Researchers use cell 'profiling' to detect abnormalities -- includ... ( COLUMBUS Ohio -- An Ohio State Unive...)

Researchers use cell 'profiling' to detect abnormalities -- including cancer

Date:1/25/2011

COLUMBUS, Ohio -- An Ohio State University mathematician and his colleagues are finding ways to tell the difference between healthy cells and abnormal cells, such as cancer cells, based on the way the cells look and move.

They are creating mathematical equations that describe the shape and motion of single cells for laboratory analysis.

Though this research is in its early stages, it represents an entirely new way of identifying cell abnormalities, including cancer. It could one day be useful in gauging future stages of a disease -- for example, by detecting whether cancer cells are aggressive and likely to spread throughout the body, or metastasize.

In a paper published online in the Bulletin of Mathematical Biology, researchers describe a mathematical model which analyzes image sequences of single, live cells to determine abnormalities manifested in their shape and behavior. A brain tumor cell was one of the cell types they analyzed in the study.

Huseyin Coskun, visiting assistant professor of mathematics at Ohio State and leader of the project, described their novel approach as a first step toward developing mathematical tools for diagnosing cell abnormalities and for giving potential prognoses.

Because the technique would allow doctors to view how cancer cells behave under different physical or chemical conditions, it could also be used to test different treatment strategies for each individual patient -- such as determining the most efficient dose of chemotherapeutic agents or radiation -- or even to test entirely new treatments.

In addition, Coskun sees his technique as a tool for also pathologists, who typically look at photographs of biopsied cells to identify cancer and judge how advanced the cancer may be.

"A pathologist can diagnose cancer, but as far as predicting the future, they don't have many tools at their disposal -- particularly if a cancer is in its early stages," Cos
'/>"/>

Contact: Huseyin Coskun
coskun.5@osu.edu
614-292-5131
Ohio State University
Source:Eurekalert

0

GOOD

Page: 1 2 3
Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor

Post Your Comments:

(Date:6/17/2013)... New York (PRWEB) June 18, 2013 ... has more physicians listed in New York magazine's ... In the latest survey, 209 NewYork-Presbyterian physicians from ... fortunate to have some of the nation's best ... J. Corwin, CEO of NewYork-Presbyterian Hospital. "We are ...

(Date:6/17/2013)... and Drug Administration (FDA) imposes new graphic warning ... First Amendment challenge if they depict health consequences ... evidence, says a Georgetown University Medical Center public ... warning labelswhich combine images with health warningsare a ... other countries, but the tobacco industry argues they ...

(Date:6/17/2013)... MA (PRWEB) June 17, 2013 Daimer ... robust steam cleaner equipment , such as expertly designed ... launched the KleenJet® Pro Plus 200S for apartment dwellers ... up to 310°F in 15 minutes and pressure levels ... effectively. The machine can be used to clean carpet ...

(Date:6/17/2013)... Bust’DD (pronounced ‘busted’), a new company that ... women with large busts, will soon launch their crowdfunding campaign ... understand the problem of ill-fitting bras and want to offer ... is to raise at least $25,000 to create their beta ... on a wide scale. , In order to kick off ...

(Date:6/17/2013)... (PRWEB) June 17, 2013 Today, ... stand-alone HRAs for small businesses . Zane Benefits, ... employer sponsored health benefits, is the leader in ... arrangements . , According to Zane Benefits’ website, ... Accounts or HRAs, offer small businesses an affordable ...

Breaking Medicine News(10 mins):Health News:NewYork-Presbyterian Leads NY Metro Area Hospitals on New York Magazine's Annual ‘Best Doctors' List 2 Health News:Can new FDA graphic warning labels for tobacco pass a first amendment legal challenge? 2 Health News:Daimer Ships Vapor Steam Cleaner For Homeowners 2 Health News:Daimer Ships Vapor Steam Cleaner For Homeowners 3 Health News:Arizona Startup Bust’DD Looking to Start a BRAvolution 2 Health News:Arizona Startup Bust’DD Looking to Start a BRAvolution 3 Health News:Zane Benefits Publishes New Information on Stand-Alone HRAs for Small Businesses 2

[0] NewYork-Presbyterian Leads NY Metro Area Hospitals on New York Magazine's Annual ‘Best Doctors' List [0] Can new FDA graphic warning labels for tobacco pass a first amendment legal challenge?[0] Daimer Ships Vapor Steam Cleaner For Homeowners [0] Arizona Startup Bust’DD Looking to Start a BRAvolution [0] Zane Benefits Publishes New Information on Stand-Alone HRAs for Small Businesses

... , , , ... , the global leader in thin computing and client virtualization, today announced ... Smiles is a rapidly-growing company whose mission is to bring quality dental ... first office in 2002 in Atlanta, GA, the network has demonstrated substantial ...

... , , , ... Health, Inc. (Nasdaq: GHDX ) today announced that Kim ... Adams 29th Annual Global Growth Conference in Boston, on Thursday, August ... access the live and subsequently archived webcast of the presentation, visit ...

... , , , ... Aug. 6 CSC (NYSE: CSC ... company as a preferred provider to help member hospitals comply with the ... U.S. federal government stimulus package. Under the ARRA, hospitals will receive incentive ...

... TAMPA, Fla., Aug. 6 Gold Standard/Elsevier ... of three MedCounselor consumer drug information modules for pharmacies and ... to take medications safely, assists in identifying unknown tablets or ... indispensable in helping to increase consumer compliance to their drug ...

... , KIBBUTZ SHAMIR, Israel, Aug. 6 Shamir ... to issue its second quarter of 2009 earnings results on Thursday, August ... at 11:00 A.M. EDT that morning. , , ... listen live, please go to www.kcsa.com approximately five ...

... Va., Aug. 6 Sunrise Senior Living, Inc. (NYSE: ... second quarter of 2009. Sunrise will host a conference call ... discuss the financial results. , , "Our restructuring ... expense controls. In recent weeks we have seen a modest lift ...

Kool Smiles Relies on Wyse Technology Virtual Clients to Improve Patient Care and Security of Electronic Health Records (EHRs)Genomic Health to Present at Canaccord Adams 29th Annual Global Growth Conference CSC to Help Georgia Hospital Association Members Achieve 'Meaningful Use' of Electronic Health Records Gold Standard/Elsevier Launches MedCounselor Consumer Drug Information Modules Shamir Optical Industry Ltd. to Host Conference Call Announcing Second Quarter of 2009 Earnings Results Sunrise Reports Financial Results for Second-Quarter 2009

(Date:6/17/2013)... June 17, 2013 The American Society of ... report on the effectiveness of medications for opioid ... FDA-approved drugs by many state governments and insurance ... drunk driving car crashes, an epidemic led by ... heroin. Yet, safe and effective medications to treat ...

(Date:6/17/2013)... As the Share Repurchase Resolution has been passed at ... Corporation, plc (NYSE: ELN ) has lapsed in ... Proceedings referred to below and any consequent decision of the ... to the extent that it would have been had it ... Repurchase Resolution being passed. There can be no assurance as ...

(Date:6/17/2013)... 17, 2013 Southern Research Institute today ... been selected by its Board of Directors to serve ... 8, 2013. (Photo: http://photos.prnewswire.com/prnh/20130617/DC33167 ... III, Ph.D., who served as president and CEO of ... retirement earlier this year after 34 years of service ...

[0] Effective Rx thwarted for deadly opiate epidemic [0] Royalty Pharma Informs Elan Stockholders About The Consequences Arising From The Results Of The Elan EGM Earlier Today [0] Southern Research Institute Names Arthur J. Tipton, Ph.D. President and CEO

... CITY, Calif., March 1, 2011 OncoMed Pharmaceuticals, Inc., ... cells, today announced the publication of preclinical data demonstrating ... reduces cancer stem cell frequency when administered alone or ... with or without KRAS mutations. This study was published ...

... March 1, 2011 Wako Diagnostics, a division of ... U.S. Food and Drug Administration (FDA) to market the ... prothrombin (DCP) in vitro diagnostic (IVD) tests ... intended for use by healthcare professionals as an aid ...

Cached Medicine Technology:OncoMed Anti-Cancer Stem Cell Antibody OMP-21M18 Demonstrates Potent Activity in Preclinical Studies Against Human Colon Cancer Tumors Regardless of KRAS Mutation Status 2 OncoMed Anti-Cancer Stem Cell Antibody OMP-21M18 Demonstrates Potent Activity in Preclinical Studies Against Human Colon Cancer Tumors Regardless of KRAS Mutation Status 3 OncoMed Anti-Cancer Stem Cell Antibody OMP-21M18 Demonstrates Potent Activity in Preclinical Studies Against Human Colon Cancer Tumors Regardless of KRAS Mutation Status 4 OncoMed Anti-Cancer Stem Cell Antibody OMP-21M18 Demonstrates Potent Activity in Preclinical Studies Against Human Colon Cancer Tumors Regardless of KRAS Mutation Status 5 Announcing 510(k) Clearance of a New Microfluidic-based IVD Test System, the uTASWako® i30 Immunoanalyzer, and AFP-L3 and DCP Assays for Liver Cancer Risk Assessment. 2

OncoMed Anti-Cancer Stem Cell Antibody OMP-21M18 Demonstrates Potent Activity in Preclinical Studies Against Human Colon Cancer Tumors Regardless of KRAS Mutation Status Announcing 510(k) Clearance of a New Microfluidic-based IVD Test System, the uTASWako® i30 Immunoanalyzer, and AFP-L3 and DCP Assays for Liver Cancer Risk Assessment.

... to order tips. Each box contains 10,000 ... available in easy-to-open, re-sealable Bulk Packs of ... sealed with a tamper-proof strip which can ... Gilsons Diamond Tips. Bulk Packs are closed ...

200 L, Bulk, yellow Recommended for 20, 25, 50, 100 and 200 L pipettes. Can also be used with 300 L pipettes when pipetting 200 L or less....

... the Finntip Wide is designed especially for ... genomic DNA. This tip eliminates the mechanical ... excellent for use with extremely viscous liquids. ... of the orifice is 1.1 mm or ...

Capillary section fits into a 0.3-mm well for accurate loading of sequencing gels...

Medicine Products:

EcoPack D200 200 L Pipette Tip Finntip 250 Wide StrataTips Pipet Tips, Flat (1-200 l)