Navigation Links
Researchers use sugar to halt esophageal cancer in its tracks
Date:1/15/2012

Scientists working at the Medical Research Council have identified changes in the patterns of sugar molecules that line pre-cancerous cells in the esophagus, a condition called Barrett's dysplasia, making it much easier to detect and remove these cells before they develop into esophageal cancer. These findings, reported in the journal Nature Medicine, have important implications for patients and may help to monitor their condition and prevent the development of cancer.

Oesophageal cancer is the fifth biggest cause of cancer death in the United Kingdom and the eighth leading cause of cancer deaths for men in the United States. Moreover, the number of people diagnosed with this disease is increasing rapidly. Individuals with a pre-cancerous condition known as Barrett's oesophagus are at an increased risk of developing esophageal cancer, and need to be closely monitored to make sure that the disease is not progressing.

Dysplasia offers a stage at which cancer can be prevented by removing these cells. However correctly identifying these areas has proved to be problematic, as they can easily be missed during endoscopy and biopsy, which only take samples from a small part of the esophagus. This can result in false reassurance for patients in whom their dysplasia has been missed, and conversely those without dysplasia having to undergo further unnecessary treatments.

The team, based at the MRC Cancer Cell Unit in Cambridge, was led by Dr. Rebecca Fitzgerald and included New York University's Lara Mahal, an associate professor of chemistry, and William Eng, a laboratory technician.

The researchers discovered a new mechanism for identifying Barrett's dysplasia cells by spraying on a fluorescent probe that sticks to sugars and lights up any abnormal areas during endoscopy. By analyzing the sugars present in human tissue samples taken from different stages on the pathway to cancerusing microarray technology developed by NYU's
'/>"/>

Contact: James Devitt
james.devitt@nyu.edu
212-998-6808
New York University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Little Known About How Autism Affects Teen Drivers: Researchers
2. Researchers find new, noninvasive way to identify lymph node metastasis
3. Hopkins researchers find Google Flu Trends a powerful early warning system for emergency departments
4. Researchers Look at Genomes of Nonsmokers With Lung Cancer
5. Researchers discover new culprit in atherosclerosis
6. TGen researchers map potential genetic origins, pathways of lung cancer in nonsmokers
7. Researchers Identify Liver Cancer Risk Factors
8. Researchers find malignancy-risk gene signature for early-stage non-small cell lung cancer
9. Potential Herpes Vaccine Disappoints Researchers
10. Fibroblasts contribute to melanoma tumor growth, say Moffitt Cancer Center researchers
11. Researchers discover protein that may represent new target for treating type 1 diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/2/2014)... HealthDay Reporter WEDNESDAY, Oct. 1, ... the stops to rescue surgical patients in crisis are ... such heroism is questionable, a new study suggests. ... saving elderly patients with life-threatening complications after major surgery, ... senior author Dr. Amir Ghaferi. He is assistant professor ...
(Date:10/1/2014)... has shown that more than 80 per cent of ... The study found that medicines called ,JAK inhibitors, halted ... that is present in more than 80 per cent ... or are in clinical trials, for diseases including rheumatoid ... cancer is the second-most common cancer in Australia with ...
(Date:10/1/2014)... BOSTON (October 1, 2014) Despite a policy ... with developmental disabilities, this vulnerable population continues to ... of The Journal of the American Dental ... Medicine and Tufts University School of Dental Medicine ... factors influencing at-home oral care provided by caregivers ...
(Date:10/1/2014)... Hills, CA (PRWEB) October 01, 2014 ... internationally-franchised Fit Body Boot Camp fitness boot camps, he’s ... selling personal training , with sold out business summits, ... stint as marketing consultant to a recent Spike TV ... Keuilian says that now is the time for personal ...
(Date:10/1/2014)... October 01, 2014 Farmington Company ... a redefined mission and visual identity helping brokers, ... partnering with them to create greater benefit communication ... that focuses on empowering customers to better leverage ... The crown jewel of the rebrand is the ...
Breaking Medicine News(10 mins):Health News:'High-Intensity' Hospitals Save More Elderly After Surgery: Study 2Health News:'High-Intensity' Hospitals Save More Elderly After Surgery: Study 3Health News:Eighty percent of bowel cancers halted with existing medicines 2Health News:To improve oral health of adults with developmental disabilities, support caregivers 2Health News:To improve oral health of adults with developmental disabilities, support caregivers 3Health News:Bedros Keuilian Shares Tips on Selling Personal Training for the Holidays 2Health News:Bedros Keuilian Shares Tips on Selling Personal Training for the Holidays 3Health News:Farmington Company Launches Rebrand and New Positioning 2
... Feb. 15 that a 70 % minimum requirement in the ... for admission to medical// and dental colleges in the open ... % of the weightage for admission in medical and dental ... common entrance test (CET), the government said it would be ...
... and sound health info Kerala and Goa have lifted the ... revealed by Minister for Medical Education and Animal Husbandry V.S. ... that this indicates that the situation is under control. ... make policies Chief Minister H.D. Kumaraswamy said the Government has ...
... charge contraceptives have a VAT of 17.5% on them. This ... in the ensuing budget.,Gordon Brown is due to present the ... Street chemist Superdrug which said that it was confident of ... said the move followed a successful 10-month campaign. ...
... Researchers from Texas A&M University said that poorly maintained ... breeding grounds for potentially lethal bacterial strains. They tested ... some kind of microbial growth.// ,Various Bacterial ... of the samples, while 81% had fungi and 34% ...
... Indian mind trainer and motivator has been helping South Africans ... subconscious mind. ,Jeetendra Adhia's workshops in various cities seek to ... the mind which he says lies between the conscious state ... never utilised more than 10 percent of their mind power," ...
... Researchers have developed a molecular map and other similar ... found in the Asian population//. ,'The inroads ... more effectively,' said Professor Soo Khee Chee, director of ... led by the NCC included experts from the University ...
Cached Medicine News:
(Date:9/30/2014)... This report analyzes the worldwide markets for Enteral Feeding Devices ... Pumps, Nasogastric Tubes, and Others. The report provides ... , Europe , Asia-Pacific ... of World. Annual estimates and forecasts are provided for the ... provided for these markets. The report profiles 38 ...
(Date:9/30/2014)... BEDFORD, Mass. , Sept. 30, 2014  Hologic, ... Stephen MacMillan , Hologic,s President and Chief Executive ... Bell Ceremony on October 1, the first day of ... will discuss the Company,s campaign focused on the important ... system approved by the FDA as clinically superior to ...
(Date:9/30/2014)... ROCKVILLE, Md. , Sept. 30, 2014 /PRNewswire/ ... natural way to modernize medicine, announced today the ... line of nutraceuticals developed to address men and ... staying healthy and vibrant into old age while ... line includes three condition-specific, whole-food and herb-based formulas, ...
Breaking Medicine Technology:Global Enteral Feeding Devices Industry 2Global Enteral Feeding Devices Industry 3Global Enteral Feeding Devices Industry 4Global Enteral Feeding Devices Industry 5Global Enteral Feeding Devices Industry 6Global Enteral Feeding Devices Industry 7Global Enteral Feeding Devices Industry 8Global Enteral Feeding Devices Industry 9Global Enteral Feeding Devices Industry 10Global Enteral Feeding Devices Industry 11Global Enteral Feeding Devices Industry 12Global Enteral Feeding Devices Industry 13Global Enteral Feeding Devices Industry 14Global Enteral Feeding Devices Industry 15Global Enteral Feeding Devices Industry 16Global Enteral Feeding Devices Industry 17Global Enteral Feeding Devices Industry 18Global Enteral Feeding Devices Industry 19Hologic to Kick Off National Breast Cancer Awareness Month at the October 1 NASDAQ Stock Market Opening Bell Ceremony 2Hologic to Kick Off National Breast Cancer Awareness Month at the October 1 NASDAQ Stock Market Opening Bell Ceremony 3
... Therapy Services Holdings, Inc. ("Radiation Therapy Services" or the "Company") ... Wells Fargo Securities 2011 Healthcare Conference on Wednesday, June 22, ... held at the Intercontinental Hotel in Boston, MA. ... available by visiting the Events section of the Company,s Web ...
... ERT ), announced today that Keith ... present at the 2011 Wells Fargo Securities Healthcare ... in Boston. Interested parties may access ... at  http://www.ert.com . The webcast may also be ...
Cached Medicine Technology:ERT to Present at the 2011 Wells Fargo Securities Healthcare Conference on June 23, 2011 2
Suture Cutters, Straight...
Suture scissor...
Threaded cannula for use with Suretac® II, sterile packs, box of 10....
The Small Oval Cannula System is designed to be the smallest oval cannula system currently available, and is utilized with the Caspari Suture Punch System. Disposable seals are available with this sy...
Medicine Products: