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Researchers to Present Additional Data on Soliris(R) (eculizumab) for the Treatment of PNH at the ASH Annual Meeting
Date:11/10/2008

Initial Physician Experience with Eculizumab in Patients with Other Rare Complement-Mediated Diseases also to be Presented

CHESHIRE, Conn., Nov. 10 /PRNewswire-FirstCall/ -- Alexion Pharmaceuticals, Inc. (Nasdaq: ALXN) today announced that the American Society of Hematology (ASH) has published additional data relating to Soliris(R) (eculizumab) as a treatment for patients with paroxysmal nocturnal hemoglobinuria (PNH). Data also have been published regarding initial experience with eculizumab in patients with two other rare diseases (Atypical Hemolytic Uremic Syndrome and Cold Agglutinin Disease). Abstracts will be presented at the 50th Annual Meeting of the American Society of Hematology, to be held December 6 to 9, 2008 at the Moscone Center in San Francisco.

The following abstracts will be presented as oral presentations on Monday, December 8, 2008. The abstracts and presentation information can be accessed through the links provided below.

-- "Eculizumab Therapy Results in Rapid and Sustained Decreases in

Markers of Thrombin Generation and Inflammation in Patients with

PNH," Dr. Ilene Weitz, et al.

Abstract: http://ash.confex.com/ash/2008/webprogram/Paper8206.html

-- "Eculizumab Reduces Pulmonary Hypertension Through Inhibition of

Hemolysis-Associated Nitric Oxide Consumption in Patients With

Paroxysmal Nocturnal Hemoglobinuria," Dr. Anita Hill, et al.

Abstract: http://ash.confex.com/ash/2008/webprogram/Paper9815.html

The following abstracts will be presented in post
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SOURCE Alexion Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
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