Navigation Links
Researchers study vaccine as potential weapon against aggressive brain tumors
Date:7/24/2012

CHICAGO Researchers at Northwestern Brain Tumor Institute (NBTI) are seeking to understand if a vaccine made from a patient's own blood cells may slow the growth of a type of brain tumor. The trial is studying the vaccine's effect on glioblastoma multiformes (GBM), the most common and aggressive type of primary brain tumor. The trial is an example of a growing trend in cancer research that seeks to understand if vaccines can be used to turn a person's own immune system into a weapon against cancers by slowing the growth of tumors.

GBMs, which occur in up to 10,000 Americans annually, are typically treated with surgical resection of the tumor followed by chemotherapy and radiation treatment. "Glioblastomas are complicated to treat because they are aggressive, fast-growing tumors that are often resistant to standard treatment," said principal investigator James Chandler, MD, co-director of the NBTI and surgical director of neuro-oncology at Northwestern Memorial Hospital. "In this trial, a vaccine is made using the person's own white blood cells, which we hope will have the power to stimulate an immune response to kill brain tumor cells."

The vaccine, called ICT-107, is created by collecting the participant's white blood cells through a process called apheresis, which separates the components in the blood. The white blood cells are then treated to recognize the tumor cells turning them into immune cells, which early research indicates may be able to recognize and attack the tumor cells. Patients receive the vaccine in addition to standard treatment.

"Vaccines hold great promise as potential treatments for all types of cancer," said Chandler, who is also a professor of neurological surgery at Northwestern University Feinberg School of Medicine. "More researchers are looking at this as a way to prompt an immune response to slow tumor growth and fight the cancer."

The phase II trial will examine both safety and efficacy of th
'/>"/>

Contact: Megan McCann
memccann@nmh.org
312-926-5900
Northwestern Memorial Hospital
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers developing bioadhesive gel to protect women from HIV and HSV infections
2. Researchers find driver of breast cancer stem cell metastasis
3. Researchers unfold the mechanisms underlying blood disorders
4. New lipid screening guidelines for children overly aggressive, UCSF researchers say
5. BUSM researchers identify genetic markers for testosterone, estrogen level regulation
6. UGA researchers develop rapid diagnostic test for pathogens, contaminants
7. Moffitt Cancer Center researchers find potential key to new treatment for mantle cell lymphoma
8. Researchers link Kawasaki Disease in childhood with increased risk of adult heart disease
9. Researchers to use novel metabolomics technology for COPD
10. Researchers hit back at early bodycheck theory
11. Cleveland Clinic researchers discover molecule that may prevent atherosclerosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... WEDNESDAY, Aug. 20, 2014 (HealthDay News) -- Leaving the car ... public transit is good for your health, a new study ... United Kingdom and found that 76 percent of men and ... men and 11 percent of women used public transit, and ... or walked. Those who drove to work weighed more ...
(Date:8/20/2014)... According to a new market ... SPD, Liquid Crystal, Microblinds, Thermographic and Photochromics), by ... others), by geography - Global Forecast to 2014 ... Smart glass market was worth $1581.4 Million in ... by 2020, at an estimated CAGR of 20% ...
(Date:8/20/2014)... Raleigh, NC (PRWEB) August 20, 2014 Doctors ... a way to wipe out mesothelioma in laboratory mice by ... Mesothelioma has just posted details of the study on its ... , Scientists with Hong Kong University’s AIDS Institute of ... death protein 1” or PD-1. By altering DNA, the vaccine ...
(Date:8/20/2014)... New Jersey’s Medical Marijuana Program has ... tens of thousands of patients in the state. However, ... that would expand the list of qualifying conditions and ... summer by State Assemblywoman Linda Stender, the need to ... growing. , To help fill the information gap for ...
(Date:8/20/2014)... OR (PRWEB) August 20, 2014 August ... are urged to become educated about eye health and ... examined. One frequently overlooked eye condition that must be ... Sharon Kleyne Hour Power of Water radio show, is ... children increasing exponentially, childhood dry eye is becoming a ...
Breaking Medicine News(10 mins):Health News:Want to Stay Slim? Leave the Car at Home 2Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 2Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 3Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 4Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 5Health News:New Research Study Finds Vaccine Stops Mesothelioma in Lab Mice, According to Surviving Mesothelioma Website 2Health News:Oaksterdam University to Host Four-Day Educational Marijuana Horticultural Seminar Aug 23-26; Training Fills Information Gap for Medical Marijuana Caregivers and Patients 2Health News:Oaksterdam University to Host Four-Day Educational Marijuana Horticultural Seminar Aug 23-26; Training Fills Information Gap for Medical Marijuana Caregivers and Patients 3Health News:August is Children’s Eye Health Month, Exams Must Check for Pediatric Dry Eye 2Health News:August is Children’s Eye Health Month, Exams Must Check for Pediatric Dry Eye 3
... painkillers to treat inflammation are linked to an increased ... or flutter), concludes a study published on bmj.com ... drugs (NSAIDS) as well as new generation anti-inflammatory drugs, ... already been linked to an increased risk of heart ...
... Dennis Thompson HealthDay Reporter , SUNDAY, July 3 (HealthDay ... the summer air with dazzling colors and deafening sounds. But they ... year are harmed by fireworks, many of them maimed for life, ... care. "Where we see injuries is a lack of common ...
... N.C. July 4, 2011 Smoking cigarettes is a ... the smokers who choose to use one of the most ... the risk of serious cardiovascular events are on their way. ... Baptist Medical Center, in collaboration with researchers at Johns Hopkins ...
... Reinberg HealthDay Reporter , FRIDAY, July 1 (HealthDay ... are endorsing a U.S. health advisory panel,s recommendation that the ... breast cancer. The reason: There,s still a lack of ... Avastin was given fast-track approval by the U.S. ...
... The children most likely to walk or cycle to ... in an economically disadvantaged home, according to survey results that ... Pabayo of the University of Montreal Hospital Research Centre and ... is unique in that it follows the same group of ...
... the international aid community started to fund health programs ... support for tackling infectious diseases, and for implementing immunization ... and by governments are not always the same. New ... Globalization and Health uses ,agency theory, to examine ...
Cached Medicine News:Health News:Common painkillers linked to irregular heart rhythm 2Health News:Safety Experts Warn of Fireworks Dangers 2Health News:Safety Experts Warn of Fireworks Dangers 3Health News:Safety Experts Warn of Fireworks Dangers 4Health News:Chantix associated with 72 percent increased risk of serious CV events 2Health News: Avastin Rejection Supported by Cancer Experts 2Health News: Avastin Rejection Supported by Cancer Experts 3Health News: Avastin Rejection Supported by Cancer Experts 4Health News:Urban children are healthier commuters than rural teens 2Health News:Getting aid to where it is needed 2
(Date:8/19/2014)... , Aug. 19, 2014  Boehringer Ingelheim today ... (FDA) accepted for review the New Drug Application ... and olodaterol delivered via the Respimat ® ... maintenance treatment of airflow obstruction in patients with ... and/or emphysema. Tiotropium + olodaterol FDC will not ...
(Date:8/19/2014)... -- According to Kalorama Information, electronic medical records (EMR) ... in healthcare a reality, and this a factor that ... Recovery and Reinvestment Act, the U.S. government dedicated $20.6 ... will start applying soon for use of paper records.  ... of the EMR industry, EMR 2014: The Market ...
(Date:8/19/2014)... Calif. , Aug. 19, 2014  Cardiva Medical, ... two tranches of a $16.5 million Series 3 private ... with GE Capital. The Company will use the proceeds ... facility to expand commercial efforts for its VASCADE® Vascular ... . Investing in Series 3 private ...
Breaking Medicine Technology:Boehringer Ingelheim Announces U.S. Filing for the Fixed-Dose Combination Tiotropium Plus Olodaterol for Patients with COPD 2Boehringer Ingelheim Announces U.S. Filing for the Fixed-Dose Combination Tiotropium Plus Olodaterol for Patients with COPD 3Boehringer Ingelheim Announces U.S. Filing for the Fixed-Dose Combination Tiotropium Plus Olodaterol for Patients with COPD 4Boehringer Ingelheim Announces U.S. Filing for the Fixed-Dose Combination Tiotropium Plus Olodaterol for Patients with COPD 5Boehringer Ingelheim Announces U.S. Filing for the Fixed-Dose Combination Tiotropium Plus Olodaterol for Patients with COPD 6Boehringer Ingelheim Announces U.S. Filing for the Fixed-Dose Combination Tiotropium Plus Olodaterol for Patients with COPD 7Boehringer Ingelheim Announces U.S. Filing for the Fixed-Dose Combination Tiotropium Plus Olodaterol for Patients with COPD 8Kalorama: EMR Paves the Way for Big Data 2Kalorama: EMR Paves the Way for Big Data 3Cardiva Medical, Inc. Announces Completion of the first two tranches of Series 3 Private Equity Financing and the Closing of a Senior Secured Debt Facility with GE Capital 2
... The Stryker Inter-Lock™ System ... surgery at the tibial fixation ... backup fixation into one implant. ... and can be used routinely ...
The Stryker Bioabsorbable Wedge Interference Screw is made of Poly-L Lactic Acid (PLLA). The patented wedge design makes it perfect for cruciate reconstruction and is indicated for BTB and soft tissu...
The Stryker Graft Workstation offers the surgeon flexibility in graft preparation. The posts are interchangeable and the system adapts to both soft tissue and bone grafts selection. Sizing gauges off...
... Medicine Knot Pusher is a reusable instrument used ... Knot Pusher is utilized in the handling and ... two piece shaft allows the surgeon to place ... pushing. The ring handle allows the surgeon ease ...
Medicine Products: