Navigation Links
Results of the STACCATO Trial reported at TCT 2011
Date:11/10/2011

SAN FRANCISCO, CA NOVEMBER 10, 2011 Researchers leading a clinical trial said that transapical transcatheter aortic valve implantation (a-TAVI) may be inferior to surgical aortic valve replacement (SAVR) in operable elderly patients. However results were only preliminary as the trial was carried out on 70 patients out of a planned 200 before it was terminated early for safety concerns. Results from the STACCATO trial were presented today at the 23rd annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation.

TAVI has become a treatment option for patients with aortic valve stenosis, who are not amenable or at high risk to SAVR. The goal of the STACCATO trial was to compare a-TAVI with SAVR in operable elderly patients.

Researchers planned a 1:1 randomization of 200 unselected operable AVS patients with no need for revascularization and aged ≥ 75 years. The primary endpoint was the composite of death, stroke and/or renal failure at 30 days. Two Danish university centers participated after more than 40 TAVI procedures had been performed with good results at each center.

After inclusion of 70 patients (34 apical TAVI, 36 SAVR), the study was terminated after advice from the Data Safety Monitoring Board, because of an excess of events in the apical TAVI group. Baseline characteristics were similar in the two groups. The primary endpoint was met in five TAVI patients (two deaths, two major strokes, and one case of renal failure) compared to one stroke in the SAVR group.

"In its present phase of development, transapical transcatheter aortic valve implantation may be inferior to surgical aortic valve replacement in operable elderly patients," said Leif Thuesen, MD, the lead investigator of the trial. Dr. Thuesen is from the Department of Cardiology at Aarhus University Hospital in Denmark.

Researchers noted that after study termination, these pro
'/>"/>

Contact: Judy Romero
jromero@crf.org
Cardiovascular Research Foundation
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Results of the DEB-AMI Trial reported at TCT 2011
2. Results of the RIFLE STEACS clinical trial reported at TCT 2011
3. Results of the PARTNER Trial Cohort B 2-year follow up presented at TCT 2011
4. Results of the PARTNER Trial Cohort A cost effectiveness analysis reported
5. Combination epigenetic therapy clinical trial results
6. Results of the PARIS registry Reported at TCT 2011
7. Results of the TRIGGER-PCI trial reported at TCT 2011
8. Results of rapid gene trial reported at TCT 2011
9. Results of the BRIDGE trial reported at TCT 2011
10. First results of Angiomax (bivalirudin) vs. heparin in transcatheter aortic valve interventions
11. Osteoarthritis results from inflammatory processes, not just wear and tear, Stanford study suggests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... City, NY (PRWEB) September 02, 2014 ... Brinkley, Office Manager at Gibson Orthopedics ... Woman of the Year. Ms. Brinkley is recognized ... administration. As the largest, most-recognized networking organization of ... and profession, the National Association of Professional Women ...
(Date:9/1/2014)... a well is drilled, fitted with a hand pump, ... for the first time? Half of them break down ... sufficient resources and training, these wells would be rendered ... North Carolina-Chapel Hill,s (UNC) Water Institute and Water and ... if local water communities collect fees for repairs and ...
(Date:9/1/2014)... UWDress.com, a well-known wedding dress manufacturer and retailer, ... bridesmaid dresses for its new and old clients. ... online category. What’s more, they are offered at very ... is specially launched to celebrate the coming of autumn. ... won great appreciation from worldwide clients. Now, the company ...
(Date:9/1/2014)... “Australia Hernia Repair Market Outlook to 2020? provides ... The report provides value, in millions of US dollars, ... within market segments –,     Synthetic Meshes ...     Composite Meshes and Biological Meshes. , Hernia ... of a hernia (a bulging of internal organs or ...
(Date:9/1/2014)... may be bad for your waistline. TV viewers ate ... excerpt from a Hollywood action film than those watching ... for helping Americans to gain weight because it encourages ... been on the medium and not the message. TV ... to eat more, including reading, listening to the radio ...
Breaking Medicine News(10 mins):Health News:National Association of Professional Women Announces Laura Brinkley, Manager, Gibson Orthopedics Pain Treatment & Cardiology Clinic, a 2014 Professional Woman of the Year 2Health News:The key to drilling wells with staying power in the developing world 2Health News:The key to drilling wells with staying power in the developing world 3Health News:2014 Lime Green Bridesmaid Dresses Offered At UWDress.com 2Health News:Australia Hernia Repair Market (Synthetic, Composite and Biological Meshes) Outlook to 2020 Report Available at MarketOptimizer.org 2Health News:Australia Hernia Repair Market (Synthetic, Composite and Biological Meshes) Outlook to 2020 Report Available at MarketOptimizer.org 3Health News:Australia Hernia Repair Market (Synthetic, Composite and Biological Meshes) Outlook to 2020 Report Available at MarketOptimizer.org 4Health News:Research letter: Viewers ate more while watching Hollywood action flick on TV 2
... you,re ready to drive again , , WEDNESDAY, Dec. 10 (HealthDay ... wheel again after orthopedic surgery or injury, but knowing when it,s ... , Orthopedic surgeons weigh in on the issue in the December ... , "Deciding when a patient can return to driving is ...
... (OTC Pink Sheets: SNDY ) is pleased to announce that ... by over 10% compared to the same time period for 2007. ... $28,509 for the same month last year. This marks the second ... of October. , , The Mammo ...
... Inc., a leading,provider of software and databases for systems ... Singapore Immunology Network (SIgN) has become a,certified GeneGo Center ... MetaCore, training and advanced support. SIgN COE will ... "We are excited ...
... Facilities , , NEW ... process, a proven commitment to clinical quality earned SigmaCare(R) ... Metropolitan Jewish Health System,s (Metropolitan) skilled nursing facilities. ... nationally recognized nonprofit organization, operates Metropolitan Jewish Geriatric Center, ...
... Pharma Services, Goodwill, , , ... NYSE: MDZ ), a leading provider of products and ... fiscal 2008 performance. , Based on preliminary information, MDS ... of $1,210 million to $1,220 million and adjusted EBITDA in the ...
... Care Insurance While They,re Still Healthy Enough to Qualify , ... If you,ve put off getting long term care insurance, ... new administration,s health plan? "I wouldn,t advise it," says Denise ... (LTCFP), one of the nation,s most experienced long term care ...
Cached Medicine News:Health News:Returning to the Road Tricky After Injury 2Health News:Solos Endoscopy, Inc. Increases Sales Revenue for October 2008 by Over 10% as Compared to Last Year 2Health News:A*STAR's Singapore Immunology Network Is the First GeneGo Center of Excellence in Asia 2Health News:Metropolitan Jewish Health System Awards Electronic Medical Records Contract to SigmaCare(R) 2Health News:Metropolitan Jewish Health System Awards Electronic Medical Records Contract to SigmaCare(R) 3Health News:MDS Provides Update on Fiscal 2008 Performance 2Health News:MDS Provides Update on Fiscal 2008 Performance 3Health News:MDS Provides Update on Fiscal 2008 Performance 4Health News:Obama Health Plan Not Likely to Embrace Long Term Care, Industry Leader Says 2
(Date:8/29/2014)... 2014  A Boston Scientific Corporation (NYSE: ... removability and preliminary long term stricture resolution of ... August issue of the peer-reviewed journal, Gastroenterology. ... being conducted in 11 countries and five continents, ... stents (FCSEMS) after extended indwell (i.e., up to ...
(Date:8/29/2014)... Medina Medical announced today that Mr. Engelson ... Board of Directors on August 18, 2014. Mr. Engelson ... experience, including over a decade of direct experience in ... Partner of the medical device incubator The Foundry, after ... start-ups. Mr. Engelson previously served as the Chief Financial ...
(Date:8/29/2014)... Aug. 29, 2014  BC Technical, the nation,s leading ... Medical Imaging, a leader in sales, service and installation ... allows BC Technical to continue to expand their resources ... and CT modalities. "We are committed ... Mark Alvarez , president and CEO of BC Technical. ...
Breaking Medicine Technology:Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 2Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 3Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 4Medina Medical Announces Erik T. Engelson Joins as Chief Executive Officer 2BC Technical Acquires Polaris Medical Imaging 2
... PDL BioPharma, Inc. (PDL, the Company) (NASDAQ: PDLI ... aggregate principal amount of its 3.75% Convertible Senior Notes due ... conversion rate will initially be 126.2985 shares of common stock ... conversion price of approximately $7.92 per share of common stock. ...
... May 10, 2011 Cardica, Inc. (Nasdaq: CRDC ... and nine months ended March 31, 2011. Cardica,s management will ... to discuss the financial results and provide an update on ... diligently to bring our first anticipated commercial microcutter device, the ...
Cached Medicine Technology:PDL BioPharma, Inc. Prices Offering of $135.0 Million of Convertible Senior Notes Due 2015 2PDL BioPharma, Inc. Prices Offering of $135.0 Million of Convertible Senior Notes Due 2015 3PDL BioPharma, Inc. Prices Offering of $135.0 Million of Convertible Senior Notes Due 2015 4Cardica Announces Fiscal 2011 Third Quarter Financial Results 2Cardica Announces Fiscal 2011 Third Quarter Financial Results 3Cardica Announces Fiscal 2011 Third Quarter Financial Results 4Cardica Announces Fiscal 2011 Third Quarter Financial Results 5Cardica Announces Fiscal 2011 Third Quarter Financial Results 6
... OMNIPAQUE is an X-ray contrast ... and children for: angiography, urography, ... computed tomography of the basal ... endoscopic retrograde cholangio (pancreato) graphy ...
... IMAGOPAQUE is a non-ionic monomeric contrast ... in adults and children. After a decade ... 3.5 million examinations, IMAGOPAQUE has proven to ... effort in hundreds of radiology departments.Results from ...
... The only MR contrast agent FDA-approved ... is a gadolinium based, IV contrast media ... and liver. OptiMARK has convenient packaging ... contrast, packaged for efficient, problem-free delivery. You ...
... a contrast medium for Magnetic Resonance Imaging ... apyrogenic solution for intravenous injection. In MRI, ... brain, spine and surrounding tissues resulting in ... lesions with abnormal vascularity or those thought ...
Medicine Products: