Navigation Links
Researchers publish one of the longest longitudinal studies of cognition in MS
Date:6/24/2014

Researchers at Kessler Foundation and the Cleveland Clinic have published one of the longest longitudinal studies of cognition in multiple sclerosis (MS). The article, "Cognitive impairment in multiple sclerosis: An 18-year follow-up study," (DOI: 10.1016/j.msard.2014.03.004) was epublished by Multiple Sclerosis and Related Disorders on April 13, 2014. Results provide insight into the natural evolution of cognitive changes over time, an important consideration for researchers and clinicians. Authors are Lauren B. Strober, PhD, of Kessler Foundation and Stephen M. Rao, PhD, Jar-Chi Lee, Elizabeth Fisher, PhD, and Richard Rudick, MD, of the Cleveland Clinic.

"While cognitive impairment is known to affect 40 to 65% of individuals with MS, few studies have followed the pattern of cognitive decline over time, which is important for understanding long-term care and outcomes associated with MS," said Dr. Strober, senior research scientist at Kessler Foundation. "Our study was based on a unique sample of 22 patients who underwent neuropsychological testing at entry into the original phase 3 clinical trial of intramuscular interferon beta-1a, and again at 18-year followup."

At baseline, 9 patients (41%) had cognitive impairment; at 18-year followup, 13 patients (59%), were found to be impaired. Significant declines over time were found in information processing speed, auditory attention, memory, episodic learning and visual construction. Decline was steeper in the unimpaired than in the impaired group, as indicated by the Symbol Digit Modalities Test (SDMT).

"These longitudinal data contribute substantially to our knowledge of the course of cognitive decline in MS," noted John DeLuca, PhD, VP of Research & Training at Kessler Foundation. "In light of the young age at diagnosis, this perspective is fundamental to the development of rehabilitation strategies that meet the needs of people dealing with the cognitive effects of MS."


'/>"/>

Contact: Carolann Murphy
cmurphy@kesslerfoundation.org
973-325-8382
Kessler Foundation
Source:Eurekalert  

Related medicine news :

1. SLU researchers see possible answer to chemo pain in a multiple sclerosis drug
2. Miriam Hospital researchers analyze AUDs, sexual behavior among South African men
3. Researchers find gene critical for development of brain motor center
4. New target: Researchers identify pancreatic cancer resistance mechanism
5. U of MD researchers receive NIH grant to study personalized medicine for genetic diabetes
6. Researchers map genomic differences in yellow fever, malaria mosquitoes
7. Researchers identify mechanism that could help old muscle grow
8. Researchers identify new compound to treat depression
9. Researchers create better methods to detect E. coli
10. UGA researchers discover new method to reduce disease-causing inflammation
11. Ottawa researchers key to new neuromuscular disease care and research network
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers publish one of the longest longitudinal studies of cognition in MS
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... ... educational training program owned and organized by HMP Communications Holdings, LLC, today announced ... for physicians within its nationwide network of wound centers interested in becoming Certified ...
(Date:3/23/2017)... ... 2017 , ... After raising more than $1.135 million ($1,479,231 AUD) from nearly ... in crowdfunding history, has established a U.S. Headquarters in New York City, FaceCradle ... , “We’re excited to be operating on U.S. shores, where most of our initial ...
(Date:3/23/2017)... Grants Pass, OR (PRWEB) , ... March 23, 2017 , ... ... Power of Water, Global Climate Change and Your Health on VoiceAmerica, recently talked on ... 22nd, but she also used the occasion to remind listeners of an important distinction. ...
(Date:3/23/2017)... , ... March 23, 2017 , ... Inflow IQ & ... is serious so build on a solid foundation. As experts in dangerous situations ... information that is coming soon. Inflownomics deliver ripe, fresh, clean & refreshing knowledge systems ...
(Date:3/23/2017)... ... March 23, 2017 , ... The founders of Dr. Wang ... winners of American Dreams & Good Housekeeping Seal Initiative, a nationwide search for ... Good Housekeeping. , Steven Wang, MD ., a renowned dermatologist and medical ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... 23, 2017 The Board of Directors of ... General Meeting, which is to take place on Thursday, April 27, ... Lund, Sweden . ... Please see the attached notification, which is being announced ... NeuroVive Pharmaceutical AB (Publ) The Board Of Directors ...
(Date:3/22/2017)... Research and Markets has announced the addition of the ... Forecast to 2025" report to their offering. ... The Global Respiratory care devices ... over the next decade to reach approximately $38.27 billion by 2025. ... forecasts for all the given segments on global as well as ...
(Date:3/22/2017)... , March 22, 2017 Ampio ... the development of Ampion™, a low molecular weight ... today announced that it is re-issuing its previous release ... incorporate certain disclosures that are required under the ... below are these additional disclosures along with the ...
Breaking Medicine Technology: