Navigation Links
Results of the STEMI-RADIAL trial presented at TCT 2012
Date:10/26/2012

MIAMI, FL OCTOBER 26, 2012 A study found several benefits in using the radial artery in the arm as the entry point for angioplasty or percutaneous coronary intervention (PCI) compared to the femoral artery in the leg. Results of the STEMI-RADIAL trial were presented today at the 24th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation (CRF), TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.

Recent data have demonstrated better clinical outcomes in patients undergoing primary PCI by the radial approach compared to the femoral approach. However, the experience of operators with the radial approach in previous trials has been variable. In the STEMI-RADIAL trial, investigators examined the net clinical benefit of using the radial versus femoral approach in patients presenting within 12 hours of symptom onset of acute ST-elevation myocardial infarction (STEMI). All investigators were high-volume (>200 PCI/year) operators with significant experience in the radial approach (>80% cases/year).

STEMI-RADIAL was a randomized, national, multicenter, parallel group trial conducted in 707 patients at four high-volume centers. Patients eligible for both access sites without cardiogenic shock were randomized to the radial or femoral access approach. The primary endpoint was the cumulative incidence of major bleeding and vascular access site complications (requiring intervention) at 30 days. Secondary endpoints included major adverse cardiovascular events (MACE: death, reinfarction and stroke), technical success, access site failure, procedural and fluoroscopy times, contrast volume, intensive care stay and target lesion revascularization.

The primary endpoint of major bleeding or access site complications occurred in 7.2 percent of the femoral access patients and 1.4 percent of the radial access patients (p=0.0001). The rate of MACE at 30 days was 4.2 percent in the femoral access group, and 3.5 percent in the radial access group (p=0.7).

"In patients with STEMI undergoing PCI within 12 hours, the radial approach was associated with a significantly lower incidence of major bleeding and access site complications, resulting in a significantly better net clinical benefit," said lead investigator Ivo Bernat, MD, PhD. Dr Bernat is an Assistant Professor of Medicine at University Hospital Pilsen in the Czech Republic.

"Moreover, the radial approach reduced significantly ICU stays and contrast volume compared to the femoral approach. Results of this trial support the use of the radial approach in primary PCI in high volume centers as a first choice," Dr. Bernat said.

The results of the STEMI-RADIAL trial will be presented on Friday October 26, 2012 at 11:55 AM in the Main Arena (Hall D) of the Miami Beach Convention Center.


'/>"/>

Contact: Judy Romero
jromero@crf.org
Cardiovascular Research Foundation
Source:Eurekalert

Related medicine news :

1. Results of the XIMA trial presented at TCT 2012
2. Results of the AIDA STEMI MRI sub-study presented at TCT 2012
3. Results of the PC trial presented at TCT 2012
4. Results of the POSEIDON trial presented at TCT 2012
5. 1-year results of ADAPT-DES presented at TCT 2012
6. Comparison of Obesity Surgeries Turns Up Surprising Results
7. Results from study of Mead Johnsons Enfamil® Human Milk Fortifier Acidified Liquid published in Pediatrics
8. Missed Diagnoses in ICU Often Have Deadly Results: Review
9. Anti-clotting drugs yield similar results
10. Late-Night Cramming May Hurt School Test Results
11. New survey: Women want to SEE breast reconstruction results before cancer surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2016)... ... May 05, 2016 , ... ... ultraviolet light A (UV-A) for photosynthesis, researchers Juntian Xu and Kunshan Gao tested ... seaweeds. The pair observed that when photosynthetically active radiation (i.e. the white light ...
(Date:5/5/2016)... ... May 05, 2016 , ... United Benefit Advisors ... Benefits as the latest addition to its family of Partner Firms. Headquartered in ... compliance, wellness, human resources, and health care consumerism specialists. , “Partnering with UBA ...
(Date:5/5/2016)... ... May 05, 2016 , ... An essential ... U.S. states and certain Canadian provinces is now available from the International Association ... (WCRI). , The report, Workers’ Compensation Laws as of January 1, ...
(Date:5/5/2016)... ... , ... A recent survey by the Midwest Business Group on Health ... and use the free preventive care benefits available to them as part of the ... self-insured public and private employers, MBGH found that only 10% of large employers are ...
(Date:5/5/2016)... TX (PRWEB) , ... May 05, 2016 , ... Vitenas ... AIA/AAH Healthcare Design Awards, presented by the American Institute of Architects and the Academy ... designed by the renowned Perkins+Will and Harrell Architects, opened to patients in October of ...
Breaking Medicine News(10 mins):
(Date:5/5/2016)... May 5, 2016 Progra m m ... of Oxitec , s mosquito in ... by 96 %   Oxitec ... plan to fight wild Aedes aegypti, the dangerous mosquito that spreads ... island of Grand Cayman .  MRCU, a global leader in ...
(Date:5/5/2016)... 5, 2016 ... of the  "Europe Thrombocythemia Market and ... to their offering.       ... ,The latest research Europe Thrombocythemia Market ... provides comprehensive insights into Thrombocythemia pipeline ...
(Date:5/4/2016)... Holdings (NYSE: CODI ) ("CODI," "we," "our" ... businesses, announced today its consolidated operating results for the ... Quarter 2016 Highlights , Generated Cash Flow Available ... $13.6 million for the first quarter of 2016; ... first quarter of 2016; , Paid a first ...
Breaking Medicine Technology: