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Researchers map genomic differences in yellow fever, malaria mosquitoes
Date:6/17/2014

iseases. Understanding the mechanisms of the sex chromosomes may help to manipulate the sex ratio in mosquitoes and reduce disease transmission.

"The development of novel approaches to disease control will be definitely more successful if we better understand the differences and similarities in the genomes of the yellow fever and malaria vectors," Sharakhova said.

Although the genome of the yellow fever mosquito was published in 2007, the lack of a detailed physical genome map prevented researchers from analyzing the chromosome genetic composition and evolution. The large size of the yellow fever mosquito's genome about one third of the human genome size and five times larger than the malaria mosquito's genome complicated genomic mapping efforts.

"The physical genome map developed in this study will guide efforts to significantly improve the genome assembly for the yellow fever mosquito and will facilitate more advanced studies of the genome organization and chromosome evolution in mosquitoes," said Igor Sharakhov, an associate professor of entomology in the College of Agriculture and Life Sciences, a Fralin Life Science Institute affiliate, and co-author on the paper.


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Contact: Lindsay Taylor Key
ltkey@vt.edu
540-231-6594
Virginia Tech
Source:Eurekalert

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