Navigation Links
Researchers work to turn back the clock on bone-producing stem cells
Date:6/9/2011

AUGUSTA, Ga. Researchers want to turn back the clock on aging stem cells so they'll make better bone.

Bone-weakening osteoporosis results in a fracture every three seconds worldwide, according to the International Osteoporosis Foundation. The right nutrients resulting in the right signals could help aging stem cells act more youthful, producing stronger bones longer and reducing the death and disability associated with a frail framework, Georgia Health Sciences University researchers say.

While many headlines scream obesity, about one-third of Americans age 65 and older are malnourished it's called anorexia of aging which means their bone-producing stem cells probably lack the right nutrition and signals to stay healthy and focused on their job, said Dr. Carlos Isales, endocrinologist and Chief of GHSU's Program of Regenerative Medicine. And even sufficient calories may not provide the right nutrient mix for aging bones.

Ironically, the easiest thing for bone-producing mesenchymal stem cells to make is fat, which is often what they resort to with age and inadequate nutrients. "Fat is the cheapest thing for your body to make. If it has to make muscle, that consumes energy, if it has to make bone or blood cells, that takes energy, so fat is the default pathway," said Isales, principal investigator on a $6.3 million Program Project Grant from the National Institutes of Health designed to help keep stem cells on the right track.

He and colleagues Dr. Mark W. Hamrick, a bone biologist, and Dr. William D. Hill, a stem cell researcher, are taking on the problem from multiple angles.

They believe a key group of amino acids, found in good supply in protein, can help generate the signals stem cells need to keep producing bone. Bones cells have surface sensors for these nutrients and the researchers want to know how those change with age and which nutrients are their best activators.

These nutrients are in addition to
'/>"/>

Contact: Toni Baker
tbaker@georgiahealth.edu
706-721-4421
Georgia Health Sciences University
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. U-M researchers advocate national strategic approach to therapeutic cancer vaccines
2. Rhode Island and Miriam researchers say patient gender may influence nuclear stress test referrals
3. Researchers discover biochemical weakness of malaria parasite -- vaccine to be developed
4. Researchers find that inhibiting microRNAs may help prevent degenerative eye disorders
5. Calorie-burning brown fat is a potential obesity treatment, researchers say
6. City of Hope researchers to present rectal cancer, palliative care, benchmarking studies at ASCO
7. U of Alberta researchers hoping to stop heart disease in cancer patients before it starts
8. U of A researchers hope to stop heart
9. UofL researchers uncover mechanism in saliva production
10. UF researchers suggest cholera vaccination strategies for Zimbabwe
11. Researchers characterize epigenetic fingerprint of 1,628 people
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers work to turn back the clock on bone-producing stem cells
(Date:12/19/2014)... 19, 2014 Energy Textiles is ... now available. Celliant, the world’s leading responsive textile, ... pillowcases. , There are a number of benefits ... increased oxygenation and balanced body temperature; which can ... pain relief; enhanced athletic performance; and overall wellness. ...
(Date:12/19/2014)... 19, 2014 Silver Dollar City ... record -- for the first time ever, Silver Dollar City ... Guinness World Records 2015, listing the park’s wood coaster Outlaw ... In additional awards announced this week, Silver Dollar City is ... in the US,” USA Today’s 10Best awards for “Best Public ...
(Date:12/19/2014)... December 19, 2014 Eufaula, Oklahoma, located ... Lake Eufaula, the state’s largest lake with more than ... is home to a little more than 3,000 residents, ... on Saturday, the 6th of December. , Featuring Santa, ... through downtown Eufaula on Main Street. Narconon Arrowhead’s ...
(Date:12/19/2014)... An evening dress is perfect for any occasion and ... distinguished dresses retailer, has unveiled its new selection of evening ... great shopping platform. Customers can view more at ... has been accepted and praised by customers for many years. ... for clients. In order to expand its market share, the ...
(Date:12/19/2014)... The print component of Vision and Hearing is ... Toronto Star, with a circulation of approximately 230,433 copies ... is distributed nationally through a vast social media strategy ... partner outlets. To explore the digital version of the ... an exclusive interview with Mark DeMontis , sharing ...
Breaking Medicine News(10 mins):Health News:Energy Textiles Launches Celliant Revitalizing Bedsheets 2Health News:Silver Dollar City Nets New Titles: Guinness Book of World Records, Plus CNN Travel, USA Today & Fodor’s Top Places for Christmas Lights 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 3Health News:Attractive Evening Dresses Announced by Discount-Dress.com 2Health News:Mark DeMontis, Founder of Courage Canada, shares his passion for bringing hockey to those affected by blindness in Mediaplanet’s “Vision and Hearing” campaign 2
... investigators Lewis C. Cantley, PhD, and Cornelius P. Terhorst, PhD, ... American Association for the Advancement of Science. They are ... distinguished efforts to advance science, and will be honored during ... BIDMC,s Division of Signal Transduction and Director of the BIDMC ...
... This release is available in German . ... of recovery depending on disease stage. Experts hope that the ... is more helpful in the choice of the right treatment ... for Quality and Efficiency in Health Care (IQWiG) has now ...
... 2011 HIV-positive head and neck cancer patients respond ... rates as non-HIV-positive patients, despite prior reports to the ... of the International Journal of Radiation OncologyBiologyPhysics , ... Oncology (ASTRO). , Patients with HIV have a significantly ...
... The combined results of a genetic blood test and ... of healthy older adults, many of whom were destined ... John Woodard, Ph.D., associate ... and Sciences and Institute of Gerontology at Wayne State ...
... (Jan. 19, 2011) A new program designed to create ... Colorado has received a $3.9 million grant from the Colorado ... four-year program housed in the Department of Family Medicine at ... brings together local and national leaders from the mental health, ...
... Dotinga HealthDay Reporter , TUESDAY, Jan. 18 (HealthDay ... that aims to reveal the presence of Alzheimer,s disease, potentially ... early stages. Another study finds that blood tests could indicate ... there,s a catch: Alzheimer,s disease is not curable, and existing ...
Cached Medicine News:Health News:Malignant brain tumors: Benefit of PET and PET/CT in the detection of recurrences is not assessable 2Health News:HIV-positive head and neck cancer patients benefit from radiation therapy 2Health News:Wayne State University study predicts risk of memory loss in healthy, older adults 2Health News:New program targeting whole-person health care gets major grant 2Health News:Progress Reported in Predicting Alzheimer's 2
(Date:12/19/2014)... 18, 2014  Sage Analytics ( www.sageanalytics.com ), ... for the testing of marijuana potency and moisture ... Luminary™ Profiler, the industry,s first product suite capable ... cost-effective, portable unit. Designed from the ... the cannabis industry, the Luminary™ Profiler utilizes specially ...
(Date:12/19/2014)... , Dec. 18, 2014 Baptist Health Lexington is ... to receive full Atrial Fibrillation with Electrophysiology Services (EPS) ... Atrial fibrillation is the most common cardiac arrhythmia ... some cases can lead to stroke and possible death. More ... have atrial fibrillation and the numbers are rapidly ...
(Date:12/19/2014)... membrane market has witnessed robust development with the growth pace ... later starter. In 2012, the size of China ... the proportion worldwide soaring to 16.3%. It is projected that ... its growth rate by around 20% in the upcoming years ... RMB25 billion. An integrated membrane industrial system has ...
Breaking Medicine Technology:Sage Analytics Develops Breakthrough System for Potency Testing of Cannabis Products 2Baptist Health Lexington First in the Nation to Receive Atrial Fibrillation with EPS Accreditation 2Baptist Health Lexington First in the Nation to Receive Atrial Fibrillation with EPS Accreditation 3Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 3
... 2011 Nephros, Inc. (OTC Bulletin Board: NEPHD ... for therapeutic applications, infection control, and water purification, announced today ... December 31, 2010. 2010 Highlights ... prior year period Increased gross margin by 22% to ...
... Valeant Pharmaceuticals International, Inc. (NYSE: VRX ... a proposal to the Board of Directors of Cephalon, ... for $73.00 per share in cash.  The proposal, valued ... 29% over Cephalon,s 30-day trading average.  Valeant announced its ...
Cached Medicine Technology:Nephros Reports 2010 Fourth Quarter and Full Year Financial Results 2Nephros Reports 2010 Fourth Quarter and Full Year Financial Results 3Nephros Reports 2010 Fourth Quarter and Full Year Financial Results 4Nephros Reports 2010 Fourth Quarter and Full Year Financial Results 5Nephros Reports 2010 Fourth Quarter and Full Year Financial Results 6Nephros Reports 2010 Fourth Quarter and Full Year Financial Results 7Nephros Reports 2010 Fourth Quarter and Full Year Financial Results 8Nephros Reports 2010 Fourth Quarter and Full Year Financial Results 9Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 2Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 3Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 4Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 5Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 6Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 7Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 8Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 9Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 10Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 11Valeant Pharmaceuticals Proposes to Acquire Cephalon, Inc. for $73 Per Share in Cash 12
... The Albumin Cobalt Binding (ACB®) Test ... Ischemia Modified Albumin (IMA®) by measuring the ... patient serum sample. First identified in the ... albumin comes in contact with ischemic tissue ...
... Cobalt Binding (ACB®) Test is a clinical ... (IMA®) by measuring the cobalt binding capacity ... First identified in the early 1990s, IMA ... contact with ischemic tissue in the heart. ...
Inquire...
... Our ELISA products for autoimmune testing feature ... as well as specific reflex tests including ... Sm/RNP, SS-A (Ro), SS-B (La), Scl-70 and ... includes a full line of products for ...
Medicine Products: