Navigation Links
Researchers observe an increased risk of cancer in people with history of non-melanoma skin cancer
Date:4/23/2013

Boston, MA A prospective study by researchers at Brigham and Women's Hospital (BWH) observed an association between risk of second primary cancer and history of non-melanoma skin cancer in white men and women.

The researchers found that people with a history of non-melanoma skin cancer had a modestly increased risk of getting cancer in the future, specifically breast and lung cancer in women and melanoma in both men and women. Non-melanoma skin cancer, which includes basal cell and squamous cell carcinoma, is the most common form of cancer in the United States.

The study will be published on April 23, 2013 in PLOS Medicine.

The researchers analyzed data from two large United States cohort studiesthe Health Professionals Follow-up Study and the Nurses' Health Study. The researchers followed 46,237 men from June 1986 to June 2008 in the Health Professionals Follow-up Study, and 107,339 women from June 1984 to June 2008 in the Nurses' Health Study. The researchers identified 36,102 new cases of non-melanoma skin cancer and 29,447 new cases of other primary cancers.

A history of non-melanoma skin cancer was significantly associated with a 15 percent higher risk of other primary cancers in men, and a 26 percent higher risk of other primary cancers in women. When melanoma was excluded from this analysis, the rates changed slightly, with a history of non-melanoma skin cancer associated with an 11 percent higher risk of other primary cancers in men, and a 20 percent higher risk of other primary cancers in women.

After using statistical models to correct for multiple comparisons, looking at individual cancer sites, the researchers found that a history of non-melanoma skin cancer was significantly linked to an increased risk of breast and lung cancer in women, and an increased risk of melanoma in both men and women.

According to the researchers, these findings should be interpreted cautiously.

"Because our study was observational, these results should be interpreted cautiously and are insufficient evidence to alter current clinical recommendations," said Jiali Han, PhD, Channing Division of Network Medicine, BWH Department of Medicine and BWH Department of Dermatology. "Nevertheless, these data support a need for continued investigation of the potential mechanisms underlying this relationship."


'/>"/>

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital
Source:Eurekalert

Related medicine news :

1. Researchers identify new pathway, enhancing tamoxifen to tame aggressive breast cancer
2. Deficiency in p53 anti-tumor protein delays DNA repair after radiation, Moffitt researchers say
3. Wayne State researchers seek calcium channels to target cancer tumors
4. 3 Mass. General researchers among recipients of Clinical Research Achievement awards
5. Researchers identify and block protein that interferes with appetite-suppressing hormone
6. Resistance is futile: Researchers identify gene that mediates cisplatin resistance in ovarian cancer
7. Stanford researchers turn skin cells directly into the cells that insulate neurons
8. NYU researchers offer 12 principles for effective contraceptive counseling
9. Most effective PTSD therapies are not being widely used, researchers find
10. Gabriel Hortobagyi honored for mentoring minority researchers
11. Researchers develop tool to assist areas of infectious disease outbreaks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... March 24, 2017 , ... ... for its innovative EcoQube Frame vertical micro-veggies garden on Kickstarter . Surpassing ... the product – with nearly 2,000 consumers (and counting) already backing the campaign. ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... that they are now offering treatments for sleep apnea and TMJ at their ... Sleep apnea , specifically the obstructive type, is increasingly being treated at ...
(Date:3/24/2017)... ... March 24, 2017 , ... The law firm of ... is pleased to announce Westchester resident Lauren C. Enea has joined the firm as ... firm, will concentrate her practice in elder law, Medicaid planning and applications, and Wills, ...
(Date:3/24/2017)... ... March 24, 2017 , ... Gastro Health ... partnership to prep patients for colonoscopy at the HyGIeaCare® Center that is to ... Miami, FL. , The HyGIeaCare® Prep, cleared by the U.S. Food ...
(Date:3/24/2017)... , ... March 24, 2017 , ... ... first Certified Medical Reiki™ Master in Frederick, MD. Judy says, “I am passionate ... during what is often a very difficult and challenging time.” , A Certified ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... 24, 2017  Zymo Research Corp., also ... Robotics, Inc., who designs, manufactures and distributes ... that teams Zymo Research,s DNA methylation detection ... extraction products with Hamilton,s high-throughput automation platforms. ... for microbiomics and RNA isolation for use ...
(Date:3/24/2017)... Research and Markets has announced the addition of the "Dental Implants ... ... for Dental Implants in US$ Million. The report provides separate comprehensive analytics ... , Europe , Asia-Pacific , ... Annual estimates and forecasts are provided for the period 2015 through 2022. ...
(Date:3/24/2017)... -- FinancialBuzz.com News Commentary  ... According to new data published ... the legal cannabis market is projected to continue to grow ... from the current presidential administration. The report created by Arcview,s ... of growth in this industry are the passage and subsequent ...
Breaking Medicine Technology: