Navigation Links
Researchers review studies on CCSVI-MS link

TORONTO, Ont., Oct. 3, 2011Studies that examined the possible link between vein blockages and multiple sclerosis are so inconsistent that it's impossible to reach a firm conclusion about the controversial theory, a new review has found.

Overall, the studies found the blockages known as chronic cerebrospinal venous insufficiency, or CCSVI, are found more often in people who have MS than those who do not.

But a team of researchers and physicians lead by Dr. Andreas Laupacis of St. Michael's Hospital in Toronto said more research was needed.

Italian Dr. Paola Zamboni has suggested that MS may be caused by blockages in the veins in the neck, causing iron deposition in the brain, which triggers an autoimmune reaction. He proposed that unblocking the veins by mechanically widening them improves the symptoms of MS.

Canadian researchers analyzed eight published studies carried out in the United States, Germany, Italy and Japan that used ultrasound to diagnose CCSVI and compared MS patients with non-MS patients.

They found the quality of the studies varied and there were large differences in the results. In general, the studies were small and had incomplete descriptions of the training of those conducting the ultrasounds. None of them reported the degree to which the people conducting the ultrasounds knew whether the subject was an MS patient. Some of the studies found no difference in the frequency of CCSVI between MS and non-MS patients while others found large differences.

When the results of all the studies were combined statistically, CCSVI was found more frequently in those with MS than those who did not have it.

The analysis of the studies was financed by the Canadian Institutes of Health Research. Portions of the study were published today in the Canadian Medical Association Journal.

Dr. Laupacis, executive director of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, said there is great controversy over whether CCSVI causes MS and people on both sides of the issue tend to focus on the research that supports their position and ignore research that supports the other. That's why his team conducted a review of all studies that met certain quality standards.

"The differences among published studies means we can't be definitive at the present time," said Dr. Laupacis, "The overall findings suggest that there may be an association between CCSVI and MS. However, the differences among study results and the poor quality of some of the studies means that more research still needs to be done."

Dr. Laupacis said even if CCSVI is found to be more common in MS patients, that doesn't mean CCSVI causes MS; it may be that MS causes CCSVI.


Contact: Leslie Shepherd
St. Michael's Hospital

Related medicine news :

1. Researchers call for more awareness of male breast cancer as cases rise
2. Researchers transform iPhone into high-quality medical imaging device
3. Fox Chase researchers identifiy more accurate treatment delivery for robotic radiosurgery system
4. Georgia Tech researchers receive 3 NSF Emerging Frontiers awards
5. Childrens National researchers make breakthrough in understanding white matter development
6. UH researchers explain hormonal role in glucose and fat metabolism
7. Researchers identify enzyme that regulates degradation of damaged proteins
8. UTHealth researchers train promotoras to combine mobile technology, cancer prevention messages
9. Researchers uncover gene associated with blood cancers
10. Boston researchers share in $10 million grant to study HIV and alcohol
11. Rhode Island Hospital researchers find possible cardiovascular risk with NSAID use
Post Your Comments:
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, ... treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including robotic ... osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It ...
(Date:6/24/2016)... NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin ... companies that call for a minimum wage raise to $12 an hour by 2020 and ... This will restore the lost value of the minimum wage, assure the wage floor does ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine presented ... in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor the ... Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With this award, ...
(Date:6/24/2016)... Vegas, Nevada (PRWEB) , ... June 24, 2016 ... ... Las Vegas client, The Grove Investment Group (TGIG), has initiated cultivation and processing ... Grove, in Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of ...
(Date:6/24/2016)... ... 24, 2016 , ... National recruitment firm Slone Partners is pleased ... and genomics experience, as Vice President of North American Capital Sales at HTG ... leading the sales team in the commercialization of the HTG EdgeSeq system and associated ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... India , June 24, 2016 ... Needles Market by Type (Standard Pen Needles, Safety Pen ... Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, ... by MarketsandMarkets, This report studies the market for the ... expected to reach USD 2.81 Billion by 2021 from ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... - Forecast to 2022" report to their offering. ... for the patients with kidney failure, it replaces the function ... the patient,s blood and thus the treatment helps to keep ... in balance. Increasing number of ESRD patients ...
Breaking Medicine Technology: