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Results of the PARIS registry Reported at TCT 2011
Date:11/9/2011

DAPT - mostly due to surgery or medical procedures (67%)
  • 12% had discontinuation of therapy (recommended by physician)

    "Importantly, any non-adherence (aspirin or thienopyridine non-adherence was equally distributed) was associated with higher rates of both ischemic and bleeding events at 30 days including death, myocardial infarction, definite and/or probable stent thrombosis, target vessel revascularization, and bleeding (BARC≥3)," said Roxana Mehran, MD, the co-principal investigator of the study. Dr. Mehran is Professor of Medicine at Mount Sinai School of Medicine and Director of Interventional Cardiovascular Research and Clinical Trials at the Zena and Michael A. Wiener Cardiovascular Institute. She also serves as Chief Scientific Officer of the CRF Clinical Trials Center.

    "There was a six-fold increase in odds for definite or probable stent thrombosis associated with non-adherence compared to adherence to DAPT at 30 days. The two year data will be more definitive and should be able to link the patterns of non-adherence with important clinical events," Dr. Mehran said.


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  • Contact: Judy Romero
    jromero@crf.org
    Cardiovascular Research Foundation
    Source:Eurekalert

    Page: 1 2

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