Navigation Links
Researchers inject nanofiber spheres carrying cells into wounds to grow tissue
Date:4/17/2011

ANN ARBOR, Mich.---For the first time, scientists have made star-shaped, biodegradable polymers that can self-assemble into hollow, nanofiber spheres, and when the spheres are injected with cells into wounds, these spheres biodegrade, but the cells live on to form new tissue.

Developing this nanofiber sphere as a cell carrier that simulates the natural growing environment of the cell is a very significant advance in tissue repair, says Peter Ma, professor at the University of Michigan School of Dentistry and lead author of a paper about the research scheduled for advanced online publication in Nature Materials. Co-authors are Xiaohua Liu and Xiaobing Jin.

Repairing tissue is very difficult and success is extremely limited by a shortage of donor tissue, says Ma, who also has an appointment at the U-M College of Engineering. The procedure gives hope to people with certain types of cartilage injuries for which there aren't good treatments now. It also provides a better alternative to ACI, which is a clinical method of treating cartilage injuries where the patient's own cells are directly injected into the patient's body. The quality of the tissue repair by the ACI technique isn't good because the cells are injected loosely and are not supported by a carrier that simulates the natural environment for the cells, Ma says.

To repair complex or oddly shaped tissue defects, an injectable cell carrier is desirable to achieve accurate fit and to minimize surgery, he says. Ma's lab has been working on a biomimetic strategy to design a cell matrix---a system that copies biology and supports the cells as they grow and form tissue---using biodegradable nanofibers.

Ma says the nanofibrous hollow microspheres are highly porous, which allows nutrients to enter easily, and they mimic the functions of cellular matrix in the body. Additionally, the nanofibers in these hollow microspheres do not generate much degradation byproducts that
'/>"/>

Contact: Laura Bailey
baileylm@umich.edu
734-764-1552
University of Michigan
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Wistar researchers follow a path to a potential therapy for NF2, a rare tumor disorder
2. Whales Not Just Singing the Same Old Song, Researchers Say
3. Boston University researchers find most substance-dependent individuals report poor oral health
4. University of Granada researchers make the first bioartificial organ in Spain
5. Queens researchers pioneer needle-free test for premature babies
6. Mechanism for invasion of tumorous cells discovered by Hebrew University researchers
7. Researchers find anatomic differences after robotic-assisted radical prostatectomy
8. Researchers present new findings on cancer and gene therapy
9. Fox Chase researchers find that fish oil boosts responses to breast cancer drug tamoxifen
10. Fox Chase researchers report that naproxen reduces tumors in a mouse model of colon cancer
11. UPCI, Pitt researchers present findings of cancer studies at AACR 102nd Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/3/2014)... CS3 Technology, a Sage North America ... of Sage 100 ERP, Sage 500 ERP, and Sage ... Dollar Club achiever for surpassing a million dollars in ... Technology and all Million Dollar Club achievers for the ... its business partners and the mutual customers they serve. ...
(Date:9/3/2014)... Job seekers who are interested in expanding their ... do both on iHire. By incorporating MOOCtracks into the ... investigating employment and educational opportunities in the same place. ... skills gaps and challenging the landscape of education by ... and mortar universities. To make it easier for their ...
(Date:9/2/2014)... (PRWEB) September 03, 2014 IMCA Speedway ... kick off on September 1, 2014 at the IMCA ... the pre-race ceremony will include a check presentation to ... The Warriors® is a national nonprofit organization that assists ... fallen who have sustained physical and psychological wounds in ...
(Date:9/2/2014)... 2014 Scientists, physicians, patients, families, ... Bay from September 4-6 for the Friedreich’s Ataxia ... FARA Energy Ball Gala. The Energy Ball ... in their pursuit of treatment and cure for ... neuromuscular disease Friedreich’s ataxia (FA). , “The annual ...
(Date:9/2/2014)... Illinois (PRWEB) September 02, 2014 ... Chief Executive Officer and Chief Information Officer Strategy ... Carlton Chicago. , Becker's Hospital Review Chief Executive ... together hospital and health system Chief Executive Officers, ... hospital and health system executives through high-quality ...
Breaking Medicine News(10 mins):Health News:CS3 Technology Named a Sage Million Dollar Club Achiever for 2013-2014 2Health News:iHire Announces Partnership with MOOCtracks 2Health News:IMCA to Present Donation to Hope For The Warriors 2Health News:Event Gathers World-Renowned Researchers and Community Leaders to Find a Cure for Rare Disease, Friedreich’s Ataxia 2Health News:Event Gathers World-Renowned Researchers and Community Leaders to Find a Cure for Rare Disease, Friedreich’s Ataxia 3Health News:Becker's Healthcare Announces Hospital CEO and CIO Strategy Roundtables 2Health News:Becker's Healthcare Announces Hospital CEO and CIO Strategy Roundtables 3Health News:Becker's Healthcare Announces Hospital CEO and CIO Strategy Roundtables 4
... during Long-Term Care Awareness Week, WASHINGTON, Nov. ... they have coverage for long-term care expenses,according to ... Insurance,Plans (AHIP). The survey found that many Baby ... services and have not thought about,long-term care insurance. ...
... -- Recovery from heart attacks is best served by ... of patients who have had a heart attack stop ... results from a Mayo Clinic study presented today at ... Fla. , The Mayo data also show that in ...
... such fare more likely to act out at 7, 10, ... boys exposed to violent television -- even cartoons -- are ... , Their findings don,t definitively prove that TV makes children ... according to the researchers. But the link does appear solid ...
... single author. With research being conducted by teams of scientists, ... to a new study led by a scientist at the ... from evenly distributed, and the order in which the authors ... findings appear in the Nov. 1 issue of the scientific ...
... Prescribe Exercise to Patients, WASHINGTON, Nov. 5 ... the American Medical Association (AMA) today,launched Exercise is ... to incorporate physical activity and exercise into their,daily ... prescribe,exercise to their patients., A recent survey ...
... Therapeutics, Inc.,(Nasdaq: CVTX ) announced today that ... the primary composite endpoint of CV,death, myocardial infarction ... in 1,935 patients with an elevated (>80pg/ml) level ... study (p=0.009). The data were presented today ...
Cached Medicine News:Health News:New Survey Finds One in Four Baby Boomers Erroneously Believe They Have Coverage for Long-Term Care Expenses 2Health News:New Survey Finds One in Four Baby Boomers Erroneously Believe They Have Coverage for Long-Term Care Expenses 3Health News:Mayo Clinic study finds that after heart attack most patients stop taking life-saving drugs 2Health News:TV Violence May Spur Aggression in Boys 2Health News:TV Violence May Spur Aggression in Boys 3Health News:Lost in the middle: author order matters, new paper says 2Health News:ACSM and AMA Launch 'Exercise Is Medicine' Program 2Health News:ACSM and AMA Launch 'Exercise Is Medicine' Program 3Health News:Ranexa(R) Significantly Reduces Incidence of CV Death, MI or Recurrent Ischemia in MERLIN TIMI-36 Patients With Elevated BNP 2Health News:Ranexa(R) Significantly Reduces Incidence of CV Death, MI or Recurrent Ischemia in MERLIN TIMI-36 Patients With Elevated BNP 3
(Date:9/2/2014)... ALBANY, New York , September 2, 2014 ... market report published by Transparency Market Research "Latin ... and Monitoring Devices, Therapeutic Home Healthcare Devices, Mobility ... Telehealth and Telemedicine, Respiratory Therapy, Infusion Therapy and ... Share, Growth, Trends and Forecast, 2014 - 2020" ...
(Date:9/2/2014)... 2, 2014 According to the ... Pre-packed, Analytical, Preparative), by Material (Metal, Glass, Plastic), by ... Forecast to 2018", published by MarketsandMarkets, the Chiral Chromatography ... is poised to grow at a CAGR of 5.2% ... Browse 90 market data tables and 15 ...
(Date:9/2/2014)... 2, 2014  Avanir Pharmaceuticals, Inc. (NASDAQ: AVNR ... of the company at the Morgan Stanley Global Healthcare Conference ... Presentation date: Tuesday September 9, 2014 , Presentation time: ... and 30-day archive of this presentation will be available at ... Avanir Pharmaceuticals, Inc. is a biopharmaceutical company focused ...
Breaking Medicine Technology:Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 2Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 3Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 4Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 5Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 6Chiral Chromatography Column Market Worth $87.8 Million by 2018 2Chiral Chromatography Column Market Worth $87.8 Million by 2018 3Chiral Chromatography Column Market Worth $87.8 Million by 2018 4
... WASHINGTON, Nov. 16, 2011 The proliferation of brand ... generics to more expensive brands, will increase costs by ... employers, unions, and state employee plans, according to new ... Care Management Association (PCMA).  The use of these ...
... Inc. (NYSE Amex: PIP ) announced today that ... bioscavenger programs will be presented at the 2011 Chemical and ... in Las Vegas, NV, November 14-18, 2011. "The ... industry meetings and it is an honor to present among ...
Cached Medicine Technology:Brand Drug 'Copay Coupons' Undermine Generics, Raise Health Costs by $1.1 Billion in Michigan 2PharmAthene to Present at the 2011 Chemical and Biological Defense Science and Technology Conference 2PharmAthene to Present at the 2011 Chemical and Biological Defense Science and Technology Conference 3
The CGPL capsulotomy contact glass was designed by Riquin, Fankhauser et al. for the dissection of opacified posterior lens capsules and membranes in the pupillary and retropupillary space with the Y...
The CGIL iridectomy contact glass was designed by Riquin, Fankhauser et al. to perform full thickness peripheral laser iridectomies....
The Retina 145 L direct contact glass is a panfundus wide-angle viewing device designed to facilitate the problem-free diagnosis and treatment of the retina as far as the equator....
The CGRL is a Wide Angle Contact Glass designed for laser photocoagulation and diagnosis of the retina....
Medicine Products: