Navigation Links
Researchers review studies on CCSVI-MS link
Date:10/3/2011

TORONTO, Ont., Oct. 3, 2011Studies that examined the possible link between vein blockages and multiple sclerosis are so inconsistent that it's impossible to reach a firm conclusion about the controversial theory, a new review has found.

Overall, the studies found the blockages known as chronic cerebrospinal venous insufficiency, or CCSVI, are found more often in people who have MS than those who do not.

But a team of researchers and physicians lead by Dr. Andreas Laupacis of St. Michael's Hospital in Toronto said more research was needed.

Italian Dr. Paola Zamboni has suggested that MS may be caused by blockages in the veins in the neck, causing iron deposition in the brain, which triggers an autoimmune reaction. He proposed that unblocking the veins by mechanically widening them improves the symptoms of MS.

Canadian researchers analyzed eight published studies carried out in the United States, Germany, Italy and Japan that used ultrasound to diagnose CCSVI and compared MS patients with non-MS patients.

They found the quality of the studies varied and there were large differences in the results. In general, the studies were small and had incomplete descriptions of the training of those conducting the ultrasounds. None of them reported the degree to which the people conducting the ultrasounds knew whether the subject was an MS patient. Some of the studies found no difference in the frequency of CCSVI between MS and non-MS patients while others found large differences.

When the results of all the studies were combined statistically, CCSVI was found more frequently in those with MS than those who did not have it.

The analysis of the studies was financed by the Canadian Institutes of Health Research. Portions of the study were published today in the Canadian Medical Association Journal.

Dr. Laupacis, executive director of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, said there is great controversy over whether CCSVI causes MS and people on both sides of the issue tend to focus on the research that supports their position and ignore research that supports the other. That's why his team conducted a review of all studies that met certain quality standards.

"The differences among published studies means we can't be definitive at the present time," said Dr. Laupacis, "The overall findings suggest that there may be an association between CCSVI and MS. However, the differences among study results and the poor quality of some of the studies means that more research still needs to be done."

Dr. Laupacis said even if CCSVI is found to be more common in MS patients, that doesn't mean CCSVI causes MS; it may be that MS causes CCSVI.


'/>"/>

Contact: Leslie Shepherd
shepherdl@smh.ca
416-864-6094
St. Michael's Hospital
Source:Eurekalert

Related medicine news :

1. Researchers call for more awareness of male breast cancer as cases rise
2. Researchers transform iPhone into high-quality medical imaging device
3. Fox Chase researchers identifiy more accurate treatment delivery for robotic radiosurgery system
4. Georgia Tech researchers receive 3 NSF Emerging Frontiers awards
5. Childrens National researchers make breakthrough in understanding white matter development
6. UH researchers explain hormonal role in glucose and fat metabolism
7. Researchers identify enzyme that regulates degradation of damaged proteins
8. UTHealth researchers train promotoras to combine mobile technology, cancer prevention messages
9. Researchers uncover gene associated with blood cancers
10. Boston researchers share in $10 million grant to study HIV and alcohol
11. Rhode Island Hospital researchers find possible cardiovascular risk with NSAID use
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2017)... ... ... Curl Keeper® is excited to announce that the H2O Water Bottle is the ... second year in a row. The H2O Bottle, a refillable ultra-fine spray water bottle ... Type 2 Wavies and Best Refresher for Type 2 Wavies in 2017. , ...
(Date:8/19/2017)... , ... August 19, 2017 , ... “Congratulations! It's A ... of children to both their parents and God. “Congratulations! It's A Boy! God’s Gift: ... Anthony, a couple from Long Island, New York. , Published by Christian Faith Publishing, ...
(Date:8/18/2017)... NY (PRWEB) , ... August 18, 2017 , ... ... of “Vision & Hearing” campaign, advocating for active, healthy lifestyles and highlighting the ... available for individuals with hearing impairments and shares the latest innovations in hearing ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... financial consultations to communities throughout the greater DC region, is inaugurating a “New ... of rescuing local animals and training them to be companions for veterans in ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... firm that serves residential and commercial clients in the greater Houston region, is ... community support for the fight against cancer. , Founded by Tony and Amber ...
Breaking Medicine News(10 mins):
(Date:7/31/2017)... July 31, 2017  Diplomat Pharmacy, Inc. (NYSE: DPLO), has ... Michigan by Crain,s Detroit Business . ... public companies by three-year revenue growth. This year,s edition measures ... To view the complete list, visit crainsdetroit.com/awards/fast_50/2017 .  ... an incredible triumph," said Phil Hagerman , CEO and ...
(Date:7/31/2017)... 2017 7D Surgical, developer of ground breaking surgical ... 7D Surgical System to support its strategic sales plan in ... and Virginia.  7D Surgical has entered into an exclusive ... premier medical facilities within those markets. ... Spartan Medical ...
(Date:7/28/2017)... 28, 2017 EnvoyHealth, a Diplomat company, has partnered ... for CleverCap LITE, a technology designed to improve patient ... innovative health technology solutions and services that help track ... CleverCap LITE offers medication monitoring and control ... Records date and ...
Breaking Medicine Technology: