Navigation Links
Researchers identify potential new therapeutic target for controlling high blood sugar
Date:3/19/2014

els of two enzymes in the liver, diacylglycerol kinase and phospholipase D. Researchers also discovered a marked increase in glucose production in the livers of the lipodystrophic mice.

The lack of normal insulin signaling in these lipodystrophic mice led to unrestricted production of phosphatidic acid, Dr. Agarwal explained, contributing to development of hyperglycemia, or high blood sugar.

Besides revealing a new potential therapy to test for treatment of diabetes, the studys findings may have implications in understanding how cancer develops. Increased phosphatidic acid levels may play an important role in a metabolic pathway that supplies energy to cancer cells.

Lead author Dr. Shireesha Sankella, a postdoctoral researcher in the Division of Nutrition and Metabolic Diseases, now plans to test the inhibitors of diaclyglycerol kinase and phospholipase D in cultured cells and in animals to understand the molecular mechanisms for increased glucose production by phosphatidic acids in liver and cancer cells.


'/>"/>
Contact: Debbie Bolles
debbie.bolles@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Ottawa researchers find new pathway connected to type 2 diabetes
2. Shoulder revision repair surgery not as successful 2 years later, say researchers
3. Researchers find significant increase in painkillers prescribed to US adults in the ER
4. Dartmouth researchers develop new approach to chronic lymphocytic leukemia treatment
5. Researchers destroy cancer with cryoablation & nanoparticle-encapsulated anticancer drug
6. NYU researchers find majority of Latinas are unaware of their risk of diabetes
7. UF researchers find drug therapy that could eventually reverse memory decline in seniors
8. Researchers identify carbohydrates in a coal mine for cancer detection
9. Researchers X-ray living cancer cells
10. Fox Chase researchers discover new mechanism of gene regulation
11. Penn researchers show nuclear stiffness keeps stem cells and cancer cells in place
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers identify potential new therapeutic target for controlling high blood sugar
(Date:5/4/2015)... York, NY (PRWEB) May 04, 2015 ... specialized insurance programs, announces the expansion of coverage for ... is a leading provider of industry-tailored insurance and proactive ... McNeil & Company, we are dedicated to providing our ... to meet their many evolving needs. We are excited ...
(Date:5/4/2015)... Healthcare Solutions is proud to be a sponsor at ... in Baltimore, MD from May 11 – 13, 2015. ... opportunity for clients to gather to network, attend educational ... to sponsoring the event, TROY Healthcare Solutions will be ... can stop by the TROY booth and see sample ...
(Date:5/4/2015)... 2015 Baptist Medical Center Jacksonville ... Get With The Guidelines®-Stroke Gold Plus Quality Achievement ... The award recognizes the hospital’s commitment and success ... appropriate treatment according to nationally recognized, research-based guidelines ... receive the Gold Plus Quality Achievement Award, hospitals ...
(Date:5/4/2015)... Now in its seventh year, the IPC ... made outstanding contributions to the company, to their facilities ... and post-acute care settings. The five award categories are: ... Year, Advanced Practice Clinician of the Year, Newcomer Provider ... Recipients are selected by IPC’s senior management team. , ...
(Date:5/4/2015)... Los Angeles, CA (PRWEB) May 04, 2015 ... Kevin Sands, is now offering a more comfortable and ... been the restoration of choice for those who have ... patients. Dentures can feel insecure or slip at the ... the patient eats or talks. They can also painfully ...
Breaking Medicine News(10 mins):Health News:Insurance Leader McNeil & Company Expands Coverage for Emergency Services Insurance Program (ESIP), Launches Enhancements to Property and Casualty Insurance Package 2Health News:Insurance Leader McNeil & Company Expands Coverage for Emergency Services Insurance Program (ESIP), Launches Enhancements to Property and Casualty Insurance Package 3Health News:TROY Healthcare to Exhibit at the Cerner North Atlantic Regional User Group Conference 2Health News:TROY Healthcare to Exhibit at the Cerner North Atlantic Regional User Group Conference 3Health News:Baptist Medical Center Jacksonville Receives Top Honor for Stroke Care 2Health News:Baptist Medical Center Jacksonville Receives Top Honor for Stroke Care 3Health News:Baptist Medical Center Jacksonville Receives Top Honor for Stroke Care 4Health News:IPC Healthcare Announces Clinicians of the Year 2Health News:IPC Healthcare Announces Clinicians of the Year 3Health News:Los Angeles Dental Implants Doctor, Kevin Sands DDS, Now Offers a More Comfortable and Aesthetically-Pleasing Solution to Denture-Wearers 2
... (HealthDay News) -- A certain area of the cerebral cortex ... smoked, finds a new study. The cerebral cortex is ... in reward, impulse control and decision making. German researchers ... smokers and 21 people who never smoked. Using these images, ...
... work night and rotating shifts are almost twice as likely ... day shifts, according to a study by researchers at the ... current issue of the Scandinavian Journal of Work, Environment ... collected as part of Statistics Canada,s Survey of Labour and ...
... HealthDay Reporter , MONDAY, Nov. 1 (HealthDay News) -- There may ... exercise regularly seem to have fewer and milder colds, a new ... catch a cold two to four times a year, and children ... colds sap about $40 billion from the U.S. economy in direct ...
... cancer, one of the most prevalent cancers in women, ... about 40,000 deaths annually. The disease often extends to ... process in which cancer cells invade blood vessels or ... prognosis for patients. Some scientists argue that evidence ...
... Nov. 2 (HealthDay News) -- Extroverts are more vulnerable to ... social activity than after they,ve been alone, researchers have found. ... and 25 introverts (reserved, shy types), aged 18 to 39, ... or a "socially impoverished group." Those in the socially ...
... New York, NY, November 2, 2010An initiative by the ... of proven value less expensive for their employees succeeded ... to a Commonwealth Fund-supported study published in this month,s ... by Niteesh K. Choudhry at Brigham and Women,s Hospital, ...
Cached Medicine News:Health News:Shift work linked to higher risk of work injury: UBC study 2Health News:Exercise May Help Beat the Common Cold 2Health News:Exercise May Help Beat the Common Cold 3Health News:Fox Chase researchers identify risk factors for the spread of breast cancer to lymph nodes 2Health News:Socializing Tied to Sleep Deprivation in Extroverts 2Health News:Eliminating or reducing cost-sharing for high-value prescription drugs improves medication use 2
(Date:5/4/2015)... , May 4, 2015   The New ... injection, Kybella, from internationally acclaimed plastic surgeon, Dr. ... and Drug Administration, is proven to reduce fat deposits ... The active ingredient in Kybella, ... gives plastic surgeons the ability to reshape this area ...
(Date:5/4/2015)... N.J. , May 4, 2015 Thirty-six ... percent seek help. During May – National Hearing Month ... loss could be missing out on the sounds of ... the trees. To ensure that you won,t ... that color our world, Oticon, Inc. offers practical advice: ...
(Date:5/4/2015)... May 4, 2015 PAREXEL International Corporation (NASDAQ: ... the UBS Healthcare Conference on Monday, May 18, 2015, in ... and Chief Financial Officer will be making a presentation on ... A live webcast of the presentation will be available ... in the Upcoming Events portion of the main page, ...
Breaking Medicine Technology:Dr. Rod Rohrich Provides Medical Expertise on Kybella 2Dr. Rod Rohrich Provides Medical Expertise on Kybella 3It's Better Hearing Month 2PAREXEL International to Present at UBS Healthcare Conference 2
... Nov. 11 Shire plc ... biopharmaceutical company, today announced the re-launch of FOCUS ( ... patient support program for adults taking once-daily Vyvanse ... treatment of Attention-Deficit/Hyperactivity Disorder (ADHD), and the only online, branded ...
... Deloitte Recap LLC (Recap) has launched "Development ... Series by Deloitte. The series of biopharmaceutical business ... service tailored toward business development, corporate strategy, financial, ... , "Development Optimizer" provides flexible analytical tools for ...
Cached Medicine Technology:Shire Re-Launches FOCUS, an Online, Personalized Patient Support Program for Adults with ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII 2Shire Re-Launches FOCUS, an Online, Personalized Patient Support Program for Adults with ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII 3Shire Re-Launches FOCUS, an Online, Personalized Patient Support Program for Adults with ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII 4Shire Re-Launches FOCUS, an Online, Personalized Patient Support Program for Adults with ADHD Taking Vyvanse(R) (lisdexamfetamine dimesylate) Capsules CII 5Deloitte Recap Launches New Solution for Clinical Development 2Deloitte Recap Launches New Solution for Clinical Development 3
... Misys Laboratory is a ... that manages specimen data ... specimen tracking to final ... Laboratory is a multi-module ...
...
... IntelliLab is a full-featured ... the processing requirements,of clinical laboratories ... labs. IntelliLab provides order,management, barcode ... control and reporting tools to,ensure ...
... of a cuff for opening the drape ... the cassette. , ,Seamless side construction ... helping to prevent the cassette to be ... ,Adhesive closure provides a secure seal while ...
Medicine Products: