Navigation Links
Restrictions on Plasma From Female Donors May Need Revisiting
Date:2/12/2010

In a surprise, heart patients who received male donors' plasma had worse outcomes, study found

FRIDAY, Feb. 12 (HealthDay News) -- The U.S. blood-banking industry discourages transfusing the blood product known as plasma from female donors because of a possible dangerous reaction in the recipients.

But now researchers have found that plasma that comes from females may actually have advantages.

Plasma is the fluid in blood in which blood cells are suspended. Researchers found that heart-surgery patients who received plasma from female donors did significantly better than those who got plasma from males. The plasma was donated before the restrictions went into place three years ago.

"Our findings raise the possibility of unanticipated effects of restricting female-donor plasma use," said Dr. Mark Stafford-Smith, a Duke University professor of anesthesiology and senior author of a study in the Feb. 11 issue of the Journal of Thoracic and Cardiovascular Surgery.

Females can still donate whole blood. But plasma has been considered problematic since plasma donated by females was linked to a lung injury related to transfusion. The cause appears to be related to antibodies that are more common in women who have been pregnant.

"We were very surprised by the results, because when we began the study, we expected to see data that supported the idea that female-donor plasma would be riskier," Stafford-Smith said. "In fact, we found just the opposite. At first, we thought we might have switched our data somehow, but careful re-examination confirmed that recipients of male-donor plasma had worse outcomes."

Patients who got plasma from female donors suffered lung dysfunction 5.9 percent of the time, compared to 10.8 percent of those who got plasma from male donors. They were also less likely to die within 30 days of surgery or be hospitalized longer than 10 days; however, the two groups had similar long-term survival rates.

More information

There's more on giving blood at the American Red Cross.



-- Randy Dotinga



SOURCE: Duke University, news release, Feb. 11, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Fingertip Formulary Restrictions(TM) Provides Unprecedented Access to Real- Time Managed Care Restrictions Data
2. Government restrictions on weight loss surgeries limit access for poor, underinsured patients
3. AGA Institute applauds delay of Aetna sedation restrictions
4. NCPA Statement on Sense of Congress Resolution Opposing FDA Restrictions on Estriol Usage
5. Nationwide Poll Shows 84% of Americans Favor Significant Restrictions on Abortion
6. Downgraded Tier Positions and Step Therapy Restrictions Have Stalled Exforges and Tekturnas Growth in The Hypertension Drug Market
7. Chindex International, Inc. Adopts Voluntary Executive Compensation Restrictions
8. University of Minnesotas Internationally Recognized Stem Cell Experts Available for Interviews on What Lifting the Federal Funding Restrictions Will Mean to Stem Cell Research and to Patients Who Stand to Benefit
9. Christopher & Dana Reeve Foundation Commends President Obamas Decision to Lift Federal Restrictions on Stem Cell Research
10. NIH May Ease Some, But Not All, Stem Cell Restrictions
11. Fixed Dosed Combination Agents and Novel Antihypertensives Are Expected to Face Tougher Formulary Restrictions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal ... personalized through a fitness app. The fitness app plans to fix the two major problems ... offer a one size fits all type program , They don’t eliminate all ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery ... of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , ... for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , ... Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , ... our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
(Date:6/24/2016)... ... , ... Those who have experienced traumatic events may suffer from a complex ... as drug or alcohol abuse, as a coping mechanism. To avoid this pain and ... a traumatic event. , Trauma sufferers tend to feel a range of emotions, from ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)...  VMS Rehab Systems, Inc. ( www.vmsrehabsystemsinc.com ) reported ... required to build a strong and stable market for ... on the OTC Markets-pink current trading platform. ... are seeing an anomaly in market trading activities that ... the Company, but shareholders and market players as well. ...
(Date:6/24/2016)... 24, 2016  Collagen Matrix, Inc., ("Collagen Matrix") ... manufacturing of collagen and mineral based medical devices ... Bill Messer has joined the company ... leverage the growing portfolio of oral surgery, neurosurgery, ... Bill joins the Collagen Matrix executive team as ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... and Markets has announced the addition of the ... their offering. ... products and provides an updated review, including its applications ... covering the total market, which includes three main industries: ...
Breaking Medicine Technology: