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Researchers suggest new paradigm for breast cancer screening
Date:6/29/2010

Washington, DC -- Should we spend more money urging women to use mammography screening on a regular basis or should those dollars and effort be used for discovering and developing better early detection tests?

In an editorial published online June 29 in issue 14 of the Journal of the National Cancer Institute (JNCI), Jeanne S. Mandelblatt, MD, MPH, of the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center in Washington, DC, and Diana S.M. Buist, PhD, MPH of Group Health Research Institute in Seattle, suggest the latter, pointing to the limitations of mammography and calling it an "imperfect technology."

Their editorial accompanies a review and meta-analysis by Sally W. Vernon, MD, and colleagues of the effectiveness of intervention strategies such as educational outreach, counseling and simple reminders to encourage women to get repeat mammograms. In their editorial, Mandelblatt and Buist call the results "sobering" because behavioral interventions appear to only increase repeat screening rates by a small or moderate amount with insufficient evidence to know which approaches are the most effective.

"These results are all the more discouraging since the reviewed studies focused on getting women to undergo only one to two repeat screening examinations, not the 12 to 13 presently recommended for average risk women biennially from age 50 to 74," they write.

The reasons why interventions fail could be because "women are making an informed choice not to use an imperfect technology" the authors write. They point to media attention highlighting the fact that mammograms miss many cancers while detecting lesions that are false positives or ones that are never destined to become cancer.

Noting studies that suggest women with an increased risk of developing breast cancer have greater adherence to routine screening, the authors say interventions might be more effective in such subgroups, tho
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Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Source:Eurekalert

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