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Response Genetics Reports Third Quarter 2007 Financial Results
Date:11/14/2007

for the comparable period in 2006 of $1.4, or $0.50 per share.

Cash and Cash Equivalents

Cash and cash equivalents at September 30, 2007 were $17.9 million compared to $3.0 million at September 30, 2006.

Clinical Development Highlights

Response Genetics To Make ERCC-1 Molecular Diagnostic Test Available in Q1 2008

On November 1, Response Genetics announced that it plans to make its test for Excision-Repair Cross-Complementing 1 (ERCC-1) gene expression for platin-based chemotherapy resistance available to selected institutions and clinical practice groups in the first quarter of 2008. The test will be offered only through Response Genetics' CLIA-certified laboratory in California. The initial launch will provide additional information about the clinical utility of ERCC-1 in the treatment of Non-Small Cell Lung Cancer (NSCLC); clinical practice activities such as sample acquisition, logistics, patient and physician communication; and the use of the test in normal clinical practice related to NSCLC. The Company plans to provide the appropriate financial resources to ensure that the initial market introduction is a success.

Previously, the Company announced the publication of promising results from a prospective study published in the July 1 issue of the Journal of Clinical Oncology. The data indicated that high expression of ERCC-1 in patients with advanced NSCLC predicts resistance to platin-based chemotherapy. These findings suggest that the measurement of ERCC-1 levels would play a role in individualizing treatment therapies for certain lung cancer patients. The multi-center, randomized study was designed to determine the overall response rate (complete plus partial responses) of patients with stage IIIb or IV NSCLC to cisplatin-based therapy by determining levels of the biomarker ERCC-1 mRNA in a paraffin-embedded tissue biopsy before administering treatment. The Company believes that this is the first prospective study using a
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SOURCE Response Genetics, Inc.
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