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Researchers use CT to predict heart disease
Date:9/27/2010

OAK BROOK, Ill. Using incidental findings from routine diagnostic CT, radiologists may be better able to identify people at high risk for cardiovascular disease, according to a new study appearing online and in the November issue of Radiology.

"The results of this study show that radiologists can predict cardiovascular disease fairly well using incidental findings of calcifications of the aortic wall on CT, along with minimal patient information, such as age, gender and the reason for the CT," said the study's lead author, Martijn J. A. Gondrie, M.D., from the Julius Center for Health Sciences and Primary Care at the University Medical Center Utrecht in the Netherlands. "Ultimately, this easily executed extra risk stratification has the potential to reduce future heart attacks or other cardiovascular events."

Over the past 10 years, the use of chest CT has increased substantially, and CT image quality has dramatically improved. As a result, many more incidental findings occur. Incidental findings are unexpectedly detected imaging characteristics that are unrelated to the original clinical indication for the CT.

Dr. Gondrie's study is part of the Prognostic Value of Ancillary Information in Diagnostic Imaging (PROVIDI) project, which aims to investigate the relevance of unexpectedly detected imaging findings on chest CT.

"This is the first study to investigate whether incidental findings can predict future disease in a routine care setting," Dr. Gondrie said. "Incidental findings are obtained without additional radiation exposure or cost to the patient and may hold valuable clues as to the patient's overall health and their risk for future disease."

Dr. Gondrie and colleagues developed prediction models incorporating incidental aortic findings detected on chest CT. From a total of 6,975 patients who had undergone diagnostic, contrast-enhanced chest CT for non-cardiovascular indications, a representative samp
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Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

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