Navigation Links
Restrictions on Plasma From Female Donors May Need Revisiting
Date:2/12/2010

In a surprise, heart patients who received male donors' plasma had worse outcomes, study found

FRIDAY, Feb. 12 (HealthDay News) -- The U.S. blood-banking industry discourages transfusing the blood product known as plasma from female donors because of a possible dangerous reaction in the recipients.

But now researchers have found that plasma that comes from females may actually have advantages.

Plasma is the fluid in blood in which blood cells are suspended. Researchers found that heart-surgery patients who received plasma from female donors did significantly better than those who got plasma from males. The plasma was donated before the restrictions went into place three years ago.

"Our findings raise the possibility of unanticipated effects of restricting female-donor plasma use," said Dr. Mark Stafford-Smith, a Duke University professor of anesthesiology and senior author of a study in the Feb. 11 issue of the Journal of Thoracic and Cardiovascular Surgery.

Females can still donate whole blood. But plasma has been considered problematic since plasma donated by females was linked to a lung injury related to transfusion. The cause appears to be related to antibodies that are more common in women who have been pregnant.

"We were very surprised by the results, because when we began the study, we expected to see data that supported the idea that female-donor plasma would be riskier," Stafford-Smith said. "In fact, we found just the opposite. At first, we thought we might have switched our data somehow, but careful re-examination confirmed that recipients of male-donor plasma had worse outcomes."

Patients who got plasma from female donors suffered lung dysfunction 5.9 percent of the time, compared to 10.8 percent of those who got plasma from male donors. They were also less likely to die within 30 days of surgery or be hospitalized longer than 10 days; however, the two groups had similar long-term survival rates.

More information

There's more on giving blood at the American Red Cross.



-- Randy Dotinga



SOURCE: Duke University, news release, Feb. 11, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Fingertip Formulary Restrictions(TM) Provides Unprecedented Access to Real- Time Managed Care Restrictions Data
2. Government restrictions on weight loss surgeries limit access for poor, underinsured patients
3. AGA Institute applauds delay of Aetna sedation restrictions
4. NCPA Statement on Sense of Congress Resolution Opposing FDA Restrictions on Estriol Usage
5. Nationwide Poll Shows 84% of Americans Favor Significant Restrictions on Abortion
6. Downgraded Tier Positions and Step Therapy Restrictions Have Stalled Exforges and Tekturnas Growth in The Hypertension Drug Market
7. Chindex International, Inc. Adopts Voluntary Executive Compensation Restrictions
8. University of Minnesotas Internationally Recognized Stem Cell Experts Available for Interviews on What Lifting the Federal Funding Restrictions Will Mean to Stem Cell Research and to Patients Who Stand to Benefit
9. Christopher & Dana Reeve Foundation Commends President Obamas Decision to Lift Federal Restrictions on Stem Cell Research
10. NIH May Ease Some, But Not All, Stem Cell Restrictions
11. Fixed Dosed Combination Agents and Novel Antihypertensives Are Expected to Face Tougher Formulary Restrictions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... OR (PRWEB) , ... December 07, 2016 , ... Sharon ... Water, Global Climate Change and Your Health on Voice of America, declared on her ... to call attention to the fact that when these bullies attack leaders in corporate ...
(Date:12/7/2016)... , ... December 07, 2016 , ... Delete® - Tattoo ... Time For The Holiday Party Season. Save Up To 33% Off Botox® and Juvederm® ... is providing the Phoenix Valley with Delightful Deals on Botox® and Juvederm® ...
(Date:12/7/2016)... ... 2016 , ... The medical profession is well aware that heart attacks do ... analyzing heart attacks among 138,602 people recorded a 35% higher number of heart attacks ... agree of course–no time of year is a good time for a heart attack! ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... portable bioelectronic medicine device WellnessPro Plus for consumers and healthcare professionals to ... WellnessPro platform by expanding the treatment modalities available in a single device. ...
(Date:12/7/2016)... ... 07, 2016 , ... “Tomorrow Trump Goes To Washington”: a brief but ... presidency and to America. “Tomorrow Trump Goes To Washington” is the creation of published ... for this country. , Nancy attributes her patriotic nature to her WWII veteran father. ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... Dec. 7, 2016  Organovo Holdings, Inc. (NASDAQ: ... company focused on delivering scientific and medical breakthroughs ... Chairman and Chief Executive Officer Keith Murphy ... Wednesday, December 14, 2016 at 1:00 p.m. Eastern ... not yet familiar with the Company, an informational ...
(Date:12/7/2016)... FRANCISCO , December 7, 2016 ... expected to reach a value of USD 3.9 ... by Grand View Research, Inc. The growth of ... of donor and continuous technological advancements by the ... increasing continuously due to increasing donation, rising awareness ...
(Date:12/6/2016)... -- Diabetes & Obesity Drug Development Pipeline Review, 2016 ... is currently dominated by therapeutics indicated for type 1 ... and the majority of the pipeline, in terms of ... these indications. While products indicated for obesity do not ... large number of these products in the pipeline, with ...
Breaking Medicine Technology: