Navigation Links
Researchers use sugar to halt esophageal cancer in its tracks
Date:1/15/2012

Scientists working at the Medical Research Council have identified changes in the patterns of sugar molecules that line pre-cancerous cells in the esophagus, a condition called Barrett's dysplasia, making it much easier to detect and remove these cells before they develop into esophageal cancer. These findings, reported in the journal Nature Medicine, have important implications for patients and may help to monitor their condition and prevent the development of cancer.

Oesophageal cancer is the fifth biggest cause of cancer death in the United Kingdom and the eighth leading cause of cancer deaths for men in the United States. Moreover, the number of people diagnosed with this disease is increasing rapidly. Individuals with a pre-cancerous condition known as Barrett's oesophagus are at an increased risk of developing esophageal cancer, and need to be closely monitored to make sure that the disease is not progressing.

Dysplasia offers a stage at which cancer can be prevented by removing these cells. However correctly identifying these areas has proved to be problematic, as they can easily be missed during endoscopy and biopsy, which only take samples from a small part of the esophagus. This can result in false reassurance for patients in whom their dysplasia has been missed, and conversely those without dysplasia having to undergo further unnecessary treatments.

The team, based at the MRC Cancer Cell Unit in Cambridge, was led by Dr. Rebecca Fitzgerald and included New York University's Lara Mahal, an associate professor of chemistry, and William Eng, a laboratory technician.

The researchers discovered a new mechanism for identifying Barrett's dysplasia cells by spraying on a fluorescent probe that sticks to sugars and lights up any abnormal areas during endoscopy. By analyzing the sugars present in human tissue samples taken from different stages on the pathway to cancerusing microarray technology developed by NYU's
'/>"/>

Contact: James Devitt
james.devitt@nyu.edu
212-998-6808
New York University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Little Known About How Autism Affects Teen Drivers: Researchers
2. Researchers find new, noninvasive way to identify lymph node metastasis
3. Hopkins researchers find Google Flu Trends a powerful early warning system for emergency departments
4. Researchers Look at Genomes of Nonsmokers With Lung Cancer
5. Researchers discover new culprit in atherosclerosis
6. TGen researchers map potential genetic origins, pathways of lung cancer in nonsmokers
7. Researchers Identify Liver Cancer Risk Factors
8. Researchers find malignancy-risk gene signature for early-stage non-small cell lung cancer
9. Potential Herpes Vaccine Disappoints Researchers
10. Fibroblasts contribute to melanoma tumor growth, say Moffitt Cancer Center researchers
11. Researchers discover protein that may represent new target for treating type 1 diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... gas prices rose in recent years, so did motorcyclist ... times of gas increases, more people start using motorcycles ... explained. They examined data gathered between 2002 and ... motorcycle registrations in the United States and the third ... a strong association between rising gas prices and an ...
(Date:12/17/2014)... News) -- Greater participation in music classes may benefit ... followed kids in the nonprofit Harmony Project, which provides ... Angeles. Over two years, children who actively participated ... brain processes speech and reading, compared to those with ... active participation in music classes occurred in the same ...
(Date:12/15/2014)... 2014 A recent survey found that ... as impacting skin health and beauty were: “Connections,” “climate,” ... care.” Water and health advocate and radio host Sharon ... describing the survey and the Four C’s.* Kleyne notes, ... category discussed would benefit from paying attention to one’s ...
(Date:12/15/2014)... Beach, FL (PRWEB) December 15, 2014 South ... , knows that holidays can be a daze of hassle, ... slips and falls while decking halls, to burns when making ... of holiday hazards that can happen at any time. To ... pain, MD Now has made a list of helpful and ...
(Date:12/15/2014)... Steven Reinberg HealthDay Reporter ... study should reassure the millions of American women who have ... cancer. "There is no association between migraine and breast ... of medicine at Harvard Medical School. "There is no positive ... is no protective effect either." About 18 percent of ...
Breaking Medicine News(10 mins):Health News:When Gas Prices Go Up, So Do Motorcycle Accidents, Study Finds 2Health News:Music Classes Boost Language Skills, Study Says 2Health News:Water and health advocate Sharon Kleyne adds a “W” for fresh water to “four C’s of skin care” 2Health News:Water and health advocate Sharon Kleyne adds a “W” for fresh water to “four C’s of skin care” 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News: No Link Between Migraine, Breast Cancer Risk, Study Says 2
... ... ... Professions, in partnership with the Nassau County (N.Y.) Department of Health, will hold a H1N1 ... for all members of the NYIT community and their families, as well residents of the ...
... ... received approval for re-accreditation by the American College of Radiology (ACR) , ... Berkeley Heights (Vocus) February 2, ... American College of Radiology (ACR) for the period of January 2010 through January 2013. ...
... ... List , ... Ariz. (Vocus) February 2, 2010 -- A Tucson retirement community’s health center, Sonora at ... and World Report. The designation will appear in the national magazine’s February 2010 issue. ...
... , , , , BEIJING ... ( SVA),("Sinovac" or the "Company"), a leading China -based ... offering was,closed on February 2, 2010 . Sinovac received ... discounts and commissions and,estimated offering expenses payable by the Company, ...
... , , A new free ... residents save money on their medications at most pharmacies within the state. ... The Saints are going to the Super Bowl and we ... for our fellow Louisiana residents and offer the free drug ...
... ... in Next Two Years, According to New Report , ... La Jolla, Calif. (Vocus) February 2, 2010 -- The biomedical industry ... of innovation, job growth and revenue that will help lead the state to economic recovery, ...
Cached Medicine News:Health News:Nuclear Medicine at Summit Medical Group Earns ACR Re-Accreditation 2Health News:U.S. News & World Report Ranks Sonora at Splendido Among Top in Nation 2Health News:Sinovac Announces Closing of Common Share Offering 2Health News:Sinovac Announces Closing of Common Share Offering 3Health News:Who Dat Got Dem Free Drug Cards? 2Health News:Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 2Health News:Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 3Health News:Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 4Health News:Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 5Health News:Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 6Health News:Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 7
(Date:12/17/2014)... , Dec. 17, 2014  Strategic Health Services, ... software solutions, today announced a strategic agreement with QualCare, ... New Jersey regional marketplace.  This agreement ... the health and wellness solutions QualCare brings to its ... the surrounding region. QualCare plans cover ...
(Date:12/17/2014)... -- , The new Dompé ... information concerning the biopharmaceutical Group,s national and international clinical research ... the recently launched institutional website that is receiving accolades from ... a new chapter in the fascinating story of Drug Discovery ... panoramic hub on the world of clinical research, ranging from ...
(Date:12/17/2014)... and RALEIGH, N.C. , Dec. ... LLC (CTMC), and Integrated Clinical Trial Services, LLC ... retention for clinical trials announce that they have ... Marketing Services (i-CTMS). i-CTMS will provide a broad ... pharmaceutical, biotechnology and medical device companies. ...
Breaking Medicine Technology:Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 2Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 3Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 3Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3
... HUDIKSVALL, Sweden, Oct. 6 Nonin Medical, Inc. ... formerly MedAir AB, has changed its name to ... better serve Nonin Medical,s European customers and distributors. ... Nonin,s European capnography products, Nonin Medical AB will ...
... THOUSAND OAKS, Calif., Oct. 5 Amgen (Nasdaq: ... important studies from the Company,s oncology portfolio will be ... (ESMO) Congress, Oct. 8-12, 2010, in Milan, Italy. ... innovative therapeutic approaches. Amgen is exploring numerous biologic pathways ...
Cached Medicine Technology:Nonin Medical, Inc. Announces Capnography Division Name Change; Expands Swedish Manufacturing Facility to Become Full-Franchise European Sales, Distribution and Service Center 2Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 2Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 3Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 4Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 5Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 6Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 7Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 8Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 9Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 10Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 11Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 12Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 13Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 14Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 15Amgen Highlights Key Clinical Data to be Presented at European Society for Medical Oncology Congress 16
...
...
Ascent Primary Knee System with cruciate retaining, posterior stabilized and constrained components...
Ascent Primary Knee System with cruciate retaining, posterior stabilized and constrained components...
Medicine Products: