Navigation Links
Restrictions on Plasma From Female Donors May Need Revisiting
Date:2/12/2010

In a surprise, heart patients who received male donors' plasma had worse outcomes, study found

FRIDAY, Feb. 12 (HealthDay News) -- The U.S. blood-banking industry discourages transfusing the blood product known as plasma from female donors because of a possible dangerous reaction in the recipients.

But now researchers have found that plasma that comes from females may actually have advantages.

Plasma is the fluid in blood in which blood cells are suspended. Researchers found that heart-surgery patients who received plasma from female donors did significantly better than those who got plasma from males. The plasma was donated before the restrictions went into place three years ago.

"Our findings raise the possibility of unanticipated effects of restricting female-donor plasma use," said Dr. Mark Stafford-Smith, a Duke University professor of anesthesiology and senior author of a study in the Feb. 11 issue of the Journal of Thoracic and Cardiovascular Surgery.

Females can still donate whole blood. But plasma has been considered problematic since plasma donated by females was linked to a lung injury related to transfusion. The cause appears to be related to antibodies that are more common in women who have been pregnant.

"We were very surprised by the results, because when we began the study, we expected to see data that supported the idea that female-donor plasma would be riskier," Stafford-Smith said. "In fact, we found just the opposite. At first, we thought we might have switched our data somehow, but careful re-examination confirmed that recipients of male-donor plasma had worse outcomes."

Patients who got plasma from female donors suffered lung dysfunction 5.9 percent of the time, compared to 10.8 percent of those who got plasma from male donors. They were also less likely to die within 30 days of surgery or be hospitalized longer than 10 days; however, the two groups had similar long-term survival rates.

More information

There's more on giving blood at the American Red Cross.



-- Randy Dotinga



SOURCE: Duke University, news release, Feb. 11, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Fingertip Formulary Restrictions(TM) Provides Unprecedented Access to Real- Time Managed Care Restrictions Data
2. Government restrictions on weight loss surgeries limit access for poor, underinsured patients
3. AGA Institute applauds delay of Aetna sedation restrictions
4. NCPA Statement on Sense of Congress Resolution Opposing FDA Restrictions on Estriol Usage
5. Nationwide Poll Shows 84% of Americans Favor Significant Restrictions on Abortion
6. Downgraded Tier Positions and Step Therapy Restrictions Have Stalled Exforges and Tekturnas Growth in The Hypertension Drug Market
7. Chindex International, Inc. Adopts Voluntary Executive Compensation Restrictions
8. University of Minnesotas Internationally Recognized Stem Cell Experts Available for Interviews on What Lifting the Federal Funding Restrictions Will Mean to Stem Cell Research and to Patients Who Stand to Benefit
9. Christopher & Dana Reeve Foundation Commends President Obamas Decision to Lift Federal Restrictions on Stem Cell Research
10. NIH May Ease Some, But Not All, Stem Cell Restrictions
11. Fixed Dosed Combination Agents and Novel Antihypertensives Are Expected to Face Tougher Formulary Restrictions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... ... ... who has struggled to quit smoking, a man who has struggled with hair loss – ... his problems – and he did. Now Nabat, a serial entrepreneur featured as the October ... to the world and better people's lives. His own experience with nicotine addiction led to ...
(Date:2/8/2016)... ... 2016 , ... Tingley Rubber Corporation , a leading ... range of unique and advantaged protective solutions to a growing and dynamic ... customer service and marketing support. A new distribution center in Brampton, Ontario will ...
(Date:2/8/2016)... , ... February 08, 2016 , ... ... enrichment program serving the greater Venice, FL area, has initiated a fundraiser for ... a car accident just four days after Christmas. To support this beautiful child ...
(Date:2/8/2016)... ... ... Remember the old saying “rub some dirt on it”? Perhaps you should try ... Clay” the health benefits of integrating clay into a daily diet are numerous, as ... motivational speaker, Perry A~ has since dedicated her life to learning about the benefits ...
(Date:2/8/2016)... ... February 08, 2016 , ... Discover the Rocky Mountain region’s ... booths and 700 companies. Attendees also get to see the most incredible gardens ... & Home Show , at the Colorado Convention Center - 700 14th St. Denver ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... SAN DIEGO , Feb. 8, 2016 /PRNewswire/--  ... have announced that advanced tissue-engineering services are now ... using a groundbreaking new three-dimensional (3D) bioprinting approach ... Regenova® 3D Bio Printer , a state-of-the-art robotic ... Applications has created a powerful pay-for-service bio-printing model ...
(Date:2/8/2016)... Feb. 8, 2016  Avista Pharma Solutions ("Avista Pharma") ... as Chief Financial Officer (CFO). Mr. Setzer is a ... experience in various roles within growing technology and life ... as the Executive Director of Finance at INC Research, ... Raleigh, NC . Previously, Mr. Setzer served as ...
(Date:2/8/2016)... 8, 2016 Velano Vascular, a medical technology ... patients and their practitioners, announced today that the company ... will use the proceeds from this financing, an extension ... January 2015, to support the development and commercialization of ... populations. Philadelphia , and ...
Breaking Medicine Technology: