Navigation Links
Restrictions on Plasma From Female Donors May Need Revisiting
Date:2/12/2010

In a surprise, heart patients who received male donors' plasma had worse outcomes, study found

FRIDAY, Feb. 12 (HealthDay News) -- The U.S. blood-banking industry discourages transfusing the blood product known as plasma from female donors because of a possible dangerous reaction in the recipients.

But now researchers have found that plasma that comes from females may actually have advantages.

Plasma is the fluid in blood in which blood cells are suspended. Researchers found that heart-surgery patients who received plasma from female donors did significantly better than those who got plasma from males. The plasma was donated before the restrictions went into place three years ago.

"Our findings raise the possibility of unanticipated effects of restricting female-donor plasma use," said Dr. Mark Stafford-Smith, a Duke University professor of anesthesiology and senior author of a study in the Feb. 11 issue of the Journal of Thoracic and Cardiovascular Surgery.

Females can still donate whole blood. But plasma has been considered problematic since plasma donated by females was linked to a lung injury related to transfusion. The cause appears to be related to antibodies that are more common in women who have been pregnant.

"We were very surprised by the results, because when we began the study, we expected to see data that supported the idea that female-donor plasma would be riskier," Stafford-Smith said. "In fact, we found just the opposite. At first, we thought we might have switched our data somehow, but careful re-examination confirmed that recipients of male-donor plasma had worse outcomes."

Patients who got plasma from female donors suffered lung dysfunction 5.9 percent of the time, compared to 10.8 percent of those who got plasma from male donors. They were also less likely to die within 30 days of surgery or be hospitalized longer than 10 days; however, the two groups had similar long-term survival rates.

More information

There's more on giving blood at the American Red Cross.



-- Randy Dotinga



SOURCE: Duke University, news release, Feb. 11, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Fingertip Formulary Restrictions(TM) Provides Unprecedented Access to Real- Time Managed Care Restrictions Data
2. Government restrictions on weight loss surgeries limit access for poor, underinsured patients
3. AGA Institute applauds delay of Aetna sedation restrictions
4. NCPA Statement on Sense of Congress Resolution Opposing FDA Restrictions on Estriol Usage
5. Nationwide Poll Shows 84% of Americans Favor Significant Restrictions on Abortion
6. Downgraded Tier Positions and Step Therapy Restrictions Have Stalled Exforges and Tekturnas Growth in The Hypertension Drug Market
7. Chindex International, Inc. Adopts Voluntary Executive Compensation Restrictions
8. University of Minnesotas Internationally Recognized Stem Cell Experts Available for Interviews on What Lifting the Federal Funding Restrictions Will Mean to Stem Cell Research and to Patients Who Stand to Benefit
9. Christopher & Dana Reeve Foundation Commends President Obamas Decision to Lift Federal Restrictions on Stem Cell Research
10. NIH May Ease Some, But Not All, Stem Cell Restrictions
11. Fixed Dosed Combination Agents and Novel Antihypertensives Are Expected to Face Tougher Formulary Restrictions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... Fla. (PRWEB) , ... October 12, 2017 , ... IsoComforter, ... therapy products, announced today the introduction of an innovative new design of the shoulder ... pad so you get maximum comfort while controlling your pain while using cold therapy. ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally ... care, have expanded their existing home health joint venture through an agreement, effective ... operating a joint venture home health company with Asante, delivering clinically integrated care, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, ... a medical article to the newly revamped Cosmetic Town journal section, ... hair transplant procedure known as Follicular Unit Extraction (FUE). , Dr. ...
(Date:10/12/2017)... ... ... Leading pediatric oncology experts at Children’s National Health System will ... the International Society of Paediatric Oncology (SIOP) Oct. 12-15. Chaired by Jeffrey ... Disorders at Children’s National, and Stephen P. Hunger, M.D., Chief of the Division ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... one of Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. ... awards program on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)...  Caris Life Sciences ® , a leading innovator ... precision medicine, today announced that St. Jude Medical Center,s ... (POA) as its 17 th member. Through participation ... Cancer Institute will help develop standards of care and ... making cancer treatment more precise and effective. ...
(Date:10/10/2017)... 10, 2017   West Pharmaceutical Services, Inc. ... injectable drug administration, today shared the results of a ... improving the intradermal administration of polio vaccines. The study ... in May 2017 by Dr. Ondrej Mach , ... Health Organization (WHO), and recently published in the journal ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017  According to the Centers for ... the end of October . PhysicianOne Urgent Care is helping communities across ... Westchester, NY , by offering no-cost* flu shots through the ... as mandated by certain health insurance regulations. ... The best time to get a flu shot is by the ...
Breaking Medicine Technology: