Navigation Links
Researchers issue state-of-the-state on genetic-based testing and treatment for breast cancer
Date:3/25/2014

(Lebanon, NH, 03/24/2014)- Dartmouth researchers at its Norris Cotton Cancer Center have compiled a review of the role that information gathered through genetic testing plays in the diagnosis and treatment of breast cancer. The paper entitled "Personalized Therapy for Breast Cancer" was accepted on March 17, 2014, for publication in Clinical Genetics. The paper discusses targeted therapies, new biomarkers, and the quality of commercially available testing methods.

Genomic testing is changing the way breast cancer is diagnosed and treated. By examining a woman's genes to look for specific mutations or biomarkers, treatment can be personalized to the tumor cell's biology and a woman's genetics.

"A personalized approach increases the precision and success of breast cancer treatment," said Gregory Tsongalis, PhD, director of Molecular Pathology at Norris Cotton Cancer Center and lead author of the paper. "Molecular profiling exposes a tumor's Achilles' heel. We can see what messages the tumor cells are receiving and sending. It is a biological intelligence gathering mission in an attempt to interrupt the disease.

According to Tsongalis large scale genetic testing of breast cancer is not yet part of routine clinical care as it is with lung and colon cancers, even though he and his team run a genetics laboratory for routine cancer care. Genetic testing according to Tsongalis is a powerful weapon in the diagnosis and treatment of breast cancer.

With results from the genetic testing of a tumor cell's biology, clinicians categorize breast cancer in ways that allow them to select the most effective treatments. Based on genetic biomarkers, there are three categories of breast cancer:

  • ER-positive breast cancer needs hormones, such as estrogen to grow. Estrogen fuels cancer cell growth, stops cancer cells from dying, and helps the cells lay down roots to maintain blood supply for tumors. ER-positive cancers a
    '/>"/>

Contact: Donna Dubuc
donna.M.Dubuc@Dartmouth.edu
603-653-3615
The Geisel School of Medicine at Dartmouth
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers identify impaired new learning in persons with Parkinsons disease
2. Researchers identify potential new therapeutic target for controlling high blood sugar
3. Ottawa researchers find new pathway connected to type 2 diabetes
4. Shoulder revision repair surgery not as successful 2 years later, say researchers
5. Researchers find significant increase in painkillers prescribed to US adults in the ER
6. Dartmouth researchers develop new approach to chronic lymphocytic leukemia treatment
7. Researchers destroy cancer with cryoablation & nanoparticle-encapsulated anticancer drug
8. NYU researchers find majority of Latinas are unaware of their risk of diabetes
9. UF researchers find drug therapy that could eventually reverse memory decline in seniors
10. Researchers identify carbohydrates in a coal mine for cancer detection
11. Researchers X-ray living cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... September 15, 2014 Insurers across ... that bring providers on board as partners to ... When bundled payment programs are designed properly they ... incentivize hospitals to work collaboratively with providers, and ... On Sept. 24, the Atlantic Information Services webinar, ...
(Date:9/15/2014)... With a simple swab of the cheek, the ... to help personalize the treatment for patients with vascular disorders, ... approach to medicine is preventive care. But, it can be ... respond to specific drugs. A simple cheek swab test can ... physician to tailor medical therapy and optimize outcomes. , “By ...
(Date:9/15/2014)... 2014 AttorneyOne.com, a recognized authority on ... information from the FDA on sterile drug products ... FDA, the Agency announced on September 9, that it ... recall of all lots of its purportedly ... expired due to lack of sterility assurance. , In ...
(Date:9/15/2014)... Fancyflyingfox.com, the distinguished wedding dress manufacturer and ... beach wedding dresses . All clients can enjoy a ... up to 70 percent off. According to the company’s ... its loyal customers by launching the current sale. ... 300 different styles of special occasion gowns are provided. ...
(Date:9/14/2014)... 2014 Skin becomes dryer with age. Some ... and not moisturizing properly. However, there are inevitable internal factors ... for. , Two main reasons this occurs: , 1) Loss ... in the skin , During the aging process, skin produces ... responsible for important moisture retention and radiance of skin. ...
Breaking Medicine News(10 mins):Health News:Sept. 24 Webinar to Profile Geisinger Health System, BCBS of North Carolina’s Successful Bundled-Payment Programs 2Health News:Center for Vascular Medicine Offers Genetic Testing For Personalized Vascular Care 2Health News:FDA Requests Recall of Sterile Drug Products by Downing Labs (aka NuVision Pharmacy): AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Great Discounts On Beach Wedding Dresses Announced By Fancyflyingfox.com Now 2Health News:2 Reasons Skin Becomes Dryer with Age and What To Do About It, From Sublime Beauty® 2Health News:2 Reasons Skin Becomes Dryer with Age and What To Do About It, From Sublime Beauty® 3
... when added to existing meds, study finds , , ... helps relieve neuropathic pain in people with HIV, ... of Medicine study. , It included 28 HIV ... by opiates or other pain relievers. The researchers ...
... Increases 2008 Net Sales Projections; Affirms Top End of Adjusted* ... Earnings Guidance --, ... global specialty pharmaceutical and medication,delivery company, today reported results for the second quarter ... during the second quarter of 2008, compared to $869.3 ...
... Inclusion for Key, Emerging Biologic Agents That Will Launch ... Years, According to a ... 6 Decision Resources, one of the,world,s leading research ... 89 percent of surveyed rheumatologists,anticipate prescribing Roche/Chugai,s Actemra, following ...
... Aduromed Begins Next Step in Corporate Evolution, Restructuring the Company ... and Augmenting its Board and Management Team, ... Board: ADRM) a leading manufacturer of medical waste,treatment systems, today ... raise of $3.8 million of new equity capital. As,part of ...
... Software, Inc. today,announced the worldwide launch of iFastrack, ... software for reducing business,risk by tracking insurance certificates ... to manage their risk from,uninsured contractors, vendors or ... proof of insurance at the onset of a ...
... Increase Revenues by Up to $2 Million This ... Corporation (OTC,Bulletin Board: BDRR), a medical imaging and ... Imaging, Inc. has entered into,a joint venture (JV) ... Basic Solutions, Inc. will offer mobile cardiac stress ...
Cached Medicine News:Health News:Medicinal Marijuana Eases Neuropathic Pain in HIV 2Health News:Hospira Reports Second-Quarter 2008 Results 2Health News:Hospira Reports Second-Quarter 2008 Results 3Health News:Hospira Reports Second-Quarter 2008 Results 4Health News:Hospira Reports Second-Quarter 2008 Results 5Health News:Hospira Reports Second-Quarter 2008 Results 6Health News:Hospira Reports Second-Quarter 2008 Results 7Health News:Hospira Reports Second-Quarter 2008 Results 8Health News:Hospira Reports Second-Quarter 2008 Results 9Health News:Hospira Reports Second-Quarter 2008 Results 10Health News:Hospira Reports Second-Quarter 2008 Results 11Health News:Hospira Reports Second-Quarter 2008 Results 12Health News:Hospira Reports Second-Quarter 2008 Results 13Health News:Hospira Reports Second-Quarter 2008 Results 14Health News:Hospira Reports Second-Quarter 2008 Results 15Health News:Hospira Reports Second-Quarter 2008 Results 16Health News:Hospira Reports Second-Quarter 2008 Results 17Health News:Hospira Reports Second-Quarter 2008 Results 18Health News:Hospira Reports Second-Quarter 2008 Results 19Health News:Hospira Reports Second-Quarter 2008 Results 20Health News:Hospira Reports Second-Quarter 2008 Results 21Health News:Hospira Reports Second-Quarter 2008 Results 22Health News:Hospira Reports Second-Quarter 2008 Results 23Health News:Hospira Reports Second-Quarter 2008 Results 24Health News:Hospira Reports Second-Quarter 2008 Results 25Health News:Hospira Reports Second-Quarter 2008 Results 26Health News:Hospira Reports Second-Quarter 2008 Results 27Health News:Hospira Reports Second-Quarter 2008 Results 28Health News:Eighty-Nine Percent of Surveyed Rheumatologists Say They Will Prescribe Roche/Chugai's Actemra for Rheumatoid Arthritis 2Health News:Eighty-Nine Percent of Surveyed Rheumatologists Say They Will Prescribe Roche/Chugai's Actemra for Rheumatoid Arthritis 3Health News:Aduromed Closes Restructuring and Raises $3.8 Million of New Equity Capital 2Health News:Aduromed Closes Restructuring and Raises $3.8 Million of New Equity Capital 3Health News:GG-One Software Announces iFastrack to Help Avoid Insurance Disasters 2Health News:Bederra Corp.'s Lumar Imaging Division Enters Into Joint Venture With Basic Solutions 2
(Date:9/15/2014)... LONDON , BERLIN and ... The global market has the potential to grow to ... leading provider of market research reports has announced pharma industry ... Esophageal Cancers to 2019 - Crowded Late-Stage Pipelines and Favorable ... in terms of US pricing structures and the anticipated approval ...
(Date:9/15/2014)... GENEVE , September 15, 2014 /PRNewswire/ ... des principaux fabricants européens de sortir ou ... marché ou au soutien réglementaire de la ... alcaloïdes tropaniques comme principes pharmaceutiques actifs (API), ... la nortropine, le méthylbromure d,homatropine, le bromhydrate d,homatropine, ...
(Date:9/14/2014)... DIEGO , Sept. 14, 2014 HUYA ... global development of China,s pharmaceutical ... Institute of Pharmaceutical Research (TIPR) to develop medical ... and the western world, for global markets. ... venture, to be known as TIPR-HUYA Advancing Innovative Medicines ...
Breaking Medicine Technology:Monoclonal Antibodies Market for Gastric and Esophageal Cancers to Double by 2019 2Monoclonal Antibodies Market for Gastric and Esophageal Cancers to Double by 2019 3Alchem International s'engage à poursuivre et étendre la production des principes pharmaceutiques actifs contenant des alcaloïdes tropaniques et à soutenir la réglementation pour combler l'écart d'approvisionnement 2Alchem International s'engage à poursuivre et étendre la production des principes pharmaceutiques actifs contenant des alcaloïdes tropaniques et à soutenir la réglementation pour combler l'écart d'approvisionnement 3HUYA Bioscience International and TIPR Announce Joint Venture to Develop Medical Innovation for Global Markets 2HUYA Bioscience International and TIPR Announce Joint Venture to Develop Medical Innovation for Global Markets 3HUYA Bioscience International and TIPR Announce Joint Venture to Develop Medical Innovation for Global Markets 4
... (Nasdaq: ARAY ), the premier radiation ... Especialidad in Monterrey, Mexico has starting treating patients with ... is the first center in Mexico now offering patients ... anywhere in the body. The CyberKnife System ...
... Jan. 17, 2012  Ventana Medical Systems, Inc. (Ventana), ... that it has entered into a strategic collaboration ... a molecular companion diagnostic test intended to identify ... Bayer antibody-drug conjugate (ADC). Ventana,s diagnostic immunohistochemistry platform ...
Cached Medicine Technology:First CyberKnife Robotic Radiosurgery System Goes Live in Mexico 2First CyberKnife Robotic Radiosurgery System Goes Live in Mexico 3First CyberKnife Robotic Radiosurgery System Goes Live in Mexico 4Ventana Medical Systems, Inc. to Collaborate with Bayer on Companion Diagnostic Test for New Biological Cancer Therapy 2Ventana Medical Systems, Inc. to Collaborate with Bayer on Companion Diagnostic Test for New Biological Cancer Therapy 3
The ImagingPlanet 55 mm Surgical Microscope Adapter. Superior optical quality and precise engineering make this 55mm focal length adapter an excellent decision for use with your Zeiss surgical micro...
The ImagingPlanet 70 mm Surgical Microscope Adapter. Superior optical quality and precise engineering make this 70 mm focal length adapter an excellent decision for use with your Leica surgical micr...
... Manage and Retrieve a ... DVMR- office, the first digital ... the physician's office environment. DVMR ... of high-resolution cameras for simple ...
Research Grade Microscope Camera from ImagingPlanet Research Microscopy Group, a superior imaging technology that delivers increased image resolution and precise color accuracy at an affordable pric...
Medicine Products: