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Results of phase III study on Labopharm's novel antidepressant published in Psychiatry (Edgemont) Journal
Date:5/19/2009

sfunction in both groups.

The authors conclude that Labopharm's trazodone formulation, at the recommended daily dosage of 300 mg, appeared to be an appropriate monotherapy for patients with MDD.

Poster of Phase III Study to Appear at Scientific Meeting in Florida

Labopharm will present a poster discussing the results of the Phase III clinical trial of its novel trazodone formulation at the 49th Meeting of the New Clinical Drug Evaluation Unit (NCDEU) of the National Institute of Mental Health to be held from June 29 to July 2, 2009. The poster, entitled Once-Daily Trazodone in Major Depressive Disorder: Double-Blind, Placebo-Controlled Study, concludes Labopharm's trazodone formulation is an effective and well-tolerated treatment for MDD patients, which improves quality of sleep.

About Labopharm's Novel Antidepressant

Labopharm's novel trazodone formulation is currently under regulatory review in the United States by the Food and Drug Administration (FDA). The action date under the Prescription Drug User Fee Act (PDUFA) is July 18, 2009.

About Labopharm Inc.

Labopharm is an emerging leader in optimizing the performance of existing small molecule drugs using its proprietary controlled-release technologies. The Company's lead product, a unique once-daily formulation of tramadol, is now available in 17 countries around the world, including the U.S., Canada, the United Kingdom, France, Spain, Italy, Germany and Australia, among others. The company's second product, a novel formulation of trazodone for the treatment of major depressive disorder, is under regulatory review by the FDA. The Company also has a robust pipeline of follow-on products in both pre-clinical and clinical development. Labopharm's vision is to become an integrated, international, specialty pharmaceutical company with the capability to internally develop and commercialize its own products. For
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SOURCE Labopharm Inc.
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