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Researchers present new findings on cancer and gene therapy
Date:4/7/2011

WASHINGTON, April 7, 2011 DNA's role as the master blueprint of the cell means that even small sequence changes can have catastrophic consequences. For this reason, much of our understanding of cancer development comes from studying how cells copy DNA and repair sequence errors -- and how these processes can go wrong.

Next week, a thematic program at the American Society for Biochemistry and Molecular Biology's annual meeting at the Experimental Biology 2011 conference in Washington, D.C., will bring together researchers from across the country to discuss recent developments in DNA replication, recombination, and repair, and the importance of these activities in cancer and gene therapy. It will launch Sunday in Room 206 of the Walter E. Washington Convention Center.

Theme organizers Marlene Belfort from the Wadsworth Center at the New York State Department of Health and Joann B. Sweasy from Yale University have assembled a roster of experts who will present recent discoveries in how cells manage the process of copying DNA, adding and removing stretches of sequence in the genome, and the consequences of when mistakes occur.

Aberrant DNA Repair, Genomic Instability and Cancer: The first platform session will be held from 9:55 a.m. to 12:10 p.m. Sunday. Cells accumulate at least 20,000 DNA lesions a day that require repair to maintain healthy cellular function. Because maintaining a stable genome is crucial to preventing disease, research on aberrant DNA repair and other processes that alter DNA sequence are important aspects of understanding the development of cancer. This session will feature researchers from the University of Texas M.D. Anderson Cancer Center, Yale University and the Massachusetts Institute of Technology.

Site-Specific Recombination in Chromosome Dynamics and Gene Therapy: The second round of talks, to be held from 3:45 p.m. to 6 p.m. Monday, will focus on gene therapy, a promising area of rese
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Contact: Angela Hopp
ahopp@asbmb.org
301-634-7389
Federation of American Societies for Experimental Biology
Source:Eurekalert

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