Navigation Links
Results of the PROFI study reported at TCT 2011
Date:11/11/2011

SAN FRANCISCO, CA NOVEMBER 11, 2011 Results from the PROFI study indicate that the use of a proximal balloon occlusion in carotid artery stenting lead to fewer cerebral ischemic lesions a predictor of stroke than with the use of a filter. Trial results were presented today at the 23rd annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation.

Previous randomized trials have revealed a higher rate of stroke following carotid artery stenting when compared to surgical removal of plaque from the carotid artery. One of the reasons for this may be that the use of filters in carotid artery stenting allows plaque particles to travel to the brain. PROFI is the first randomized trial comparing proximal balloon occlusion with filter protection in patients undergoing carotid artery stenting

In the PROFI (Prevention of Cerebral Embolization by PROximal Balloon Occlusion Compared to FIlter Protection During Carotid Artery Stenting) trial, 62 patients undergoing carotid artery stenting with cerebral embolic protection for a ≥ 60 % symptomatic or ≥ 80% asymptomatic internal carotid artery stenosis were randomly assigned to proximal balloon occlusion or filter protection. The primary endpoint was the incidence of new cerebral ischemic lesions as assessed by diffusion weighted magnetic resonance imaging (DW-MRI). Secondary endpoints were the number and volume of new ischemic lesions and major adverse cardiovascular and cerebral events (MACCE).

The incidence rate of new cerebral ischemic lesions was 87.1%in the filter group, and 45.2% in the balloon group. The mean number of new cerebral ischemic lesions was 3.5 in the filter group and 1.0 in the balloon group. There were no significant differences in MACCE at 30 days between the two groups.

"In this single center, randomized trial in patients undergoing carotid artery stenting, the incidence, number, an
'/>"/>

Contact: Judy Romero
jromero@crf.org
Cardiovascular Research Foundation
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Results of the EVOLVE trial reported at TCT 2011
2. Results of the REMEDEE trial reported at TCT 2011
3. Results of the NEXT clinical trial Reported at TCT 2011
4. Results of the PEPCAD-DES trial reported at TCT 2011
5. Results of the STACCATO Trial reported at TCT 2011
6. Results of the DEB-AMI Trial reported at TCT 2011
7. Results of the RIFLE STEACS clinical trial reported at TCT 2011
8. Results of the PARTNER Trial Cohort B 2-year follow up presented at TCT 2011
9. Results of the PARTNER Trial Cohort A cost effectiveness analysis reported
10. Combination epigenetic therapy clinical trial results
11. Results of the PARIS registry Reported at TCT 2011
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2015)... The Residential Senior Care Franchises ... years. The industry, which provides residential and personal-care services ... for themselves, has boomed on account of the aging ... seniors with memory impairment. As a result, IBISWorld expects ... 4.1% to $1.9 billion over the five years to ...
(Date:4/18/2015)... Carinsurancequotesinfo.com has released a new blog post explaining ... caused by a car accident. , Car insurance ... A policy can pay for car repairs and even ... carry appropriate coverage when they are driving. ... several important riders that offer extra coverage options. One ...
(Date:4/18/2015)... Carinsurancehints.com has released a new blog post explaining how ... protection against fire damage. , Clients can now find ... vehicle is set intentionally on fire. This type of damages ... other things. , It is possible to compare the ... http://www.carinsurancehints.com/ , in just a few minutes. Clients should ...
(Date:4/18/2015)... PITTSBURGH, PA (PRWEB) April 18, 2015 ... so I decided to create a healthful juice ... an inventor from Rosedale, Md. "It increases my ... overall healthy body." , He developed Tapp's Juice ... The juice helps to prevent physical and mental ...
(Date:4/18/2015)... (PRWEB) April 18, 2015 Insuranceautoquote.info has ... online auto insurance quotes . , Clients ... a single website. The online environment provides important advantages ... vehicles. , Drivers who do not have coverage ... rates during any season, day or hour. Many agencies ...
Breaking Medicine News(10 mins):Health News:Residential Senior Care Franchises in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Residential Senior Care Franchises in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:Auto Insurance Plans Can Cover Physical Injuries Caused By An Accident! 2Health News:Online Auto Insurance Quotes For Plans That Cover Fire Damages! 2Health News:Clients Can Review Car Insurance Quotes Online To Find Low Cost Offers! 2
... have poor functioning of a key heart measure may ... arteries.// ,The researchers looked specifically at how the ... the arteries, called endothelial functioning, affects the development of ... followed from childhood. Over the 21 years of the ...
... Prostate cancer is the most common cancer among men, affecting ... 220,000 new cases // of the disease are diagnosed every ... year. ,New research shows men who are diagnosed with ... a high risk of developing prostate cancer within one year. ...
... red wine each day could keep keep lung cancer away ... cancer and 187 patients requiring routine surgery between 1999 and ... early 60s. Patients were asked about their diet, smoking habits, ... each day. They were asked to specify if they drank ...
... New research shows that sleep disorders may be linked ... ADD ), // neuromuscular conditions, and psychiatric problems. ... patients with sleep apnea also had ADD. Results also ... insomnia. Further testing showed some of these patients also ...
... with uncontrolled asthma may be able to gain complete ... ,Researchers studied 3,416 patients with uncontrolled asthma. Some ... steroid for their asthma; some were on a low-dose ... steroid. Patients in all three subgroups were randomly assigned ...
... reduction surgery can successfully treat metabolic syndrome in most ... is a combination of conditions putting people at high ... is characterized by higher than normal blood sugar, high ... involved 645 patients who were treated for obesity with ...
Cached Medicine News:
(Date:4/17/2015)... Nonin Medical, a global leader in noninvasive medical monitoring, ... Steve Bucholz will retire May 1. Company founder ... Chief Executive Officer. In addition, Mr. Isaacson will continue ... transition to David Noel , Chief Financial Officer. ... to Nonin Medical,s growth," Mr. Isaacson said. "Under Steve,s ...
(Date:4/17/2015)... R.I , April 17, 2015 CVS ... a conference call on Friday, May 1, 2015, at ... its first quarter financial results. An audio ... through the Investor Relations portion of the CVS Health ... visit http://investors.cvshealth.com . This webcast will be archived ...
(Date:4/17/2015)... ASSESS shows   plasma circulating tumour DNA (ctDNA) ... tumour biopsy   IGNITE supports value of ... AstraZeneca today presented results from two key studies ... for epidermal growth factor receptor (EGFR) mutation status in newly ... clinical practice. [ 1 ] , ...
Breaking Medicine Technology:Nonin Medical's Philip Isaacson Expands CEO Role; President and COO Steve Bucholz to Retire May 1 2"Real World" Data Support Use of Blood Test for EGFR Mutation in Advanced NSCLC 2"Real World" Data Support Use of Blood Test for EGFR Mutation in Advanced NSCLC 3"Real World" Data Support Use of Blood Test for EGFR Mutation in Advanced NSCLC 4
... AUG. 2 Two major studies,published today in The ... pregnant women at risk for preterm delivery who can ... today. In one large multi-center trial led by ... whom had no prior history of preterm birth) who,received ...
... Population of Glioblastoma Patients Expected to Support ... Promising New Approach -, TUSTIN, Calif., Aug. 2 ... stage biopharmaceutical,company developing targeted monoclonal antibodies for the treatment ... the first,patient has been administered Cotara(R) in a new ...
Cached Medicine Technology:Progesterone Therapy and Preterm Birth: More Evidence Helps Identify Women Who Can Benefit 2Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India 2Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India 3Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India 4
... shaped teeth set the blade on a straight accurate ... very sharp, and the cut starts true, dancing is ... minimal force due to the sharp, smooth ground, hardened ... , ,The troughs between the teeth provide an ...
Pneumatic High-speed Drill, Throttleless, 90k Rpm, Microaire Connector....
The High Speed Drill handpiece is a well-balanced, high performance drill that provides high speed for,bone sculpting, along with power for difficult osteotomies. Must be used with the 6401-000 foot ...
The High Speed Drill handpiece is a well-balanced, high performance drill that provides high speed for,bone sculpting, along with power for difficult osteotomies. Also available in a throttleless mod...
Medicine Products: