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Researchers report no difference in breast cancer characteristics after oophorectomy
Date:5/28/2010

tive environment of an oophorectomy, we don't expect their cancer will be any better or worse than that of a woman who didn't have an oophorectomy," Nitzkorski says.

To evaluate the impact of ovary removal on breast cancers, the team identified 687 women diagnosed with invasive breast cancer between 2004 and 2008 at Fox Chase and who had a known ovary status. Of these, 71 (10.3%) had undergone a prior bilateral oophorectomy. The women who had had their ovaries removed were significantly more likely to have taken hormone replacement therapy than women who still had their ovaries, 56.3% versus 19.0%.

Tumors in the women who had undergone a bilateral oophorectomy were smaller than those in women who had their ovaries, with a median of 1.3 cm compared with 1.5 cm, which was a statistically significant difference. Additionally, mammographic detection was more common in women who had had their ovaries removed than in women with their ovaries, 69.0% compared with 47.9%, respectively. Although patient's cancer tumor and lymph node staging was accounted for, Nitzkorski and colleagues have not seen any difference in overall survival related to oophorectomy with in their 20 months of follow up


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Contact: Diana Quattrone
Diana.Quattrone@fccc.edu
215-728-7784
Fox Chase Cancer Center
Source:Eurekalert

Page: 1 2

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