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Researchers study potential health benefits of natural chemicals in muscadine grape seeds
Date:10/24/2007

WINSTON-SALEM, N.C. Could some of the natural chemicals found in plants be powerful enough to improve cardiovascular health" Researchers at Wake Forest University Baptist Medical Center are conducting the first-ever clinical study to evaluate the potential cardiovascular health effects of Natures Pearl Muscadine Grape Seed Supplement.

The scientists are evaluating the influence of this supplement on blood vessel function in 50 participants who have cardiovascular disease or are at high risk for developing it. Theyll also determine whether there are effects on cholesterol and other fats in the blood, blood sugar levels and vessel inflammation, which are all associated with increased risk of cardiovascular disease.

Natures Pearl is prepared in a way that generates a high concentration of plant chemicals, including gallic acid, ellagic acid, oligomeric proanthocyanidins (OPCs) and resveratrol. These are known to be antioxidants, or nutrients that can prevent or slow the oxidative damage to the body. The role of oxidative stress in blood vessel disease has generated interest in dietary sources of antioxidants, including black and green tea, grape seeds, olive oil and cocoa.

Muscadine grapes have been shown to be more potent in antioxidants than any other variety of grapes, and laboratory studies have suggested that grape seeds have higher antioxidant capacity than grape skins. Studies in humans have shown improved antioxidant capacity when grape seed supplement is added to the diet, as well as improvements in blood vessel function. However, the studies did not specifically include muscadine grapes, which have extremely high levels of antioxidant and anti-inflammatory compounds when compared to other fruits.

The goal of the current study is to determine if daily doses of the Natures Pearl supplement, which is specially prepared to maximize its natural antioxidant and anti-inflammatory concentrations, will have a favorable effec
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Contact: Karen Richardson
krchrdsn@wfubmc.edu
336-716-4453
Wake Forest University Baptist Medical Center
Source:Eurekalert

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