Navigation Links
Rett Syndrome Association of MA joins Rettsyndrome.org to explore treatment option
Date:8/6/2014

Cincinnati, (OH) Rett Syndrome Association of Massachusetts (RSAM) and Rettsyndrome.org are thrilled to announce today their renewed commitment to work together to defeat Rett syndrome. A generous $150,000 donation from RSAM will support a Rettsyndrome.org approved grant to Dr. Michela Fagiolini's project at the Boston Children's Hospital: "Assessing NMDA receptor (NMDAr) modulators to ameliorate cortical regression in Rett syndrome".

Rajat Shah, Rettsyndrome.org Chairman of the Board, commented, "Rett Syndrome Association of Massachusetts has been a strong partner of Rettsyndrome.org for many years now. We are grateful and honored to grow our partnership in this significant way and take our collaboration to the next level. It will allow us to be more effective in reaching our common goal, developing treatments for our children, faster."

The Fagiolini laboratory at Boston Children's Hospital will conduct a preclinical study in a Rett mouse model, testing two very promising modulators of the NMDA (N-methyl-D-aspartate) receptor. These receptors are important for learning and memory and are somewhat impaired in Rett syndrome. The study will target the NMDA receptor with two different drugs, FDA approved ketamine and a new inhibitor of the NMDA receptor GLYX-13. They will evaluate the safety, pharmacokinetic activity, and efficacy of each drug. If the drugs are deemed safe and efficacious as positive and robust outcomes in the preclinical study, they will ready a potential clinical trial design with the goal of moving the compounds quickly to human clinical studies and evaluate these NMDA receptor modulators as potential treatments in girls diagnosed with Rett syndrome.

Jane Joyce, on behalf of RSAM, said, "We are incredibly grateful to the RSAM 2014 Boston Marathon Team Rett runners. Not only did the runners endure months of training in preparation for the marathon, but they committed to raising significant funds for Rett syndrome research. Our team of 26 runners, which included parents, aunts, cousins and friends of girls with Rett syndrome, went above and beyond this year. We are so thankful for their dedication and support. RSAM is pleased to be able to fully-fund Dr. Fagiolini's promising line of science and to continue our relationship with Rettsyndrome.org. "


'/>"/>

Contact: Shannon Starkey-Taylor
sstaylor@rettsyndrome.org
International Rett Syndrome Foundation
Source:Eurekalert  

Related medicine news :

1. Normal triglyceride levels in people of African descent may hinder diagnosis of metabolic syndrome
2. Study: Women not getting enough exercise; at risk of developing metabolic syndrome
3. Cedars-Sinai physician definitively links irritable bowel syndrome and bacteria in gut
4. Myelodysplastic syndrome treated with deferasirox shows beneficial iron reduction, Moffitt says
5. Broken heart syndrome protects the heart from adrenaline overload
6. Myelodysplastic Syndrome Linked to Abnormal Stem Cells
7. UTHealth, French researchers discover gene defect for new syndrome
8. Drug shown to improve memory in those with Down syndrome
9. Sports guidelines for long QT syndrome patients may be too strict, Mayo Clinic finds
10. Chronic vulvar pain related to irritable bowel syndrome, fibromyalgia and interstitial cystitis
11. Genetic Studies Give Clues to Tourette Syndrome, OCD
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Rett Syndrome Association of MA joins Rettsyndrome.org to explore treatment option
(Date:8/23/2017)... ... August 23, 2017 , ... CEFEX, the Centre ... to the standards representing best practices in the retirement plan industry. The independent ... and helps to verify that NFP’s retirement division focuses on putting clients’ interests ...
(Date:8/23/2017)... Mesa, Arizona (PRWEB) , ... August 23, 2017 ... ... is in the top 20% of hospitals nationally that earned the designation of ... annual list. An overall rating of high performing indicates a hospital was significantly better ...
(Date:8/23/2017)... ... August 23, 2017 , ... TSC ... Awards® - for Risk Management Solution Innovations and Security Solution for Government Innovations. ... released in 2017 and its DHS SAFETY Act-designated enterprise security assessment approach. , ...
(Date:8/22/2017)... ... August 22, 2017 , ... The ... health is as simple as eating healthy foods. But this well-known piece of ... making insulin, or breaking apart carbohydrates—depends not only on properties of the food ...
(Date:8/22/2017)... ... ... Nurses at Apple Rehab Watch Hill , a nursing and rehabilitation ... in Closed Pulse Irrigation™ (CPI) for wound care. This qualifies Apple ... Medicare and Medicaid Services, to have a CPI machine that will provide better quality ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... , Aug. 2, 2017 Fenita ... Who as a Pinnacle Lifetime Professional in the ... Account Manager at Turing Pharmaceuticals, AG. Her skills ... and relationship building.                ... than 25 years of experience as a highly ...
(Date:8/2/2017)... , Aug. 2, 2017  Life Flight Network and PeaceHealth ... agreement improves patient care and operational efficiency for patients at ... , Cottage Grove , and ... transportation. PeaceHealth and Life Flight Network work collaboratively to move ... transport, or when a time sensitive emergency exists. ...
(Date:8/1/2017)...   CerSci Therapeutics , a non-opioid drug development ... has received notice from the National Institute on Drug ... that it has been awarded a Direct-to-Phase II Small ... 2017 with an additional $1,000,000 to follow in 2018. ... of their lead non-opioid drug candidate CT-044 to the ...
Breaking Medicine Technology: