Navigation Links
Residual fetal cells in women may provide protection against breast cancer
Date:9/30/2007

SEATTLE Fetal cells that persist in a womans body long after pregnancy a common occurrence known in scientific circles as fetal microchimerism in some cases may reduce the womans risk of breast cancer, according to researchers at Fred Hutchinson Cancer Research Center. The findings, published in the Oct. 1 issue of Cancer Research, add to the Jekyll and Hyde characteristics of fetal microchimerism, or FMc, which has been found to be both detrimental and beneficial to womens health.

In this latest prospective study, scientists V.K. Gadi, M.D., Ph.D. and J. Lee Nelson, M.D., examined the blood of 82 women post-pregnancy, 35 of whom had had breast cancer. They looked for male DNA in the blood, presuming it was present due to a prior pregnancy. Fetal microchimerism (FMc) was found significantly more often in healthy women than women with a history of breast cancer, 43 percent versus 14 percent respectively. The scientists concluded that FMc may contribute to reduction of breast cancer based on the hypothesis that residual fetal cells may provide immune surveillance of malignant cells in the mother. They caution that further studies are needed to confirm the theory.

To our knowledge, the current results provide the first indication that FMc could impart a protective effect against breast cancer, Gadi said.

Prior research into FMc, some of it performed at the Hutchinson Center, indicates that while the presence of fetal cells in women may confer immune protection and promote cell repair, such cells also may be harbingers of some autoimmune diseases.

Two observations provided a rationale for the study hypothesis of the potential beneficial role of fetal cells, according to the authors. It is well established that women who have given birth have a lower risk of breast cancer. And, allogeneic (from another individual) stem-cell transplants are used to treat many types of blood cancers by replacing a diseased immune system with a healthy one


'/>"/>

Contact: Dean Forbes
dforbes@fhcrc.org
206-667-2896
Fred Hutchinson Cancer Research Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Anthrax drug doxycycline could stunt fetal growth
2. Fish Found To Improve Fetal Growth
3. Fetal Cell Transplant Found To Improve Movement In Patients With Parkinson’s Disease
4. Epidural can affect the fetal head position
5. Pomegranate juice to check fetal brain injury
6. Vitamin Supplements During Pregnancy to Boost Fetal Development
7. Worried About The Sensitive Skin Of Your 2 Year Old? Fetal Skin Cells To Offer Help
8. Using Eyes As The Line Of Reference For Fetal Brain Imaging
9. Simple Eye Movement Test For Early Detection Of Fetal Alcohol Spectrum Disorder
10. Genetic Disorders, Not Fetal Distress Increase Cerebral Palsy Risk
11. Fetal Development Face The Threat By Frequent Ultrasounds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... American adults who are beginning to research providers ... have a simpler way to connect with companies using ... some of the best life insurance rates available are ... promoted plans that included price data revealed to adults ... The term, guaranteed and modified plans that might be ...
(Date:8/28/2014)... 2014 ABC television stars will join ... Show of Strength Telethon airing Sunday, Aug. 31, 9/8c ... raise funds and awareness to help save and improve ... disease. , Viewers tuning into the 2014 telethon to ... and introductions from some of the network’s leading stars, ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 ... announced today a regional partnership designed to advance ... planning for competitive young athletes, scholastic athletes and ... partnership’s Strong Body & Mind Initiative will offer ... both the physical and mental dynamics involved in ...
(Date:8/28/2014)... CA (PRWEB) August 28, 2014 Gurnick ... the MRI Technology program is re-accredited for the 5 ... Magnetic Resonance Imaging Technologists (ARMRIT). , “We are ... are constantly improving our program to make sure we ... a lot of interest in MRI field nowadays and ...
(Date:8/28/2014)... A chronic problem in winemaking is "stuck fermentation," when ... alcohol and carbon dioxide prematurely shuts down, leaving the ... can spoil the wine. , A team of researchers ... a biochemical communication system behind this problem. Working ... can reproduce itself -- the system enables bacteria in ...
Breaking Medicine News(10 mins):Health News:Best Life Insurance Rates for 2014 Now Promoted at Insurer Website 2Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 2Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 3Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 4Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 2Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 3Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 4Health News:Gurnick Academy’s MRI Program Is Re-Accredited by ARMRIT for the 5 Years 2Health News:Prions can trigger 'stuck' wine fermentations, researchers find 2
... identification of genes that are responsible for diabetes has been ... study has been reported in the journal Nature. ... this study along with his team said that hereditary and ... their study could help in arriving at a genetic test ...
... risk of becoming infected with HIV, according to a ... Journal of Infectious Diseases (now online). ,It ... increase the risk of transmission and acquisition of HIV. ... per year worldwide, there are few robust data regarding ...
... to have died due to bird flu in Indonesia. This ... control of// the Indonesian health ministry. ,This is ... nation which is the highest for any country in the ... woman had contacted the H5N1 virus from a dead chicken ...
... Johns Hopkins Kimmel Cancer Center scientists have found a ... cells in their primitive state//. Unlocking the switches' code ... cells for transplant into patients with cancer and other ... control switches not at the gene level, but farther ...
... an AIDS drug and a heart medicine, and entered into ... more people can be treated. ,The negotiation panel ... first talks with US firm Abbott to discuss a price ... head of the department of disease control, said the firm ...
... have found that a substance similar to the active ... helps to control mobility// - and may offer a ... findings by Stanford University researchers, reported in the latest ... - one of the many chemicals used in the ...
Cached Medicine News:Health News:Vaginalis Increases the Risk of Becoming Infected With HIV 2Health News:Vaginalis Increases the Risk of Becoming Infected With HIV 3Health News:Master Switches Found for Adult Blood Stem Cells 2Health News:Thailand Backs Off Threat to Break Drug Patents 2Health News:Natural Brain Substance Linked to Parkinson's Symptoms 2
(Date:8/28/2014)... Colo. , Aug. 28, 2014   Venaxis, ... company focused on obtaining FDA clearance for and commercializing ... blood test for aiding in identifying children, adolescent, and ... at low risk for appendicitis, today announced it will ... Renshaw 16 th Annual Global Investment Conference being ...
(Date:8/28/2014)... 2014  Robotic surgery is creating buzz among ... the promise of improved outcomes and the potential ... surgical robots and market pressures to use this ... their robotic surgery training programs and ensure proper ... ECRI Institute ( www.ecri.org ), a nonprofit ...
(Date:8/28/2014)... , Aug. 28, 2014  Critical Process ... , today announces the expansion of their ... Critical Process Filtration now offers customers and potential ... fluids to filter failure analyses (even for competitor ... to their hallmark services of system benchmarking and ...
Breaking Medicine Technology:Venaxis to Present at September Investor Conferences 2Venaxis to Present at September Investor Conferences 3Surgical Robot Risk and Safety: ECRI Institute and Hartford Hospital Launch New Education Series 2Surgical Robot Risk and Safety: ECRI Institute and Hartford Hospital Launch New Education Series 3Surgical Robot Risk and Safety: ECRI Institute and Hartford Hospital Launch New Education Series 4Surgical Robot Risk and Safety: ECRI Institute and Hartford Hospital Launch New Education Series 5Critical Process Filtration, Inc. Announces Expanded Technical Services and Validation Support 2
... specifically for detection of recent-onset neovascular ("wet") ... maps and quantifies visual field defects consistent ... to the wet stage of the disease. ... for small visual field defects, the PreView ...
... a new functional test which exhibits 100% ... C Resistance caused by the Factor V ... commercially available methods, Pefakit APC-R FVL shows ... Lupus Anticoagulants, Elevated FVIII levels, Heparins or ...
Cable connections for 5 different adapters: Storz, ACMI, Pentax, Wolf and Olympus....
Lightweight PVC housing for easy transport, integrated handle. Easy lamp exchange....
Medicine Products: