Navigation Links
Rethinking body mass index (BMI) for assessing cancer risk
Date:11/7/2012

November 8, 2012 (Bronx, NY) A study by researchers at Albert Einstein College of Medicine of Yeshiva University suggests that body mass index (BMI)the most commonly used weight-for-height formula for estimating fatnessmay not be the best measure for estimating disease risk, and particularly the risk of certain types of cancer. The study was published today in the online edition of the American Journal of Epidemiology.

BMI is calculated by dividing a person's weight (in kilograms) by his or her height in meters squared, or W/H2. Most of the early studies that used the formula, starting roughly sixty years ago, were conducted among middle-aged men. BMI has become the most widely-used weight-for-height index in large population studies of children and adults, thanks mainly to its ease of calculation and the ready availability of weight and height data. Newer technologies have since been developed for measuring body fat, but they can be prohibitively expensive and time consuming.

A BMI between 18.5 and 24.9 is considered ideal; obesity is defined as a BMI of 30 or greater. According to the Centers for Disease Control and Prevention, the higher one's BMI, the greater the risk for a range of diseases, including heart disease, high blood pressure, type 2 diabetes and certain cancers.

"It has long been recognized that BMI is an imperfect indicator of body fat because weight does not distinguish between lean body mass (muscle, bones, blood, water) and fat mass," said lead author Geoffrey C. Kabat, Ph.D., senior epidemiologist in the department of epidemiology & population health at Einstein. "This means that two individuals can have the same BMI but can have very different percentage of body fat." Furthermore, when using weight and height data, a single BMI formula may not be appropriate for all populations and all diseases."

The goal of the current study was to determine whether alternative weight-for-height measures resulted in stronger associations with risk of specific cancers compared to BMI. Using weight and height data on nearly 90,000 Canadian women enrolled in the Canadian National Breast Screening Study, the researchers varied the BMI formula changing the value of x in W/Hx to see whether any of these variations on BMI better predicted the risk of 19 different cancers.

All values of x in W/Hx that showed significant associations with specific cancers were below the value of 2.0 (i.e., BMI) and included 0.8 for endometrial cancer, 1.3 for lung cancer in those who never smoked, and 1.7 for postmenopausal breast cancer.

While these findings need to be confirmed in other studies, they suggest that the optimal value of W/Hx may differ depending on the population studied as well as on the disease of interest, and that BMI may not be optimal for all purposes.


'/>"/>

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Related medicine news :

1. Childrens self-control is associated with their body mass index as adults
2. The Journal of Injury, Function and Rehabilitation to be covered in Reuters Indexing Database
3. Assessing the risk of heart attack and stroke among Hispanics
4. Assessing the cost of the Affordable Care Act and expanding Medicaid
5. Study examines use of a natural language processing tool for electronic health records in assessing colonoscopy quality
6. Assessing Olympic terrorism threats
7. New targeted therapy for advanced prostate cancer shows anti-tumor activity in clinical trials
8. Patients with aberrations in two genes respond better to drugs blocking a well-known cancer pathway
9. Heart Failure Patients May Be at Higher Risk for Cancer: Study
10. Higher dietary glycemic load linked to worse colon cancer survival
11. Starchy, high carbohydrate diet associated with recurrence of colon cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes ... a mock evacuation of the facility as part of a disaster drill on October ... Hose EMS and Shelton City Emergency Manager, as well as the Connecticut Long ...
(Date:10/13/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has released ... understood books in the Holy Scriptures, Revelation. The Book of Revelation paints a picture ... Many have tossed it off as mere rubbish, but Yisrayl Hawkins says that is ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance (FHC), an ... showcase a range of technology and learning solutions at the 68th Annual American ... to be held October 14–18, 2017 at the Mandalay Bay Resort in Las ...
(Date:10/12/2017)... , ... October 12, 2017 , ... The American College ... to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in ... , In honor of Morris F. Collen, a pioneer in the field of medical ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts ... Washington, D.C., for the 49th Congress of the International Society of Paediatric Oncology ... of the Center for Cancer and Blood Disorders at Children’s National, and ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... 25, 2017   Montrium , an industry ... today—from the IQPC Trial Master Files & Inspection ... that EastHORN Clinical Services has selected eTMF ... TMF management. EastHORN, a leading European contract research ... increase transparency to enable greater collaboration with sponsors, ...
(Date:9/23/2017)... 22, 2017 Janssen Biotech, Inc. (Janssen) announced ... from the U.S. Food and Drug Administration (FDA) for ... for the treatment of moderately to severely active rheumatoid ... data are needed to further evaluate the safety of ... RA. "We ...
(Date:9/22/2017)... 22, 2017 AVACEN Medical (AVACEN) announced that ... successfully helping those with the widespread pain associated with ... Amanda in Essex, England commented, ... hair, experiencing no sleep at all, tremendous pain, with ... cannot recommend [the AVACEN 100] enough, how this has ...
Breaking Medicine Technology: