Navigation Links
Researchers observe an increased risk of cancer in people with history of non-melanoma skin cancer

Boston, MA A prospective study by researchers at Brigham and Women's Hospital (BWH) observed an association between risk of second primary cancer and history of non-melanoma skin cancer in white men and women.

The researchers found that people with a history of non-melanoma skin cancer had a modestly increased risk of getting cancer in the future, specifically breast and lung cancer in women and melanoma in both men and women. Non-melanoma skin cancer, which includes basal cell and squamous cell carcinoma, is the most common form of cancer in the United States.

The study will be published on April 23, 2013 in PLOS Medicine.

The researchers analyzed data from two large United States cohort studiesthe Health Professionals Follow-up Study and the Nurses' Health Study. The researchers followed 46,237 men from June 1986 to June 2008 in the Health Professionals Follow-up Study, and 107,339 women from June 1984 to June 2008 in the Nurses' Health Study. The researchers identified 36,102 new cases of non-melanoma skin cancer and 29,447 new cases of other primary cancers.

A history of non-melanoma skin cancer was significantly associated with a 15 percent higher risk of other primary cancers in men, and a 26 percent higher risk of other primary cancers in women. When melanoma was excluded from this analysis, the rates changed slightly, with a history of non-melanoma skin cancer associated with an 11 percent higher risk of other primary cancers in men, and a 20 percent higher risk of other primary cancers in women.

After using statistical models to correct for multiple comparisons, looking at individual cancer sites, the researchers found that a history of non-melanoma skin cancer was significantly linked to an increased risk of breast and lung cancer in women, and an increased risk of melanoma in both men and women.

According to the researchers, these findings should be interpreted cautiously.

"Because our study was observational, these results should be interpreted cautiously and are insufficient evidence to alter current clinical recommendations," said Jiali Han, PhD, Channing Division of Network Medicine, BWH Department of Medicine and BWH Department of Dermatology. "Nevertheless, these data support a need for continued investigation of the potential mechanisms underlying this relationship."


Contact: Marjorie Montemayor-Quellenberg
Brigham and Women's Hospital

Related medicine news :

1. Researchers identify new pathway, enhancing tamoxifen to tame aggressive breast cancer
2. Deficiency in p53 anti-tumor protein delays DNA repair after radiation, Moffitt researchers say
3. Wayne State researchers seek calcium channels to target cancer tumors
4. 3 Mass. General researchers among recipients of Clinical Research Achievement awards
5. Researchers identify and block protein that interferes with appetite-suppressing hormone
6. Resistance is futile: Researchers identify gene that mediates cisplatin resistance in ovarian cancer
7. Stanford researchers turn skin cells directly into the cells that insulate neurons
8. NYU researchers offer 12 principles for effective contraceptive counseling
9. Most effective PTSD therapies are not being widely used, researchers find
10. Gabriel Hortobagyi honored for mentoring minority researchers
11. Researchers develop tool to assist areas of infectious disease outbreaks
Post Your Comments:
(Date:10/13/2017)... ... ... While it’s often important to take certain medications during the night, finding them ... a solution. , She developed a prototype for MOTION LIGHT-UP PILL BOX to provide ... need to turn on a light when taking medication during the night, allowing the ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... PurhealthRX ... CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will ... and providing a CBD form that can be easily incorporated into liquid products, while ...
(Date:10/13/2017)... ... 13, 2017 , ... Apple Rehab Shelton Lakes , which specializes in ... the facility as part of a disaster drill on October 3rd. , Apple Rehab ... City Emergency Manager, as well as the Connecticut Long Term Care Mutual Aid ...
(Date:10/13/2017)... New York, NY (PRWEB) , ... October 13, 2017 , ... ... most influential people in business to advocate for action towards gender equality at their ... 18,000 views from around the globe, and reached a social audience of over 3 ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... giving viewers the lowdown on sciatica in a new episode of "Success Files," ... on current events and innovation and investigates each subject in-depth with passion and ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical ... innovative solutions for injectable drug administration, today shared the ... ID Adapter for improving the intradermal administration of polio ... Skin Vaccination Summit in May 2017 by Dr. ... Polio Department, World Health Organization (WHO), and recently published ...
(Date:10/4/2017)... 2017 OBP Medical , a ... devices, today announced regulatory approval from ... Agência Nacional de Vigilância Sanitária (ANVISA)) to market ... retractor with integrated LED light source and smoke ... exposure of a tissue pocket or cavity during ...
(Date:10/2/2017)... 2017 The Rebound mobile app is poised to ... the tide of prescription drug addiction. The app empowers users ... and stepping down their dosage in a safe, controlled manner ... 2017; the first 100,000 people to sign up will enjoy ... ...
Breaking Medicine Technology: