Navigation Links
Researchers identify how binge drinking may drive heart disease
Date:11/26/2008

As the holidays arrive, a group of researchers has identified the precise mechanisms by which binge drinking contributes to clogs in arteries that lead to heart attack and stroke, according to a study published today in the journal Atherosclerosis. The works adds to a growing body of evidence that drinking patterns matter as much, if not more, to risk for cardiovascular disease than the total amount consumed.

According to the National Institute on Alcohol Abuse and Alcoholism (NIAAA), going on a 'binge' means having five or more drinks for men, and four or more drinks for women, in two hours. Many studies suggest that an irregular pattern of heavy drinking brings about a two-fold increase in risk for a fatal heart attack, even as moderate drinking has been shown to reduce risk (the red wine effect). About 65 percent of Americans drink alcohol, with 15 percent reporting binge patterns in a national survey of problem drinkers.

Alcoholic beverages contain ethanol, which is mostly converted into acetaldehyde once in the human system at 'binge' levels, with the levels of acetaldehyde remaining high for many hours after the binge has ended. The current study clarified for the first time that binge levels of acetaldehyde cause an important type of immune cell, the monocyte, to become better able to stick to blood vessel walls, an important step in initiating atherosclerotic disease. Clarifying these mechanisms promises to empower the design of new treatments to counter the effects when combined with lifestyle change, researchers said.

In the past, experts believed that atherosclerosis developed when too much cholesterol clogged arteries with fatty deposits called plaques. When blood vessels became completely blocked, heart attacks occurred. Now most believe that the reaction of the body's immune system, more than the build-up itself, creates heart attack risk. Vessel walls mistake fatty deposits for intruders, akin to bacteria, and
'/>"/>

Contact: Greg Williams
Greg_Williams@urmc.rochester.edu
585-275-3676
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. UCSD researchers identify potential new drug target for chronic leukemia
2. USC researchers identify novel approach for suppressing prostate cancer development
3. Researchers identify new leprosy bacterium
4. UT Southwestern researchers develop new strategy for broad spectrum anti-viral drugs
5. Researchers discover strategy for predicting the immunity of vaccines
6. Ability to quit smoking may depend on ADHD symptoms, Columbia researchers find
7. Researchers ID Suite of Genes in Aging Process
8. Researchers: Ban on fast food TV advertising would reverse childhood obesity trends
9. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
10. Leeds researchers reshape the future of drug discovery
11. UNC researchers find clue to stopping breast-cancer metastasis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... (PRWEB) December 26, 2014 Recently, Dylan ... dresses, has excitedly released its collection of discounted prom ... to Percy, a senior spokesman of the company, the ... of this promotion is to expand the UK market. ... in several different colors, lengths, and styles: A-line strapless, ...
(Date:12/25/2014)... Recently, BellasDress has launched its Christmas Sale, ... has chosen their best-selling lace wedding dresses, vintage bridesmaid ... season. , Now, BellasDress.com features popular women’s dresses, ... discount prices. The business hopes everyone can have a ... , “All our elegant products are made with exquisite ...
(Date:12/25/2014)... Woodland Hills, California (PRWEB) December 25, 2014 ... in her home in Woodland Hills, California after an ... Harris passed away on Christmas Eve evening in her ... battle with aggressive metastatic breast cancer. ... International for over forty years, she pioneered and championed ...
(Date:12/25/2014)... 2014 Recently, LunaDress.co.uk has updated its blog to ... accessories. Now, all of the models at LunaDress.co.uk come with big ... lifts the wedding veil can turn out to be a most ... wedding veil can always bring surprise to a wedding. On the ... to choose veils for a big day . , Going ...
(Date:12/25/2014)... News) -- The risk of burns from fires and ... to be extra cautious, an expert says. "Between ... increase in patients coming in with burns," said Dr. ... Firefighters Burn Center of Stony Brook University Hospital in ... joy, but if not careful, could quickly turn tragic," ...
Breaking Medicine News(10 mins):Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:BellasDress.com’s Christmas Sale: Trendy Wedding Dresses With Big Discounts 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 3Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 4Health News:LunaDress Provides Professional Tips On Shopping Wedding And Prom Dresses 2Health News:Don't Let Burns Mar Your Holidays 2
... the truth about deadliness of Alzheimer,s, report says , , ... medical officials often fail to record severe dementia as a ... This finding not only points to a lack of knowledge ... can be a deadly illness, it suggests that deaths due ...
... mom and preemie baby , , ... to get one live person out of this situation, and we ... , , (Photo: http://www.newscom.com/cgi-bin/prnh/20081209/SF50878 ... of neonatology at Lucile Packard Children,s Hospital at Stanford , ...
... ANTONIO, Dec. 9 The Texas office of Oaks ... II, a 35,000,square-foot medical office building at 3603 Paesanos ... just east of the intersection of Loop 1604 and,Northwest ... divides ownership of the building among the tenants, equity,investors ...
... plans, executive benefits and investment consulting services, announced that its award-winning ... — at just the touch of a button. , ... ... These new resources are in addition to Spanish language enrollment ...
... Biggest rise in cases and deaths coming in developing ... -- By 2010, cancer will be the leading killer ... than AIDS, malaria and tuberculosis combined. , Unless new ... with cancer by 2030, and 17 million cancer deaths ...
... pediatricians, Fatema Meah, M.D. became a doctor because she loves ... when she entered private practice, she was frustrated with how ... billing issues. Two months ago, she and her partner ... to return her attention to her patients -- Allied Pediatrics ...
Cached Medicine News:Health News:Dementia Often Missed as Cause of Death 2Health News:Dementia Often Missed as Cause of Death 3Health News:It's A Merry Christmas for Baby John After Mother Michelle's Life-Saving Transplant 2Health News:It's A Merry Christmas for Baby John After Mother Michelle's Life-Saving Transplant 3Health News:It's A Merry Christmas for Baby John After Mother Michelle's Life-Saving Transplant 4Health News:It's A Merry Christmas for Baby John After Mother Michelle's Life-Saving Transplant 5Health News:Oaks Development Group Closes on Third San Antonio Project 2Health News:Oaks Development Group Closes on Third San Antonio Project 3Health News: Newport Introduces More Resources for Spanish Speaking Plan Participants 2Health News:Cancer to Surpass Heart Disease as World's Leading Killer 2Health News:Cancer to Surpass Heart Disease as World's Leading Killer 3Health News:Cancer to Surpass Heart Disease as World's Leading Killer 4Health News:'Mega' Pediatric Group Allows Doctors to Focus on Patient Care as the Business Side of Private Practice Becomes More Difficult to Sustain 2Health News:'Mega' Pediatric Group Allows Doctors to Focus on Patient Care as the Business Side of Private Practice Becomes More Difficult to Sustain 3
(Date:12/24/2014)... BUFFALO, N.Y. , Dec. 24, 2014 ... been dosed with KX2-361 at Roswell Park Cancer Institute. ... a small molecule drug that has shown potent inhibitory ... lines, including those that are resistant to Temozolomide (T98G), ... malignant glioma. In a well-established brain tumor mouse model, ...
(Date:12/24/2014)... 24, 2014  Conkwest, Inc., the Natural Killer ... Natural Killer (NK) cell-line platform, Neukoplast® (NK-92™) as ... Soon-Shiong , NantWorks founder, physician scientist and biotechnology ... purchase approximately $48 million of the Company,s Class ... he will be named Co-Chairman of the Conkwest ...
(Date:12/24/2014)... and LONDON , December 24, ... industry are expected to grow at an average rate ... of value and volume. Hip, knee and spine surgeries ... while in emerging economies they have a lower penetration. ... challenging the use of composites. Non-metallic orthopedic devices have ...
Breaking Medicine Technology:Kinex Pharmaceuticals Announces First Patient Dosed with KX2-361 in a Phase 1 Clinical Study 2Kinex Pharmaceuticals Announces First Patient Dosed with KX2-361 in a Phase 1 Clinical Study 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 2Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 4Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 5Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3
... Institute(R) Evidence Report Compares Effectiveness of CT Colonography ... The value of CT colonography, also called ... halting coverage of these procedures as a diagnostic ... Research findings from meta-analyses performed by ECRI Institute ...
... from MRI analysesROCHESTER, N.Y., March 12 VirtualScopics, ... provider of quantitative imaging for clinical trials, today ... company based in Laval, Quebec, has reached its ... for its cartilage repair device (BST-CarGel(R)) and will ...
Cached Medicine Technology:Virtual Colonoscopies Show Value for Some Patients, But Polyps Will Be Missed 2Virtual Colonoscopies Show Value for Some Patients, But Polyps Will Be Missed 3VirtualScopics' Quantitative Imaging Provides Primary Endpoint in Cartilage Repair Pivotal Clinical Trial 2VirtualScopics' Quantitative Imaging Provides Primary Endpoint in Cartilage Repair Pivotal Clinical Trial 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: