Navigation Links
Researchers who helped millions with arthritis receive prestigious Janssen Award
Date:5/12/2008

Two British researchers who pioneered treatments which have helped millions of people with rheumatoid arthritis and other autoimmune diseases have been awarded the prestigious 2008 Dr. Paul Janssen Award for Biomedical Research, announced today.

Emeritus Professor Sir Ravinder Maini and Professor Marc Feldmann, who have been carrying out research together at Imperial College London since the 1980s, were selected for the $100K award by an international committee including Nobel Laureates and other world-renowned scientists.

Their research has led to the development of new drugs which tackle the inflammation and tissue destruction caused by rheumatoid arthritis and other diseases including ankylosing spondylitis, psoriatic arthritis, psoriasis, Crohns disease and ulcerative colitis.

The treatments they developed, now used by millions of people across the world, have proved effective in most patients, even those resistant to all previous treatments. They also protect the joints from further destruction.

Previous treatment options for rheumatoid arthritis left almost half of all patients with symptoms of continuing disease, deterioration of physical function and progressive joint damage.

The breakthrough came for Professors Maini and Feldmann when they discovered how autoimmune diseases such as arthritis cause the immune system to fight itself. Their work showed that the key lay in molecules responsible for cell communication, known as cytokines.

Cytokines are normally released by immune cells, to alert the immune system to initiate a protective counter-response against infections. Professors Maini and Feldmann discovered that in autoimmune diseases, cytokines are over-produced, with highly increased cytokine levels around otherwise healthy cells. This leads to the signs and symptoms of disease and in rheumatoid arthritis it explains the body's aggressive reaction in areas of arthritic inflammation around p
'/>"/>

Contact: Laura Gallagher
L.Gallagher@imperial.ac.uk
44-020-759-46702
Imperial College London
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Carnegie Mellon engineering researchers automate analysis of protein patterns
2. Health researchers in McGill network receive $35.5 million in CIHR funding
3. Hopkins researchers discover new link to schizophrenia
4. Researchers find gene location that gives rise to neuroblastoma, an aggressive childhood cancer
5. Researchers Find Gene Location That Gives Rise to Neuroblastoma, an Aggressive Childhood Cancer
6. Researchers Publish Genome Sequence for Duck-Billed Platypus
7. UC San Diego researchers target tumors with tiny nanoworms
8. Researchers Find Lubricant Doesnt Hinder Fertility
9. MGH researchers report successful new laser treatment for vocal-cord cancer
10. Stanford researchers synthesize compound to flush HIV out of hiding
11. World first: researchers develop completely automated anesthesia system
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... Pittsburgh, PA (PRWEB) October 20, 2014 ... new, minimally-invasive procedure that enables physicians to repair a ... , The MitraClip system, developed by ... regurgitation (MR), a progressive and life-threatening condition in which ... allowing blood to flow backward from the heart’s left ...
(Date:10/20/2014)... 20, 2014 ASCNYC (ascnyc.org) is ... helps New Yorkers living with HIV/AIDS and other ... housing, recovery and self-sufficiency. Each year, ASCNYC spotlights ... community through their tireless efforts. , Savills ... , has been selected as this year’s honoree ...
(Date:10/20/2014)... T.E.N., a technology and information security ... William H. Murray, renowned author and industry visionary, ... Award winner. Presented annually, the ISE® Luminary Leadership ... and industry practitioner for his or her distinguished ... security industry. , Formerly with IBM, Murray is ...
(Date:10/20/2014)... Zereana Jess-Huff, a 34-year-old mother, corporate executive and ovarian ... to think outside the bra. She doesn’t try to hide ... awareness about women’s other lady parts. , "We have won ... color pink and everybody knows what you’re talking about,” Jess-Huff ... has not been won when it comes to gynecologic cancers. ...
(Date:10/20/2014)... WA (PRWEB) October 20, 2014 My ... workflow management software application. The new module enables ... patients receive full life-cycle quality care. , This application ... others within their practice, attach a to-do item to ... fit, and even set up reoccurring reminders for follow-ups. ...
Breaking Medicine News(10 mins):Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 2Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 3Health News:Savills Studley's Marc Shapses To Be Honored as 2014 "Positive Changemaker" by ASCNYC 2Health News:Savills Studley's Marc Shapses To Be Honored as 2014 "Positive Changemaker" by ASCNYC 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 2Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 4Health News:Ovarian Cancer Survivor Mrs. Maryland Urges Media to Think Outside the Bra 2Health News:Ovarian Cancer Survivor Mrs. Maryland Urges Media to Think Outside the Bra 3Health News:My Clients Plus Announces New Workflow Management Software 2
... cases due to infectious diseases, researchers report , TUESDAY, ... pneumonia, diarrhea, malaria and blood poisoning account for more ... kids under 5 years of age worldwide, a new ... children include birth complications, lack of oxygen during birth ...
... ... President Obama to investigate BBC News reports that detainees being held by US forces ... being subjected to prolonged isolation, temperature manipulation, and sleep deprivation. , ... Cambridge, MA (Vocus) -- Physicians for ...
... could lead to future treatments, researchers say , TUESDAY, ... genes that are linked to Alzheimer,s disease and could ... , Genetic variants appear to play an important part ... siblings with the disease increases a person,s risk. It ...
... The University of Oklahoma Health Sciences Center announced today ... grant from the Bill & Melinda Gates Foundation. ... project conducted by Sunil K. Joshi, assistant professor in ... Safe, Cost-effective, and Functional Strategy for Immune Intervention." ...
... in neighbourhoods where they perceived traffic made it unpleasant to ... those who didn,t, according to a new University of Alberta ... socio-economic status (SES), and changes in body mass index (BMI) ... the surprise findings in the study, led by Tanya Berry, ...
... improve blood flow , TUESDAY, May 11 (HealthDay News) -- ... "The View" Monday when she announced she was preparing to ... her off the air until the fall. , But doctors ... considered a routine procedure that typically leads to a full ...
Cached Medicine News:Health News:Almost Half of Deaths in Kids Under 5 Occur in 5 Countries 2Health News:President Obama Must Investigate Reports of Detainee Abuse at Bagram Air Base 2Health News:New Alzheimer's Risk Genes Identified 2Health News:New Alzheimer's Risk Genes Identified 3Health News:OUHSC receives $100,000 Grand Challenges Explorations grant for innovative global health research 2Health News:Traffic density and increased BMI linked 2Health News:Barbara Walters' Prognosis Is Excellent, Doctors Say 2Health News:Barbara Walters' Prognosis Is Excellent, Doctors Say 3
(Date:10/22/2014)... 22, 2014 AVACEN Medical announced today that ... (k) OTC clearance by the U.S. Food and Drug ... marketed over the Internet for: the temporary relief ... minor strains and sprains . Logo - ... (MSRP $2495) is a sophisticated medical device incorporating over ...
(Date:10/22/2014)... 21, 2014   BioNano Genomics , the ... research centers to purchase an Irys™ System . ... Cancer Institute (NCI), NIH Intramural Sequencing Center (NISC) and ... obtaining a comprehensive view of a genome was ... does not deliver the scalability or reliability to ...
(Date:10/22/2014)... , Oct. 22, 2014 InVivo Therapeutics ... MA is revolutionizing spinal cord injury (SCI) ... been shown to outperform in tissue regrowth in the ... scaffold.  Made from an FDA approved polymer, the scaffold ... it harmless to the human body. NVIV has recently ...
Breaking Medicine Technology:AVACEN Medical Announces FDA Clearance of First Medical Device with Internal Game Mode 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 3InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 2InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: