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Researchers identify mechanism that could help old muscle grow
Date:6/17/2014

ntion could help control healthcare costs. "Age-related muscle loss has been associated with a myriad of other health problems," said senior author Roger A. Fielding, Ph.D., director of the Nutrition, Exercise Physiology and Sarcopenia Laboratory at the USDA HNRCA at Tufts University. "Muscle mass is closely tied to our metabolism and losing it increases the risk of developing metabolic diseases like type 2 diabetes and cardiovascular disease. We also know that a program of moderate physical activity, including resistance exercises, can strongly influence a person's chances of maintaining their ability to walk after age 70."

In addition to resistance exercises, scientists are exploring different approaches to preserving and building muscle mass in older adults. "A few studies suggest gene therapy, nutrient supplementation or hormone replacement therapy can assist with building muscle," said Fielding, who is also a professor at the Friedman School of Nutrition Science and Policy at Tufts University and the Tufts University School of Medicine. "Our identification of a possible microRNA target could help advance the study of these largely untested, but promising approaches to promoting muscle growth in older people."

The authors note the small size of the study necessitates future research in clinical models and in men and women, particularly those who have sarcopenia.


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Contact: Andrea Grossman
617-636-3728
Tufts University, Health Sciences Campus
Source:Eurekalert

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