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Researchers identify potential target to delay metastatic pancreatic cancer and prolong survival
Date:12/21/2011

al for cancer progression, a mechanism that can be exploited, the researchers point out.

This is another example of how researchers from the Center are bridging basic scientific discoveries with physicians' needs for their patientsby discovering and improving upon new targeted therapies for pancreatic cancer that may eventually be tested in clinical trials.

"Our survival results are very exciting because a drug, known as ADH-1, that specifically targets N-cadherin is already in clinical trial for melanoma" Dr. Radice said. "The next step is to test this N-cadherin-function blocking drug or a similar compound in the pancreatic cancer mouse model to see if it can prolong survival."


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Contact: Steve Graff
stephen.graff@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

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