Navigation Links
Researchers suggest new paradigm for breast cancer screening
Date:6/29/2010

Washington, DC -- Should we spend more money urging women to use mammography screening on a regular basis or should those dollars and effort be used for discovering and developing better early detection tests?

In an editorial published online June 29 in issue 14 of the Journal of the National Cancer Institute (JNCI), Jeanne S. Mandelblatt, MD, MPH, of the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center in Washington, DC, and Diana S.M. Buist, PhD, MPH of Group Health Research Institute in Seattle, suggest the latter, pointing to the limitations of mammography and calling it an "imperfect technology."

Their editorial accompanies a review and meta-analysis by Sally W. Vernon, MD, and colleagues of the effectiveness of intervention strategies such as educational outreach, counseling and simple reminders to encourage women to get repeat mammograms. In their editorial, Mandelblatt and Buist call the results "sobering" because behavioral interventions appear to only increase repeat screening rates by a small or moderate amount with insufficient evidence to know which approaches are the most effective.

"These results are all the more discouraging since the reviewed studies focused on getting women to undergo only one to two repeat screening examinations, not the 12 to 13 presently recommended for average risk women biennially from age 50 to 74," they write.

The reasons why interventions fail could be because "women are making an informed choice not to use an imperfect technology" the authors write. They point to media attention highlighting the fact that mammograms miss many cancers while detecting lesions that are false positives or ones that are never destined to become cancer.

Noting studies that suggest women with an increased risk of developing breast cancer have greater adherence to routine screening, the authors say interventions might be more effective in such subgroups, though this was not examined by the meta-analysis.

Mandelblatt and Buist also support the use of modeling to help understand the various factors that impact screening. Specifically, they highlight the work of the NCI-funded Cancer Intervention and Surveillance Modeling Network (CISNET) as an excellent example of the application of modeling to determine the most profitable avenues for intervention. Mandelblatt and others from CISNET are collaborating with Buist and her colleagues from the Breast Cancer Surveillance Consortium on modeling research to examine how risk level affects choice of screening modality and optimal ages of use.

Still, the authors offer a strong recommendation in order to realize the promise of eliminating the burden of cancer. "It could be reasonably argued that we should better spend our efforts in discovering better early detection tests.

"New paradigms guided by evidence from modeling, novel trials and new scientific discovery will be needed."


'/>"/>

Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Source:Eurekalert

Related medicine news :

1. Of lice and man: Researchers sequence human body louse genome
2. AcademyHealth honors leading health services researchers
3. UCLA researchers, US military collaborate to open center for traumatic brain injury
4. UCSD researchers receive $2.5 million in new stem cell grants
5. Researchers find key to getting estrogens benefits without cancer risk
6. Mount Sinai researchers find structural basis for incidence of skin cancers in a genetic disorder
7. WSU researchers find mothers of children with autism pay price in workplace
8. Free Resources from EBSCO Publishing Providing Useful Information to Researchers
9. University of Utah researchers fight genetic killer of infants and toddlers
10. Researchers identify key enzyme in melanoma cell development
11. Researchers predict human visual attention using computer intelligence for the first time
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... ... 13, 2017 , ... Coveros, a leader in agile coaching ... contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile ... of Agile methodologies in a consistent and high value manner across CMS programs. ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... now treating sleep apnea using cutting-edge Oventus O2Vent technology. As many ... sleep disorder characterized by frequent cessation in breathing. Oral appliances can offer significant ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) will ... during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual ... F. Collen, a pioneer in the field of medical informatics, this prestigious award is ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader ... a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were ... 11, 2017. , The annual award competition recognizes editorial and design excellence across a ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... 2017 West Pharmaceutical Services, Inc. ... injectable drug administration, today announced that it will release ... Thursday, October 26, 2017, and will follow with a ... at 9:00 a.m. Eastern Time. To participate on the ... conference ID is 94093362. ...
(Date:10/10/2017)... Oct. 10, 2017  NDS received FDA 510(k) clearance in May ... battery-powered display stand specifically designed for endoscopy environments. An innovative secondary ... a clinical solution to support the improvement of patient outcomes, procedural ... ... ...
(Date:10/4/2017)... the Centers for Disease Control and Prevention (CDC), influenza vaccination should ... helping communities across Massachusetts , Connecticut ... shots through the end of the month. *Some exclusions apply ... ... is by the end of October, according to the Centers for Disease ...
Breaking Medicine Technology: