at risk of developing metabolic syndrome
3. Cedars-Sinai physician definitively links irritable bowel syndrome and bacteria in gut
4. Myelodysplastic syndrome treated with deferasirox shows beneficial iron reduction, Moffitt says
5. Broken heart syndrome protects the heart from adrenaline overload
6. Myelodysplastic Syndrome Linked to Abnormal Stem Cells
7. UTHealth, French researchers discover gene defect for new syndrome
8. Drug shown to improve memory in those with Down syndrome
9. Sports guidelines for long QT syndrome patients may be too strict, Mayo Clinic finds
10. Chronic vulvar pain related to irritable bowel syndrome, fibromyalgia and interstitial cystitis
11. Genetic Studies Give Clues to Tourette Syndrome, OCD
Post Your Comments:
Related Image:
Rett Syndrome Association of MA joins to explore treatment option
(Date:6/27/2016)... ... 27, 2016 , ... "FCPX editors can now reveal their media with growing ... said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color brings ... users can now reveal the media of their split screens with growing colorful panels. ...
(Date:6/27/2016)... ... June 27, 2016 , ... ePAY ... partnership with Connance, a healthcare industry leader providing predictive analytics to optimize ... combine to provide health systems, hospitals and ambulatory surgical centers with dramatic ...
(Date:6/27/2016)... ... 2016 , ... recently awarded their highest five-star rating to Best Buy ... in the United States and Canada wear eyeglasses. Once considered to be a purely ... make a fashion statement. Even celebrities use glasses as a way of creating an ...
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a ... and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is ... to some of the world’s leading providers of cereal and other breakfast foods. Its ...
(Date:6/26/2016)... ... , ... PawPaws brand pet supplements owned by Whole Health Supply ... health of felines. The formula is all-natural and is made from Chinese herbs that ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 27, 2016  VMS Rehab Systems, Inc. ( ... whatever measures required to build a strong and stable ... currently listed on the OTC Markets-pink current trading platform. ... CEO, "We are seeing an anomaly in market trading ... only by the Company, but shareholders and market players ...
(Date:6/24/2016)... Calif. , June 24, 2016  Global ... a biopharmaceutical company developing novel therapeutics for the ... needs, today announced the closing of its previously ... common stock, at the public offering price of ... the offering were offered by GBT. GBT estimates ...
(Date:6/24/2016)... The Academy of Managed Care Pharmacy (AMCP) ... would allow biopharmaceutical companies to more easily share health ... and coverage decisions, a move that addresses the growing ... The recommendations address restrictions in the sharing of ... label, a prohibition that hinders decision makers from accessing ...
Breaking Medicine Technology: