Navigation Links
Researchers reveal most effective treatment for common kidney disorder
Date:1/9/2013

The results of a pioneering UK-wide clinical trial that compared treatments for patients with a common type of kidney disease has found one to be significantly more effective. The results of the study, published online in The Lancet today [9 Jan], will be recommended to clinicians worldwide as the most effective approach to treating the condition.

The Medical Research Council-funded study, led by researchers from the University of Bristol's Academic Renal Unit based in Southmead Hospital, compared three treatment approaches in a type of kidney disorder known as 'membranous nephropathy'.

The condition, which leads to changes and inflammation of the structures inside the kidney that help filter wastes and fluids, is usually managed with immunosuppressive drugs but has a high risk of causing kidney failure in patients. Previous studies of the disorder, which is costly to treat (kidney failure treatments cost $40 billion in the US in 2008), show that once kidney function starts to decline, continued deterioration can be expected.

The research team, led by Professor Peter Mathieson, Dean of the Faculty of Medicine and Dentistry, carried out a randomised controlled trial involving 108 patients with 20 per cent decline in renal function at 37 renal units across the UK. The patients were randomised to one of three treatment approaches and followed up by the team over three years.

The team evaluated results from 33 patients who were treated with prednisolone and chlorambucil, 37 patients with ciclosporin and 38 who were provided with supportive therapy alone.

They found that for patients with membranous nephropathy, six months' therapy with alternating monthly cycles of prednisolone and chlorambucil was the most effective option. This approach was shown to be the most effective in preventing further renal decline in patients with the benefits maintained over the three-year study period and thus the recommended treat
'/>"/>

Contact: Caroline Clancy
caroline.clancy@bristol.ac.uk
44-011-792-88086
University of Bristol
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers identify new target for common heart condition
2. USF and VA researchers find long-term consequences for those suffering traumatic brain injury
3. Pesticides and Parkinsons: UCLA researchers uncover further proof of a link
4. Mayo Clinic researchers find new molecule to target in pancreatic cancer treatment
5. Researchers zero in on cognitive difficulties associated with menopause
6. Common data determinants of recurrent cancer are broken, mislead researchers
7. Researchers identify an early predictor for glaucoma
8. PolyU Researchers Develop Novel Treatment for People with Hemiplegic Arms
9. A Serious Problem: Medical Malpractice Lawyers at Console & Hollawell React to Alarming Doctor Error Statistics from Johns Hopkins University Researchers
10. U of T Researchers uncover major source of evolutionary differences among species
11. MRIs reveal signs of brain injuries not seen in CT scans, UCSF/SFGH researchers report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... ... 2015 , ... Ticket Down is a reputable source of authentic Kid Rock tickets at ... is hitting the road again this summer in what is one of the most affordable ... his summer tour this year at the XFINITY Theatre in Hartford, CT on June 24th ...
(Date:6/30/2015)... Provo, UT (PRWEB) , ... June 30, 2015 , ... Ticket Down is a reliable ... LaVell Edwards Stadium in Provo, Utah. This legendary band has been packing venues for ... years. They have also released more than 20 albums in their career. While Journey ...
(Date:6/30/2015)... ... ... The American Institute of Personal Injury Attorneys (AIOPIA) awarded JTB Law Group, LLC as a ... Award respectively. As of July 1, 2015, the firm and Mr. Brown personally have ... Jersey. The award is a culmination of the hard work, long hours, and excellent ...
(Date:6/30/2015)... ... ... According to research by European archeologists that was recently discussed in a ... thousand years ago likely knew that eating a balanced diet and limiting smoke inhalation ... plaque, researchers were able to find evidence of plant fibers, in addition to the ...
(Date:6/30/2015)... (PRWEB) , ... June 30, 2015 , ... ... first UHMS approved 40-hour Introduction to Hyperbaric Medicine Course. Clinicians from WCA partnering ... of hyperbaric medicine curriculum. , Wound care and hyperbaric medicine education and ...
Breaking Medicine News(10 mins):Health News:Cheap Kid Rock Tickets at the DTE Energy Music Theatre in Clarkston: Ticket Down Has Slashed Prices On All Kid Rock Tickets at DTE in the Detroit Metro Area 2Health News:Journey Tickets at The Stadium of Fire at Lavell Edwards Stadium in Provo, Utah: Ticket Down Slashes Ticket Prices for Journey on the 4th of July in Provo 2Health News:JTB Law Group, LLC Recognized as a Top 10 Best Law Firm by AIOPIA 2Health News:Recent Article Detailing Research on 400,000 Year Old Dental Plaque Shows Ancestral Understanding of Healthy Eating and Basic Oral Hygiene, Says Feiz Dental 2Health News:Recent Article Detailing Research on 400,000 Year Old Dental Plaque Shows Ancestral Understanding of Healthy Eating and Basic Oral Hygiene, Says Feiz Dental 3Health News:Wound Care Advantage Hosts Its First UHMS Approved 40-Hour Introduction to Hyperbaric Medicine Course 2Health News:Wound Care Advantage Hosts Its First UHMS Approved 40-Hour Introduction to Hyperbaric Medicine Course 3
... form an integral part of most of,original equipment ... service providers in the European medical imaging services,market ... and,contract penetration rates. , ... New analysis ...
... Dec. 2 The Healthcare group at,Frost & Sullivan ... be hosting a free webinar on the medical insurance ... CAT/14h00 GMT. , ... Medical insurance as a means of financing ...
... 3, Mercy Ships celebrates with the story of a young boy born ... floating hospital docked in Liberia, Benedict,s feet are corrected now and he ... High resolution photos and video can be downloaded at www.mercyshipsnewsroom.org ... ...
... and Fire Safety Tips for Busy Moms at www.BeFireSmart.com ... ... and Holly Robinson Peete , actress, philanthropist and mother of ... moments before the holiday rush to review fire safety precautions and response ...
... tomography (CT) colonography, also known as virtual colonoscopy, has the ... osteoporosis, both of which commonly affect adults over age 50. ... annual meeting of the Radiological Society of North America (RSNA). ... colonography, in addition to screening for colorectal cancer, we were ...
... reveals that computed tomography (CT) colonography, also known as ... diseases at oncecolorectal cancer and osteoporosis, both of which ... study will be presented today at the annual meeting ... "With CT colonography, in addition to screening for colorectal ...
Cached Medicine News:Health News:Encouraging Prospects for Medical Imaging Equipment Services in Europe 2Health News:Encouraging Prospects for Medical Imaging Equipment Services in Europe 3Health News:The Future of Financing Health Services in Africa 2Health News:Mercy Ships Recognizes International Day of Disabled Persons 2Health News:Mercy Ships Recognizes International Day of Disabled Persons 3Health News:Liberty Mutual and Holly Robinson Peete Team Up to Remind Families to Be Fire Smart this Holiday Season with Tips on Fire Safety 2Health News:Liberty Mutual and Holly Robinson Peete Team Up to Remind Families to Be Fire Smart this Holiday Season with Tips on Fire Safety 3Health News:Liberty Mutual and Holly Robinson Peete Team Up to Remind Families to Be Fire Smart this Holiday Season with Tips on Fire Safety 4Health News:CT Colonography Offers One-Stop Screening for Cancer and Osteoporosis 2Health News:CT Colonography Offers One-Stop Screening for Cancer and Osteoporosis 3Health News:CT colonography offers 1-stop screening for cancer and osteoporosis 2
(Date:6/30/2015)... /PRNewswire/ – Small Cap IR issues report. Recently, Arrayit ... Arrayit blood card technology to Vivos, Global Genome Vault, ... offers an impervious, impenetrable and permanent DNA storage vault, ... on Earth, a safe and secure nuclear blast-proof, underground ... the rapid collection, separation, drying and storage of human ...
(Date:6/30/2015)... , June 30, 2015  Egalet Corporation ... integrated specialty pharmaceutical company focused on developing, ... announced top-line results from a Category 3 ... an abuse-deterrent, extended-release, oral oxycodone product candidate ... of pain severe enough to require daily, ...
(Date:6/30/2015)... 2015 PharmaVentures is pleased to ... Technologies Oy (CMT) on its divestment of certain assets ... CMTs world leading capabilities in cellular imaging and analysis. ... series of successful global deals in the life science ... Fintan Walton , CEO, PharmaVentures, commented: "PharmaVentures is delighted ...
Breaking Medicine Technology:Small Cap IR - Empowering the Age of Genetic Enlightenment 2Egalet Announces Top-Line Results from Oral Human Abuse Liability Study of Egalet-002 2Egalet Announces Top-Line Results from Oral Human Abuse Liability Study of Egalet-002 3Egalet Announces Top-Line Results from Oral Human Abuse Liability Study of Egalet-002 4Egalet Announces Top-Line Results from Oral Human Abuse Liability Study of Egalet-002 5PharmaVentures Completes M&A Deal for Technology in the Stem Cell & Regenerative Medicine Sector 2
Telescopic Diamond-Dissectors for delicate sharp tissue preparation. Total/working lengths 220/240 mm with protective sleeve....
Epstein Curettes 3.0 mm, length 8" (203 mm)....
Cobb Spinal Curettes, tip size 13.00 mm, length 11" (279 mm)....
Karlin XL Magnum Ring Curettes, extra long (XL) curettes, black handles, lightweight. Length 13 1/4" (33.7 cm), handle length 8 1/2" (21 cm), handle diameter 1 1/4" (32 cm)....
Medicine Products: