Navigation Links
Researchers identify how binge drinking may drive heart disease
Date:11/26/2008

call for help from the immune system. Among other cell types, monocytes arrive with the goal of preventing infection, but end up causing inflammation that drives blood vessel blockage.

"Factors like binge-drinking have been linked to increased risk for heart disease, and the newer inflammatory model is beginning to explain how," said John Cullen, Ph.D., assistant professor in the Department of Surgery at the University of Rochester Medical Center. "One of our experiments found that acetaldehyde, at levels found in the blood after binge drinking, increased the number of monocytes that can adhere to cells lining blood vessels by 700 percent," said Cullen, who led the study.

Health psychologists argue that motivating people to stop binging depends upon their belief that it is harming them. Thus, the authors of the current study hope the results empower public health campaigns that discourage binge drinking.

Study Details

In between infections and injuries, dormant monocytes ride along with the bloodstream until they "realize" they are passing by part of a blood vessel wall close to the site of an injury or infection, or in the case of atherosclerosis, the site of cholesterol buildup. At this point, adhesion molecules on the monocyte surfaces unfold and grab onto key proteins on the surface of blood vessel wall cells, resisting the surrounding blood flow.

Whey they arrive on the scene, monocytes send out tethers, like anchors that snag the vessel wall. Once the monocyte swings close to the wall on its tether, it can then roll along the wall, getting stickier and sticker until it sticks in place permanently. Without this step, a major part of the immune component of atherosclerosis could not get underway.

In the current study, the team examined the effects of acetaldehyde on the ability of monocytes to home in on, tether to and roll along cells lining blood vessel walls. Researchers made cultures of the ce
'/>"/>

Contact: Greg Williams
Greg_Williams@urmc.rochester.edu
585-275-3676
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. UCSD researchers identify potential new drug target for chronic leukemia
2. USC researchers identify novel approach for suppressing prostate cancer development
3. Researchers identify new leprosy bacterium
4. UT Southwestern researchers develop new strategy for broad spectrum anti-viral drugs
5. Researchers discover strategy for predicting the immunity of vaccines
6. Ability to quit smoking may depend on ADHD symptoms, Columbia researchers find
7. Researchers ID Suite of Genes in Aging Process
8. Researchers: Ban on fast food TV advertising would reverse childhood obesity trends
9. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
10. Leeds researchers reshape the future of drug discovery
11. UNC researchers find clue to stopping breast-cancer metastasis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... (HealthDay News) -- Seniors are more easily distracted during ... study finds. "Almost any type of memory test ... of 25 on," study co-author Randi Martin, professor of ... release. However, Martin said, this study shows that ... older adults compared with younger adults. The study ...
(Date:7/25/2014)... 2014 As reported by Wood TV 8 ... (7/20), Michigan has seen a nearly 500-person increase in heroin ... count was 271 between 1999 and 2002, the toll increased ... that, like other states, drug users in Michigan have turned ... pills. He compared the price of both substances, noting that ...
(Date:7/25/2014)... Florida Hospital and MOSI officially announced a ... years to come and make a difference in the Tampa ... dollar check to provide the support needed to keep the ... to transform the IMAX Dome Theatre from film to a ... IMAX Dome Theatre in the state of Florida, and it ...
(Date:7/25/2014)... (PRWEB) July 25, 2014 Merrill ... of technology-enabled services for the financial, legal, healthcare ... virtual data room business, Merrill DataSite, has been ... presented by GrowthBusiness at the M&A Awards 2014 ... the achievements of entrepreneurs, management teams, advisors and ...
(Date:7/25/2014)... A new study conducted by the Hospital for ... of all children in the survey under the age of four ... 2,505 children during the years of 2011 and 2013. The children ... The final result was that about two out of every five ... were from lower-income families and were of East Asian heritage. , ...
Breaking Medicine News(10 mins):Health News:Distractions Seem More Troublesome With Age 2Health News:Rise in Heroin Use, Overdose Deaths in Michigan 2Health News:Florida Hospital Donates a Two Million Dollar Transformational Gift to the Museum of Science and Industry (MOSI) 2Health News:Florida Hospital Donates a Two Million Dollar Transformational Gift to the Museum of Science and Industry (MOSI) 3Health News:Florida Hospital Donates a Two Million Dollar Transformational Gift to the Museum of Science and Industry (MOSI) 4Health News:Merrill DataSite Recognized as “Technology Provider of the Year” by GrowthBusiness at the M&A Awards 2014 Event 2Health News:North York Dental Provides Services to Toronto Children in Light of Growing Demand 2Health News:North York Dental Provides Services to Toronto Children in Light of Growing Demand 3
... and, Marilyn Sargent of Success Design International, to offer a new course ... ... Jan. 22 The business of,life coaching takes another step forward with ... art and science of personal achievement. It is an art,because the way ...
... a protein that normally regulates muscle mass, and watch your ... idea to people with muscle-wasting diseases such as muscular dystrophy, ... weaker with age. Drugs that restrict the protein myostatin, which ... study, but not on the market, for some medical conditions. ...
... Ohio Consumers who pick up their prescription medications ... own safety in the name of convenience. , A ... with drive-through windows believe the extra distractions associated with ... even dispensing errors. , The surveyed pharmacists reported ...
... cancer who were treated with male hormone suppression therapy ... moderate to high levels of other illnesses did not ... January 23 issue of JAMA. , Several studies have ... therapy (AST) is combined with external beam radiation therapy ...
... exercise capacity reduces the risk of death in African-American ... the American Heart Association. , The government-supported Veterans Affairs ... to assess the link between fitness and mortality. , ... moderate levels of physical activity like brisk walking ...
... Marcy Leger Joins Agency as Executive Vice President, Managing ... Life, a leading healthcare,communications network, announced that Marcy Leger ... of Euro RSCG Life LM&P New,York, as a result ... to David Paragamian, Partner, President of Euro RSCG Life ...
Cached Medicine News:Health News:Spencer Institute Offers a Home-Training Course for Hemispheric Integration & Neuro-linguistics Coach Certification 2Health News:Drugs to bulk up muscles may make injuries more likely 2Health News:Drugs to bulk up muscles may make injuries more likely 3Health News:Pharmacists believe drive-through windows contribute to delays, errors 2Health News:Pharmacists believe drive-through windows contribute to delays, errors 3Health News:Pharmacists believe drive-through windows contribute to delays, errors 4Health News:Combination therapy improves survival for certain prostate cancer patients 2Health News:Daily exercise dramatically lowers men's death rates 2Health News:Daily exercise dramatically lowers men's death rates 3Health News:Euro RSCG Life LM&P Announces Growth of Leadership Team 2
(Date:7/25/2014)... 25, 2014 GrowBLOX Sciences, Inc. (OTCQB: GBLX) is ... Understanding ("MOU") with LaurelCo, LLC, an Illinois ... both cultivation and dispensary medical marijuana licenses in the state ... GBLX will acquire a 20% equity interest in LaurelCo, LLC ... growing chambers, as well as all technology related to ...
(Date:7/25/2014)... July 25, 2014  Acsis Inc., the market ... serialization solutions, has recently posted an article, ... current and future needs for companies, extended supply ... supply chain model no longer work today.  The ... the growth of mobile technology, machine to machine ...
(Date:7/25/2014)... , July 25, 2014 IBM (NYSE: ... healthcare sciences publisher, launched a library of mobile ... as cancer and heart disease. Healthcare providers using a ... to deliver better patient care. Mobile device ... relying on smartphones and tablets to access the information ...
Breaking Medicine Technology:GrowBLOX Sciences, Inc. Partners with LaurelCo, LLC to Obtain Licenses to Cultivate and Dispense Medical Marijuana in Illinois 2GrowBLOX Sciences, Inc. Partners with LaurelCo, LLC to Obtain Licenses to Cultivate and Dispense Medical Marijuana in Illinois 3Acsis Addresses Questions on the Modern Supply Chain 2Healthcare Sciences Publisher PLM and IBM Speed Access to Medical Information to Deliver Better Patient Care with Mobile 2Healthcare Sciences Publisher PLM and IBM Speed Access to Medical Information to Deliver Better Patient Care with Mobile 3Healthcare Sciences Publisher PLM and IBM Speed Access to Medical Information to Deliver Better Patient Care with Mobile 4
... rate for psychiatric medication spending has declined significantly, according ... Reuters (Healthcare) and the Substance Abuse and Mental Health ... ) The paper, which appears in the ... , underlines falling prices of psychiatric medications as one ...
... 2012 ThermoGenesis Corp. (NASDAQ: KOOL ), ... process and store adult stem cells, today provided updates ... (Res-Q) system, a point-of-care platform designed for the preparation ... at the Seventh International Conference on Cell Therapy for ...
Cached Medicine Technology:Psychiatric Medication Spending Growth Slows, According to New Thomson Reuters Research 2Psychiatric Medication Spending Growth Slows, According to New Thomson Reuters Research 3ThermoGenesis Provides Update on Res-Q® Clinical Evaluations at Leading Stem Cell Therapy Conference 2ThermoGenesis Provides Update on Res-Q® Clinical Evaluations at Leading Stem Cell Therapy Conference 3ThermoGenesis Provides Update on Res-Q® Clinical Evaluations at Leading Stem Cell Therapy Conference 4
... have a positive and negative inoculated well, ... these slides, perform QC and sample staining ... education and training programs by testing QC ... on one slide! KWIK-QC slides contain the ...
Microbiology QC Slides come with one or two droplets of an air-dried and methanol-fixed microorganism, or a single smear containing a designated microorganism population....
... Plate Capability The Equalizer 384 includes ... and equal tip spacing, choice of two software ... addition, this model allows you to evenly space ... accessing many gels and for use with 384 ...
Each slide contains a high yield of concentrated C. parvum oocysts within the positive control well. A negative control well is also included....
Medicine Products: