Navigation Links
Researchers publish molecular disease model for melanoma
Date:3/30/2011

Cancer Commons, an initiative of CollabRx, a provider of information technology to personalize cancer treatments and accelerate research, announces the publication of a molecular disease model of melanoma (MDMM) which classifies the disease into molecular subtypes, rather than traditional histological or cellular subtypes, and describes treatment guidelines for each subtype, including specific assays, drugs, and clinical trials. The paper, titled "Molecular Disease Model for Melanoma," by Vidwans et al, was published in the March 30th issue of PLoS ONE.

Published as a "dynamic" review paper by a panel of leading researchers and clinicians affiliated with the Cancer Commons initiative, the MDMM is maintained online, curated by the authors and continuously updated based on input from the melanoma community to reflect the latest scientific, clinical and technological advancements in cancer research and treatment. The MDMM is designed as an interface between the research and clinical communities where researchers can learn from clinical outcomes to refine molecular subtypes and clinicians can use the latest subtype information in treatment decisions. In this way, the online melanoma disease model becomes the core of an adaptive, rapid learning community that provides each patient with the best possible outcome while aggregating results over all patients to advance the standard of care.

The MDMM consists of a set of "actionable" molecular subtypes and proposed practice guidelines for treating each subtype: which therapies (approved or experimental) should be considered and which are contraindicated. A molecular subtype of melanoma is loosely defined as those tumors containing the same set of molecular (primarily genetic) defect(s) and their associated pathways. A subtype is deemed actionable if there is both a CLIA-approved assay to determine whether a given tumor fits that classification, and at least one FDA-approved or experimental target
'/>"/>

Contact: Jen Laloup
jlaloup@plos.org
415-624-1220
Public Library of Science
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Researchers find possible clues to tamoxifen resistance in breast cancer patients
2. UCSF researchers identify promising new treatment for childhood leukemia
3. Researchers make the leap to whole-cell simulations
4. Stepchildren relate to stepparents based on perceived benefits, researchers find
5. Researchers find many elderly men are undergoing unnecessary PSA screenings
6. AACR and Landon Foundation support the next generation of researchers with INNOVATOR Awards
7. Can you hear me now? Researchers detail how neurons decide how to transmit information
8. AACR honors eminent researchers
9. Penn researchers uncover novel immune therapy for pancreatic cancer
10. Researchers: Sexually active teens need confidential health care
11. Researchers develop a halometer that tests alterations in night vision
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... ... July 02, 2015 , ... The ZAC Foundation, a ... swim season with important lessons on how to stay water safe with the help ... Wouldn’t Swim, authored by The ZAC Foundation co-founders, follows Zeke’s water safety journey. ...
(Date:7/2/2015)... ... July 02, 2015 , ... ... today that it has reached an agreement to acquire eRubbermaid.com, an Internet ... distributor of Rubbermaid Commercial Products on the web today. , ...
(Date:7/2/2015)... (PRWEB) , ... July 02, 2015 , ... ... Research (CVR) recently received nearly $4 million through five federal grants to ... vaccines and therapies against the deadly diseases. , The research will be ...
(Date:7/2/2015)... ... July 02, 2015 , ... B. E. ... been retained to lead a national chief operating officer recruitment for ... in the healthcare industry, B. E. Smith has recently placed more than 1,000 ...
(Date:7/2/2015)... ... 2015 , ... Evolved Ayurvedic Discoveries , Inc. (EAD ... to partner with companies that share a similar mission of providing the most ... Cannabidiol (CBD) formulations, combined with Ayurvedic herbs, are now available for wholesale, private ...
Breaking Medicine News(10 mins):Health News:The ZAC Foundation Kicks Off Summer and July 4th Weekend with Complimentary Children’s E-Book on Water Safety 2Health News:The ZAC Foundation Kicks Off Summer and July 4th Weekend with Complimentary Children’s E-Book on Water Safety 3Health News:CleanItSupply.com Acquires eRubbermaid.com 2Health News:Mosquito-Borne Viruses Subject of $4M in Federal Grants to Scientists in Pitt’s Center for Vaccine Research 2Health News:Mosquito-Borne Viruses Subject of $4M in Federal Grants to Scientists in Pitt’s Center for Vaccine Research 3Health News:Mosquito-Borne Viruses Subject of $4M in Federal Grants to Scientists in Pitt’s Center for Vaccine Research 4Health News:Nicklaus Children’s Hospital Retains B. E. Smith to Recruit New Chief Operating Officer 2Health News:Nicklaus Children’s Hospital Retains B. E. Smith to Recruit New Chief Operating Officer 3Health News:New Water Soluble CBD Provides Manufacturers & Distributors a More Effective, Safe, & Cost Efficient Alternative to Traditional CBD Oil 2Health News:New Water Soluble CBD Provides Manufacturers & Distributors a More Effective, Safe, & Cost Efficient Alternative to Traditional CBD Oil 3
... The Lorillard Tobacco,Company today issued the following statement ... House Committee on Energy and Commerce that would force ... tobacco industry., "The Lorillard Tobacco Company opposes H.R. ... tobacco. While Lorillard fully supports,reasonable federal regulation of the ...
... Mobility Helps Courageous Texas Man Fight Illness and Enjoy ... Last,December, James Matthijetz was in the process of ... could fully celebrate, the,24-year-old felt his body stiffen while ... had a brain hemorrhage and a minor stroke from ...
... April 4, 2008 The Pacific,Heart, Lung & ... products and adequate funding for research on,asbestos-related diseases. ... currently referred to as the "committee print," is ... provide meaningful funding., Public health concerns should ...
... with 2008 National Public Health Week, April,7-13, ... J. Markey (D-Mass.) and Congresswoman Hilda L. Solis,(D-Calif.) ... and Global,Warming on today,s introduction of a resolution ... relationship between public health,and global warming., The ...
... Personal interventions cut no-show rates 30%, study finds ... new studies make the case that more personal ... of low-income and minority patients getting recommended screening ... current issue of Clinical Gastroenterology and Hepatology ...
... Global Action Board of Directors brings ,hands on, approach ... direction to achieving Global Action,s mission statement, BOSTON, ... Global,Action announces today the recent addition of Robert Hernreich ... of Edwards,Colorado and Las Vegas, Nevada officially took his ...
Cached Medicine News:Health News:The SCOOTER Store Donates Power Scooter to an Uninsured Young Father Battling Cancer 2Health News:The SCOOTER Store Donates Power Scooter to an Uninsured Young Father Battling Cancer 3Health News:Pacific Heart, Lung & Blood Institute Position on Ban Asbestos Legislation 2Health News:Pacific Heart, Lung & Blood Institute Position on Ban Asbestos Legislation 3Health News:Patient Navigators Boost Colon Screens in Urban Minorities 2Health News:Global Action Board of Directors Announces Addition of Newest Member, Robert Hernreich 2
(Date:7/2/2015)... 2015 BGI a annoncé aujourd,hui que ... l,ADN situé à Hong Kong ... of Pathologists  (Collège des pathologistes américains, ou CAP). ... Kong constituent le premier laboratoire clinique ... certification du CAP en Chine, car il satisfait ...
(Date:7/2/2015)... , July 2, 2015 Leading ... to capture critical product and market insights in ... benefits to employee-based studies, it is essential for ... own internal employees to capture critical business-related insights. ... benchmarking firm, Best Practices, LLC, most benchmarked companies ...
(Date:7/2/2015)... HOUSTON, TX and VANCOUVER , ... the "Company") (TSX-V: EPI) announced today that its common shares ... Capital Market ("NASDAQ") under the symbol "EPIX". ESSA ... Company will retain its listing on the TSX Venture Exchange ... the listing of the common shares on the NASDAQ, each ...
Breaking Medicine Technology:BGI obtient la certification du Collège des pathologistes américains (CAP) 2Leveraging Employee Insights to Produce Cutting-Edge Market Research 2ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 2ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 3ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 4
... provides fingertip ratchet disengagement allowing smooth, ratchet-free ... offers state-of-the-art quality in an instrument of ... durability. Low profile cutting tips allow access ... I instruments are available in just about ...
... The patented ratchet design provides fingertip ... ,The Series I Instrument program offers state-of-the-art ... profile, while maintaining strength and durability. Low ... in tight joint spaces. Series I instruments ...
... The patented ratchet design provides fingertip ratchet ... Series I Instrument program offers state-of-the-art quality ... while maintaining strength and durability. Low profile ... tight joint spaces. Series I instruments are ...
... A broad selection of procedurally specific ... and allow easy access to all ... variety of approaches.,Loop Handled Graspers feature ... holds tissue firmly without tearing or ...
Medicine Products: