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Researchers report benefits of new standard treatment study for rare pediatric brain cancer
Date:10/9/2009

earch, which originally showed the significant advantage of complete surgical resection. The SIOP 2000 study found that patients receiving the intense chemotherapy protocol had similar outcomes as those with complete resection, reducing the need for surgical treatment.

"We think the better outcomes had to do with the fact that physicians will prolong chemotherapy treatment if there is residual tumor," said Wolff. "If we can prove this hypothesis, this would be an argument for extending treatment in the future."

Wolff says the next step will be to begin another study that will investigate a four-armed chemotherapy protocol. This would investigate the possibility of adding another chemotherapy to further improve survival rates. The SIOP 2000 study used carboplatinum, etoposide and cyclophosamide in combination with radiation.


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Contact: Sara Farris
sfarris@mdanderson.org
713-792-9133
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert

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