Navigation Links
Researchers to develop next generation immunotherapy for children with deadly solid tumors
Date:4/3/2013

Recently, research using adoptive T-cell immunotherapy in blood cancers have shown success, most notably in the case of a seven-year-old girl whose leukemia went into remission using altered T-cells and a disabled HIV virus. Now, two of the pediatric cancer scientists involved in the T-cell/HIV study will develop a new experimental cancer immunotherapy treatment option for children with high-risk solid tumors based on the same novel approach that uses a patient's own T-cells to attack tumor cells.

Researchers at the Children's Hospital of Philadelphia, the University of Pennsylvania, and the Primary Children's Medical Center of Salt Lake City received a $550,000 collaborative grant to test next generation T-cell immunotherapy strategies in children with neuroblastoma, a solid tumor with poor prognosis that is responsible for 15% of all childhood cancer deaths. The awardees were selected within a rigorous peer-review process through a new initiative called ACT FAST (Adoptive Cell Therapy For Adolescent/pediatric Solid Tumor), which is spearheaded by Solving Kids' Cancer. ACT FAST aims to fast-track promising research into a clinical trial within one year of the award through a collaborative team of researchers.

"Only a handful of cancer centers in the world have the capabilities and the infrastructure to implement adoptive cell therapy," said Scott Kennedy, the Executive Director of Solving Kids' Cancer. "Our goal in bringing together these researchers and institutions was to harness their collective power in bringing faster cures to kids with neuroblastoma."

The National Cancer Institute (NCI) and the Society for the Immunotherapy of Cancer (SITC) provided strategic counsel and expert review of the grant award, which was jointly funded by Solving Kids' Cancer, the Pierce Phillips Charity, and the Catherine Elizabeth Blair Memorial Foundation.

The clinical trial will be the first to use transiently modified T-cells in childr
'/>"/>

Contact: Jenny Song
jenny@solvingkidscancer.org
212-588-6625
Solving Kids' Cancer
Source:Eurekalert

Page: 1 2

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Researchers develop a new cell and animal model of inflammatory breast cancer
3. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
4. Researchers Find Gene Mutations That May Be a Key to Autism
5. Researchers find evidence of banned antibiotics in poultry products
6. NJ stroke researchers report advances in spatial neglect research at AAN Conference
7. Autism by the numbers: Yale researchers examine impact of new diagnostic criteria
8. Researchers Map Brain Regions Linked to Intelligence
9. Researchers ID Genes That May Determine Mental Illness
10. Researchers Develop Blood Test for Depression
11. University of Cincinnati researchers win $3.7M grant from US Department of Defense
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... (PRWEB) December 26, 2014 Cooking ... of 3.1 out of 5. This score reflects slightly ... level of product specialization, low switching costs and a ... reduced by the low availability of substitutes for cooking ... price of steel and aluminum, key inputs in the ...
(Date:12/26/2014)... December 26, 2014 “Many people become ... personal injury claim issues and phone calls with insurance ... an article featuring their free eBook on pedestrian ... eBook on pedestrian and bicycle auto accident claims assures ... fully capable of professionally handling their case while they ...
(Date:12/26/2014)... (PRWEB) December 26, 2014 Parker ... for the best in heating, cooling and plumbing ... 24 hour emergency services in 2014 with regard ... know that Arizona is known for its incredibly ... that understands the intricacies and details of a ...
(Date:12/25/2014)... The report “Nintedanib (Colorectal Cancer) ... on the current treatment landscape, unmet needs, current ... market. Stivarga is a drug which is used ... Boehringer Ingelheim is developing nintedanib (BIBF-1120), an orally ... CRC in the US, Europe, and Japan. The ...
(Date:12/25/2014)... 26, 2014 Recently, iFitDress.com, the popular online ... has announced its new selection of black one-shoulder cocktail ... sale now; they are available at discounted prices, up to ... promotion will last for three weeks only. You know, we ... who are interested in our new items can visit our ...
Breaking Medicine News(10 mins):Health News:Cooking & Warming Equipment Procurement Category Market Research Report from IBISWorld has Been Updated 2Health News:Cooking & Warming Equipment Procurement Category Market Research Report from IBISWorld has Been Updated 3Health News:Guide to Handling Pedestrian and Bicycle Accidents Released By The Jones Firm, Featured in Recent Article 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2
... report published in the January/February issue of General Dentistry, ... says that most children's medicines have the potential to ... in them. // ,For example, antihistamine syrups contain ... pH levels, which mean that they are high in ...
... alcohol dependence is greatly increased if an individual has a ... on the tongue // . The taste receptor gene, called ... at the Washington University School of Medicine have studied more ... of the family participated in a study called Collaborative Study ...
... very little precautionary measures can be taken to actually prevent ... infection in humans is actually caused by the H5N1 strain ... global pandemic it has issued various guidelines which will reduce ... The government says that as such there is no vaccine ...
... Australian Health Minister Tony Abbott told the press that all the ... they consulted qualified health care // personnels. ,This ... rural areas. But in a period of six months this plan ... ,This plan will help in reducing the amount of expenditure ...
... Museum in London has found a unique way to help people ... the much-needed dose of light // . ,The Dana ... dark winter days. ,Up to 500,000 people, a majority ... affective disorder. SAD is more common in the northern latitudes ...
... The worldwide scare of bird flu pandemic as increased which ... bird flu drug by many countries//. U.S. has stocked more ... producing the generic version of the drug Tamiflu manufactured by ... rush for shikimic acid which is used for production of ...
Cached Medicine News:Health News:Genetic Variation In Bitter-Taste Receptor Gene Increases Alcoholic Risk 2
(Date:12/24/2014)... , Dec. 24, 2014 Kinex Pharmaceuticals ... with KX2-361 at Roswell Park Cancer Institute. ... molecule drug that has shown potent inhibitory activity against ... those that are resistant to Temozolomide (T98G), the most ... In a well-established brain tumor mouse model, KX2-361 consistently ...
(Date:12/24/2014)... FLINT, Mich. , Dec. 24, 2014  Diplomat ... largest independent specialty pharmacy, is proud to announce ... and quality at Diplomat, will take office as the ... 2015. The formal induction ceremony will take place Feb. ... which will be held at the Renaissance Center in ...
(Date:12/24/2014)... , Dec. 23, 2014 Echo Therapeutics, ... device company focused on skin permeation, continuous glucose ... Scott W. Hollander has been appointed Chief ... has more than 20 years of experience in ... and most recently served as Vice President, Business ...
Breaking Medicine Technology:Kinex Pharmaceuticals Announces First Patient Dosed with KX2-361 in a Phase 1 Clinical Study 2Kinex Pharmaceuticals Announces First Patient Dosed with KX2-361 in a Phase 1 Clinical Study 3Diplomat's senior director of education and quality to be inducted as 2015 president of the Michigan Pharmacists Association 2Diplomat's senior director of education and quality to be inducted as 2015 president of the Michigan Pharmacists Association 3Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 2Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 3
... Colo., Dec. 21, 2010 Mesa Laboratories, Inc. (Nasdaq: ... of electronic instruments and disposables today announced the acquisition ... a North Carolina based company.  The acquisition of the ... Mesa,s earnings per share. Apex Labs is ...
... 21, 2010 Pepex Biomedical, Inc. has unveiled ... dependent diabetics which will combine regular glucose monitoring ... company is developing a complete product line of ... glucose levels and insulin delivery, appropriate to each ...
Cached Medicine Technology:Mesa Labs Acquires the Biological Indicators Business of Apex Laboratories, Inc. 2Pepex™ Unveils Development of First All-In-One Blood Glucose Meter 2
... in small and large sizes, noise is ... silver/silver chloride disposable tabs. For use with ... (contact surface): large tabs-2.2 x 2.5 cm ... (0.5 in) square. Each 100-count package contains ...
Four disposable disc electrodes are pre-gelled and attached to wires in red, blue, black and green. 4mil carbon film, Ag/AgCl coated. Each package contains 20 individually sealed sets of four leads....
Representing the next step in the evolution of point-of-care testing, the i-STAT 1 Analyzer uses one platform to perform glucose strip testing along with all i-STAT test cartridges....
Lancet cut ultra sharp tip for low penetration resistance. Low noise and impedance level giving you a clear and reliable signal. Stainless steel needle, color coded attached lead wires. Needles sold ...
Medicine Products: