Navigation Links
Researchers train the immune system to deliver virus that destroys cancer in lab models
Date:12/18/2007

s back into the mouse. Researchers found that once the T-cells returned to the lymph nodes and spleen, the virus detached itself from the T-cells, found the tumor cells, selectively replicated within them and extracted tumor cells from those areas.

CANCER VACCINE

The procedure used in this study triggered an immune response to cancer cells, which means that it could be used as a cancer vaccine to prevent recurrence.

We show that if you kill tumor cells directly in the tumor itself, you can get a weak immunity against the tumor, but if you use this virus to kill tumor cells in the lymph nodes, you get a higher immunity against the tumor, Dr. Vile says.

RESULTS

The technique used in this study successfully treated the cells of three different diseases: melanoma, lung cancer and colorectal cancer. The results include:

  • Two days after treatment, the presence of melanoma tumor cells in lymph nodes was significantly less, but not completely gone. There were no cancer cells in the spleen.

  • Ten-to-14 days after a T-cell transfer, both the lymph nodes and spleen were free of melanoma tumor cells.

  • Mice treated with a single dose of the T-cells transfer developed a potent T-cell response against melanoma tumor cells.

  • Although the procedure was not intended to treat the primary melanoma tumor, significant reductions in tumor cells were observed.

  • In mice with lung cancer metastasis, cancer cells were significantly reduced in one-third of mice and completely eradicated in two-thirds of mice. Efforts to clear metastases from colorectal tumors were similarly effective.

  • Lung and colorectal tumor cells were purged from lymph nodes. Also, the spleens of mice that had lung cancer developed immunity to the cancer after the treatment.

The technology already exists to extract T-cells from patie
'/>"/>

Contact: Amy Reyes
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2015)... As a result of the American ... Clearstream, LLC ’s products, services and company philosophies, ... products—led by their mPulse Hand Sanitizer—fits the core ... The AAPA—which represents a profession comprising than 100,000 ... specialties in the U.S.—advocates and educates on behalf ...
(Date:3/5/2015)... California (PRWEB) March 05, 2015 ... last week released a special issue ... the field of PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders ... Syndromes), an autoimmune reaction triggered by infections such ... which result in inflammation of the child's brain. ...
(Date:3/5/2015)... March 05, 2015 Wimbledon Health ... provides vascular, echocardiogram and NCV testing, announced ... the Chief Medical Officer. Dr. Artel will be responsible ... of the WimbledonMED program and the continued growth and ... about working with Wimbledon Health Partners as a consulting ...
(Date:3/5/2015)... March 5, 2015 – As National Patient Safety Awareness ... children’s hospitals around the country are affirming the critical ... safe as possible for their children. , A national ... Safety (SPS) and the Children’s Hospital Association—are collaborating to ... the hospital with their child. , “SPS is ...
(Date:3/5/2015)... The MTC 5-day Fundamental Implantology Course has ... a variety of dental disciplines, to offer implant placement ... the onset we wanted this course to be a ... the excellence of the lecturers and the sheer energy ... than satisfied our aims." , Unlike large-scale training ...
Breaking Medicine News(10 mins):Health News:Clearstream’s Line of MediDefense Antimicrobial Products Scores Affinity Partnership With American Academy of Physician Assistants (AAPA) 2Health News:Clearstream’s Line of MediDefense Antimicrobial Products Scores Affinity Partnership With American Academy of Physician Assistants (AAPA) 3Health News:Clearstream’s Line of MediDefense Antimicrobial Products Scores Affinity Partnership With American Academy of Physician Assistants (AAPA) 4Health News:Controversial Childhood Illness PANDAS the Focus of a Special Medical Journal Issue 2Health News:Controversial Childhood Illness PANDAS the Focus of a Special Medical Journal Issue 3Health News:Wimbledon Health Partners Appoints Chief Medical Officer to Attain Medicare Market Share 2Health News:Wimbledon Health Partners Appoints Chief Medical Officer to Attain Medicare Market Share 3Health News:Children’s Hospitals Offer Safety Tips for Patient Families During National Patient Safety Awareness Week 2Health News:Children’s Hospitals Offer Safety Tips for Patient Families During National Patient Safety Awareness Week 3Health News:Children’s Hospitals Offer Safety Tips for Patient Families During National Patient Safety Awareness Week 4Health News:MIS Global Training Center (MTC) Launches its Fundamental Implantology Course for Doctors - with a Difference 2
... Creates ... ... (Vocus) April 14, 2010 -- PMSI , one of the nation’s largest providers ... the nation’s leader in pain medication monitoring solutions, today announced a strategic partnership to ...
... in Alaska have discovered that lingering oil from the 1989 ... more than 20 years after the disaster. The research, published ... reveal long-term exposure to oil in harlequin ducks and demonstrates ... than years. The Exxon Valdez tanker ran aground on ...
... ... by HealthGrades, April 8, at the 2010 DTC National Conference. , ... Florham Park, N.J. (PRWEB) April 14, ... company for direct-to-consumer (DTC) marketing, today announced the winners of the 10th annual ...
... therapy, study found , WEDNESDAY, April 14 (HealthDay News) ... for developing blood clots, especially if they,re undergoing hormone ... it is important to consider thromboembolic [blood-clotting] side effects ... require endocrine treatment," said Mieke van Hemelrijck, lead author ...
... ... , ... 14, 2010 -- Tahitian Noni International (TNI) announced that just one month after ... have increased dramatically. Sales in North America have skyrocketed, and double digit growth was common ...
... ... Living Green and “Tip of the Day” at www.greenearthcleaning.com , featuring 365 easy ways ... ... environmentally friendly dry cleaning, GreenEarth Cleaning, LLC announced today the launch of a new feature ...
Cached Medicine News:Health News:PMSI and Ameritox Launch Program to Enhance Quality and Effectiveness of Opioid Therapy 2Health News:PMSI and Ameritox Launch Program to Enhance Quality and Effectiveness of Opioid Therapy 3Health News:Wildlife still exposed to Exxon Valdez oil 20 years after disaster 2Health News:2010 DTC National Advertising Award Winners Honored 2Health News:2010 DTC National Advertising Award Winners Honored 3Health News:Prostate Cancer Patients at Higher Risk of Blood Clots 2Health News:Prostate Cancer Patients at Higher Risk of Blood Clots 3Health News:Worldwide Sales in March Increase Dramatically At Tahitian Noni International 2Health News:GreenEarth Makes Every Day Earth Day with New Online Tools to Live a Greener Life 2Health News:GreenEarth Makes Every Day Earth Day with New Online Tools to Live a Greener Life 3
(Date:3/5/2015)... March 5, 2015 - Cross ... ( http://www.epa.eu ) - Hitachi Medical ... nuova generazione di OASIS* all,ECR 2015. Si tratta di ... campo da 1.2 T che migliora la capacità diagnostica ... nell,attenzione al comfort del paziente. Le nuove funzionalità di ...
(Date:3/5/2015)... Mar. 05, 2015 Research and Markets ... "Japan Pharma Outlook 2015: Year to Watch out ... report to their offering. The ... from April -2014 (Annexure 1) is a game ... whether generic or innovator. The most of the companies ...
(Date:3/5/2015)... N.J. , March 5, 2015  ContraVir Pharmaceuticals, ... focused on the development and commercialization of targeted antiviral ... 27 th Annual ROTH Conference, to be held ... James Sapirstein , Chief ... business during his live presentation and will be available ...
Breaking Medicine Technology:Hitachi Medical Systems Europe lancia la nuova generazione di OASIS*: Il sistema di RM aperta ad alto campo da 1.2 T. Ancora più valore al paziente 2Hitachi Medical Systems Europe lancia la nuova generazione di OASIS*: Il sistema di RM aperta ad alto campo da 1.2 T. Ancora più valore al paziente 3Hitachi Medical Systems Europe lancia la nuova generazione di OASIS*: Il sistema di RM aperta ad alto campo da 1.2 T. Ancora più valore al paziente 4Japan Pharma Outlook 2015: Year to Watch out for Authorized Generics (AGs), Biosimilars and Overseas Strategic Initiatives 2Japan Pharma Outlook 2015: Year to Watch out for Authorized Generics (AGs), Biosimilars and Overseas Strategic Initiatives 3ContraVir to Present at 27th Annual ROTH Conference 2
... ,, NEW YORK , July 6 Reportlinker.com announces that a ... , , ... Growth Opportunities , , , ... , , , ...
... (Nasdaq: BIOD ) announced today that the following oral and poster presentations describing results ... and Exposition of the Controlled Release Society in Portland, Oregon , U.S.A. next week. ... Oral Presentation : , ... Oral session on peptides and proteins, Monday July 12, 2010 4:00 PM ...
Cached Medicine Technology:Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 2Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 3Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 4Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 5Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 6Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 7Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 8Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 9Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 10Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 11Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 12Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 13Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 14Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 15Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 16Reportlinker Adds Surgical Equipment Market to 2016 - Emerging Economies to Provide Future Growth Opportunities 17Biodel Announces Schedule for Presentations at the 37th Annual Meeting and Exposition of the Controlled Release Society 2
... Loading Units With Titanium Staples ... TA™ (Single Use Reloadable Stapler ... Auto Suture™ PREMIUM MULTIFIRE TA™ ... gynecological, pediatric and thoracic surgical ...
... Single Use Loading Units ... Series™ (Single Use Reloadable Staplers ... Auto Suture™ TA™ Reloadable staplers ... pediatric and thoracic surgical procedures ...
... Single Use reloadable linear stapler for resection, ... ,The Auto Suture™ MULTIFIRE GIA™ 60 and ... GIA™ 60 and 80 single use loading ... 60 knifeless single use surgical stapler with ...
... with titanium staples and in-line handle., ... use in the resection or transection of ... a double staggered row (or triple staggered ... of titanium staples and is available in ...
Medicine Products: