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Researchers identify impact of rheumatoid arthritis and lupus on joint replacement surgery outcomes
Date:11/10/2012

Two new studies by researchers at Hospital for Special Surgery have overturned common beliefs about joint replacement in patients with lupus and rheumatoid arthritis (RA).

In one study, researchers demonstrated that RA patients who undergo a knee replacement can expect outcomes that are similar to individuals undergoing the operation for osteoarthritis. In the other, investigators showed that lupus patients undergoing joint replacement surgery experienced far fewer adverse events than previously thought. The news will be reported at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals, to be held Nov. 9-14, in Washington D.C.

Both studies relied on analyses of data from the HSS Total Joint Replacement Registry. Started in 2007, this prospective registry includes, among other things, data on all patients who seek care at HSS for knee and hip replacement surgery.

Lupus

Patients with lupus frequently need joint replacement surgery because they are treated with steroids that can lead to osteonecrosis (bone death caused by poor blood supply). Because little information is available about how lupus patients fare after surgery today, HSS researchers used the HSS Total Joint Replacement Registry to identify 101 lupus patients who underwent knee replacement (45) or hip replacement (56). They then matched each case to two similar patients who underwent the operation for osteoarthritis.

Patient pain and function had been assessed prior to surgery and two years after surgery using the Western Ontario and McMaster Universities Arthritis Index (WOMAC). WOMAC measures pain, stiffness, and functional limitation. It is one of the more widely used measuring tools for outcomes after total knee replacement. The investigators also used the Lower Extremity Activity Score (LEAS) to measure function. This score quantifies how much activity a person is capable of performing, ran
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Contact: Phyllis Fisher
phyllis.fisher@gmail.com
212-606-1724
Hospital for Special Surgery
Source:Eurekalert

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