Navigation Links
Researchers important markers of high risk of type 2 diabetes
Date:4/25/2008

Doctors are aware of a range of risk factors, mostly related to the patients family history, overweight, and lifestyle, that contribute to the risk of developing type 2 diabetes. Now researchers at the University of Warwick have found markers that indicate endothelial dysfunction (changes in the cells which line the blood vessels) and sub-clinical systemic inflammation can also help identify a far greater number of people at high risk for future development of type 2 diabetes.

In a study led by Dr Saverio Stranges, Associate Professor of Cardiovascular Epidemiology at Warwick Medical School at the University of Warwick, the team looked at a protein called E-selectin, whose presence is an indication of endothelial dysfunction, white blood cell count and levels of albumin, which are marker for sub-clinical systemic inflammation.

They found high levels of E-selectin and white blood cell count with low levels of serum albumin were clear predictors of high risk for type 2 diabetes. The researchers found that traditional risk factors such as obesity or family history helped identify 65% of all patients who were at high risk of developing type 2diabetes. But when the information from these three markers was added this increased from 65% to 73% which means doctors could be able to spot a greater number of people at risk of type 2 diabetes at an early stage.

The research used data taken from the Western New York Health Study. This was a six-year longitudinal study of diabetes and cardiovascular risk factors among residents of Erie and Niagara Counties, New York.

Dr Stranges said: "High levels of E-selectin and white blood cells with low levels of serum albumin can indicate endothelial dysfunction and sub-clinical systemic inflammation. These findings corroborate the notion that both these conditions play an important role in the development of the disease. Endothelial dysfunction is also regarded as a key event in the development and progression of atherosclerosis. Finding new markers for type 2 diabetes will help us gain a greater understanding of the condition and possibly open up new possibilities for the way we prevent and treat it."


'/>"/>

Contact: Peter Dunn
p.j.dunn@warwick.ac.uk
44-077-676-55860
University of Warwick
Source:Eurekalert

Related medicine news :

1. Cancer researchers receive NIH grant to advance brain tumor therapies from lab to clinical trials
2. Researchers Identify Contaminant in Tainted Heparin
3. UMass Medical School researchers awarded pediatric HIV vaccine development grant
4. Researchers identify new cell targets for preventing growth of breast and other tumors
5. Melanoma lurks in larger skin lesions, NYU researchers find
6. Reduced Funds for Cancer is Cost of Iraq, Say Ex-White House Aide, Cancer Researchers
7. MU researchers reveal communication tactics used by sexual predators to entrap children
8. Penn researchers find potential in yeast for selecting Lou Gehrigs disease drugs
9. MU researchers find clue to cataract formation
10. Researchers evaluating food allergy treatment
11. U of M researchers identify process that may help treat Parkinsons, spinal cord injuries
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... Livermore, California (PRWEB) , ... December 02, 2016 ... ... business professionals, proudly announces the launch of its 60-day free trial program for ... round trip shipping make the offer a truly hassle free experience. , FlexiSpot’s ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... With the ... through rehabilitation of an injury, patients must find the one that works for them. ... pain, he created a machine that worked and decided to share it with others. ...
(Date:12/2/2016)... ... 02, 2016 , ... Mediaplanet is proud to announce the ... the innovative treatments, therapeutic technologies, and revolutionized nutrition that are helping patients and ... 6 years in the last 3 decades,” says Dr. Valentine Fuster, a world-renowned ...
(Date:12/2/2016)... ... December 02, 2016 , ... Sourced from the Isbre Springs ... properties including its unmatched natural purity of just 6 ppm TDS (Total Dissolved Solids) ... Nothing Water has been available in several ShopRite and FoodTown stores in NJ and ...
(Date:12/2/2016)... , ... December 02, 2016 , ... ... announced today that it has raised $6.0 million in an initial round of ... Health’s conviction that patients and their caregivers can receive far better care through ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... Research and Markets has announced the addition of the "Global ... report to their offering. ... , The global ultrasound device market ... to grow at a CAGR of 5.5% during 2016-2022. Based on portability, ... forecast period, a CAGR of 8.8% in the global market. Among the ...
(Date:12/2/2016)... ATLANTA , Dec. 2, 2016 Quantum ... screening and expert radiologist interpretation directly to women at ... partners with corporations, such as Delta Air Lines and ... cancer screening as a component of wellness initiatives. ... women of SunTrust. It enables them to have a ...
(Date:12/2/2016)... 2016 In the first ever attempt to ... derived from C. sativa, the Hebrew University in Jerusalem, ... Federico II , the Universita` del Piemonte Orientale and ... integrated and unified inventory of phytocannabinoids of different botanical ... the remarkable chemical and structural diversity of phytocannabinoids. As ...
Breaking Medicine Technology: