Navigation Links
Researchers identify mechanism that could help old muscle grow
Date:6/17/2014

[Boston, MA June 17, 2014]─ Sarcopenia the significant loss of muscle mass and function that can occur as we age is associated with many chronic conditions such as diabetes, high cholesterol and obesity. In findings published online ahead of publication in the September 2014 issue of the FASEB Journal, researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University identify a muscle-building mechanism that could be important in addressing sarcopenia.

When people strength train the body responds by making muscle. The researchers recruited 16 healthy but sedentary men to perform a single bout of resistance exercise to trigger muscle growth and examined tissue samples taken before and six hours after the exercise. Half of the men were in their twenties and the other half in their seventies.

"In order for the body to make proteins that build muscle, certain genes need to be turned on," said lead author Donato A. Rivas, Ph.D., a scientist in the Nutrition, Exercise Physiology and Sarcopenia Laboratory at the USDA HNRCA at Tufts University. "We noticed the older people had a lot fewer genes turned on compared to the younger people, showing us their muscles weren't responding as well to the exercise."

Rivas and colleagues observed that the level of microRNAs, small RNA molecules that have a prominent role in regulating genes, was lower in the muscle tissue of the older men, compared to younger men. "One of the steps in building muscle seems to be missing in the older men, preventing them from responding to the exercise as strongly as the younger men did," Rivas said. "It is possible that the suppression of these microRNAs is setting off a chain of events that is causing older people to be less efficient in developing muscle."

With the population of older adults in the United States projected to increase significantly in the coming decades, more effective sarcopenia treatment and preve
'/>"/>

Contact: Andrea Grossman
617-636-3728
Tufts University, Health Sciences Campus
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers identify new compound to treat depression
2. Researchers create better methods to detect E. coli
3. UGA researchers discover new method to reduce disease-causing inflammation
4. Ottawa researchers key to new neuromuscular disease care and research network
5. Researchers uncover new insights into developing rapid-acting antidepressant for treatment-resistant depression
6. Broad Institute, MGH researchers chart cellular complexity of brain tumors
7. Researchers uncover common heart drugs link to diabetes
8. Mayo Clinic researchers discover new form of cancer
9. Researchers recast addiction as a manageable disease
10. Mount Sinai researchers identify protein that keeps blood stem cells healthy as they age
11. Berkeley Lab researchers create nanoparticle thin films that self-assemble in 1 minute
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2015)... Mauritius is a seemingly idyllic and tranquil ... km (1,243 miles) off the southeastern coast of Africa, ... melting pot where everyone lives together in harmony. , ... is riddled with drug abuse. In fact, it carries ... of any nation in eastern Africa. , “Many youngsters, ...
(Date:4/20/2015)... April 20, 2015 “Consumers deserve to know ... washing their children’s hair will not put their health at ... of the National Alliance for Hispanic Health, the nation’s leading ... FDA has not had authority to ensure cosmetic and personal ... has FDA had authority to get products off the shelves ...
(Date:4/20/2015)... Advance Home Care Supply understands that ordering adult ... prefer not to share with others. As such, the company ... allowing customers to order the products and supplies they need ... a neighbor or passerby knowing what the customer has purchased. ... orders and no minimum order limit is required. Also, there ...
(Date:4/20/2015)... TROY Healthcare Solutions will be hosting ... software, which provides the ultimate level of security for ... the Anthem Suite Hotel in the Socrates Room, located ... , Beginning at 7 AM, TROY Healthcare Solutions will ... Healthcare Solutions will offer brief 15-20 minute presentations each ...
(Date:4/20/2015)... (PRWEB) April 20, 2015 Grateful Dead ... were united as one until 1995. The group was more ... blues, reggae, rock, bluegrass, folk, space rock, country, and other ... as the ultimate jam band. The group was inducted into ... in total has sold more than 35 million records worldwide. ...
Breaking Medicine News(10 mins):Health News:Voice For Humanity: Choolun Bhojoo leads the fight to rid Mauritius of a drug plague 2Health News:Statement of National Alliance for Hispanic Health on Senate Introduction of Personal Care Products Safety Act 2Health News:Advance Home Care Supply Proud to Offer Discreet Delivery For All Orders 2Health News:Advance Home Care Supply Proud to Offer Discreet Delivery For All Orders 3Health News:TROY Healthcare to Offer Prescription Solutions that Could Save a Health System $100,000 2Health News:TROY Healthcare to Offer Prescription Solutions that Could Save a Health System $100,000 3Health News:Grateful Dead Tickets at Levi’s Stadium in Santa Clara: Ticket Down Slashes Grateful Dead Tickets in Santa Clara @ Levi’s Stadium for "Fare Thee Well" 50th Anniversary 2
... , OAKLAND, Calif., Aug. 5 Anyone ... record in a standardized format understood at hospitals, clinics and ... specializing in chronic illness support, geriatric care management and private ... Your Own Health to re-brand and sell the popular ...
... , , PHOENIX, Aug. 5 ... hand must not become a vehicle for taking lives through abortion ... report at the organization,s 127th annual convention here today. Referring to ... declared that "Health care reform must be abortion-free." , , ...
... direction for diabetes treatment , WEDNESDAY, Aug. 5 (HealthDay News) ... role in the control of blood sugar production in the ... first time that CCK from the gut activates receptors to ... axis," Tony Lam of the University of Toronto said in ...
... , , , ... a privately-held specialty pharmaceutical company, today announced that it has ... IMS data indicates the combined U.S. market for these two ... and shipping both products immediately. , , ...
... an animal model that provides strong evidence why imatinib, marketed ... but does not keep the disease from returning if treatment ... drug,s radar and enable the disease to recur in most ... issue of Cancer Cell . The researchers ...
... An internationally recognized Virginia Commonwealth University physician has ... Award for his pioneering contributions that have advanced the ... past recipients who have made a remarkable impact on ... Foundation for Infectious Diseases awarded the honor to Richard ...
Cached Medicine News:Health News:Portable Health Care Records Now Available for Consumers 2Health News:'Health Care Reform Must be Abortion-Free,' says Supreme Knight 2Health News:Sagent Pharmaceuticals Announces Launch of First Two Oncolytic Products: Fludarabine Phosphate for Injection, USP and Epirubicin Hydrochloride Injection 2Health News:Finding key to cancer drug Gleevec's limitations 2Health News:National Foundation for Infectious Diseases honors VCU physician with Maxwell Finland Award for 2010 2Health News:National Foundation for Infectious Diseases honors VCU physician with Maxwell Finland Award for 2010 3
(Date:4/20/2015)... DIEGO , April 20, 2015  Halozyme ... company developing novel oncology and drug-delivery therapies, today ... the American Association for Cancer Research (AACR) annual ... results of its randomized Phase 2 study in ... annual meeting of the American Society of Clinical ...
(Date:4/20/2015)... PALO ALTO, Calif. , April 20, 2015 ... study demonstrate positive trends in the ability of ... slow the progression of amyotrophic lateral sclerosis (ALS, ... over a 6-month treatment period. While NP001,s slowing ... of the study was not statistically significant, clinically ...
(Date:4/20/2015)...  OpGen, Inc., a molecular testing and bioinformatics ... management team with the appointments of former Foundation ... Krenitsky , M.D. as president, and Timothy ... With more than 15 years ... biotechnology operations, including senior commercial and operational responsibilities ...
Breaking Medicine Technology:Halozyme Presents New Preclinical Data At The American Association for Cancer Research Annual Meeting, Announces Clinical Data Presentation At ASCO 2Halozyme Presents New Preclinical Data At The American Association for Cancer Research Annual Meeting, Announces Clinical Data Presentation At ASCO 3Halozyme Presents New Preclinical Data At The American Association for Cancer Research Annual Meeting, Announces Clinical Data Presentation At ASCO 4Halozyme Presents New Preclinical Data At The American Association for Cancer Research Annual Meeting, Announces Clinical Data Presentation At ASCO 5Published Phase 2 Results Demonstrate Neuraltus Pharmaceuticals' NP001 Potential Efficacy and Safety in ALS 2Published Phase 2 Results Demonstrate Neuraltus Pharmaceuticals' NP001 Potential Efficacy and Safety in ALS 3Published Phase 2 Results Demonstrate Neuraltus Pharmaceuticals' NP001 Potential Efficacy and Safety in ALS 4Published Phase 2 Results Demonstrate Neuraltus Pharmaceuticals' NP001 Potential Efficacy and Safety in ALS 5OpGen Appoints Industry Veterans Dr. Kevin Krenitsky as President and Timothy Dec as Interim Chief Financial Officer 2OpGen Appoints Industry Veterans Dr. Kevin Krenitsky as President and Timothy Dec as Interim Chief Financial Officer 3OpGen Appoints Industry Veterans Dr. Kevin Krenitsky as President and Timothy Dec as Interim Chief Financial Officer 4
Series I Small Joint Arthroscopy Hand Instruments feature small yet durable instruments specifically designed for small joint arthroscopy. They are available in a variety of low profile styles: strai...
Series I Small Joint Arthroscopy Hand Instruments feature small yet durable instruments specifically designed for small joint arthroscopy. They are available in a variety of low profile styles: strai...
Low-profile, hand-held instrument....
Low-profile, hand-held instrument....
Medicine Products: