Navigation Links
Researchers identify gene set that shows which patients benefit from chemo after surgery
Date:9/7/2010

m and collaborators at NCIC Clinical Trials Group at Queen's University performed a genetic analysis of tumor tissue from 133 of the 482 patients from the JBR.10 study who had banked frozen tumor samples.

The Tsao team identified a set of 15 genes that, in 62 patients who did not receive chemotherapy after surgery, predicted which patients had aggressive cancers with high risk of recurrence and death (31 patients), and which had less aggressive disease and low risk of recurrence (31 patients).

They then applied the signature to 71 patients who were randomized to receive chemotherapy in the JBR.10 trial. Patients predicted to have aggressive disease experienced the greatest benefit from chemotherapy - with a 67 percent reduction in the risk of death - while chemotherapy did not reduce the risk of death in patients designated as low risk.

While a previous JBR.10 analysis showed that overall only patients with stage II disease benefited from chemotherapy after surgery, Dr. Tsao's study demonstrates that the 15 gene signature may identify patients with both stage I and II cancers who may benefit from post-operative chemotherapy.


'/>"/>

Contact: Jane Finlayson
jane.finlayson@uhn.on.ca
416-946-2846
University Health Network
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Researchers will test suicide prevention program in high schools
2. Mount Sinai researchers find new target to improve pain management
3. Non-invasive therapy significantly improves depression, UCLA researchers say
4. For the first time, researchers identify and isolate adult mammary stem cells in mice
5. UNH researchers develop improved tool for cycling fitness
6. Sodium MRI gives new insights into detecting osteoarthritis, NYU researchers find
7. Researchers urge reclassification of traumatic brain injury as chronic disease
8. Researchers closer to development of drug to prevent deadly immune response
9. Mayo researchers develop new laboratory cell lines to study treatment for ATC
10. Researchers zero in on protein that destroys HIV
11. 15 new US patents awarded this past year to NJIT researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/19/2013)... Maui'd Forever , Hawaii's premiere ... an effective and cost effective way to provide for ... up with Tom Barefoot’s Tours providing an activity agent ... Hawaii’s activities. , They have just released a new ... lowest prices on their Hawaii activities. , Maui’d ...
(Date:6/19/2013)... mantra of neurologists treating stroke victims has been "time equals ... quickly to receive a drug that dissolves the stroke-causing blood ... tissue is saved or lost. , But specific ... giving the intravenous drug known as a tissue plasminogen ... (clot-caused), stroke, the most common type of stroke. ...
(Date:6/19/2013)... (PRWEB) June 19, 2013 AquaPrint Solutions in ... Pub & Grub with a newly-designed Harley Davidson motorcycle gas ... of AquaPrint Solutions with an idea of taking a split ... the ages and transforming it into a work of art. ... Pub & Grub several toilet seats that had been dipped ...
(Date:6/19/2013)... Lake City, UT (PRWEB) June 19, 2013 ... expanded BRCA1 and BRCA2 testing service , providing ... Analysis is available individually, or as part of an ... to seventeen additional genes with known links to cancer ... CDK4, STK11, SMAD4, BMPR1A, CDH1, MET, FH, FLCN, PDGFRA, ...
(Date:6/19/2013)... When looking for ways to lose ... out how to lose belly fat and excess fat in ... thighs. Unnecessary and excess fat storage in these areas can ... Doc created their hCG diets to specially address ... weight loss aids with nutritious meal plans and education on ...
Breaking Medicine News(10 mins):Health News:Maui'd Forever Pleased to Offer Price Guarantee on Hawaii Activities 2Health News:Timely treatment after stroke is crucial, UCLA researchers report 2Health News:Timely treatment after stroke is crucial, UCLA researchers report 3Health News:AquaPrint Solutions Transforms Harley Davidson Gas Tank into a Work Of Art for Poopy’s Pub & Grub 2Health News:Ethigen Launches Next Generation (NGS) BRCA Testing With Expanded Hereditary Cancer Panel 2Health News:Ethigen Launches Next Generation (NGS) BRCA Testing With Expanded Hereditary Cancer Panel 3Health News:hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announce A New Four Phase Program that Allows Patients to Lose Belly Fat, Thigh Fat and Underarm Fat Easily 2
... The spirit of St. Patrick,s Day ... that, with 92 percent of some 10,000 retail locations reporting, ... in the event,s 27 year history.  As of today, the ... has raised more than $20 million to advance ...
... ... Now Serving. Now Serving will highlight the lives of four elderly Americans as they discover and ... ... blog site, My Apple Box , which catalogues the making of their Documentary film, Now ...
... ... tissue and bone damage , ... 17, 2010 -- According to a recent story in the New York Times , some ... metal artificial hips. New York personal injury attorney David Perecman comments about recent reports ...
... ... Ultimate Dental Health Makeover Contest and announces that they are increasing the amount of smile ... ... , the nation’s foremost voice in unbiased, expert advice on how to care for your ...
... ... help couples create stronger relationships. You can talk with an animated character - called an ... skills at calming an avatar who is playing the role of an irate partner. , ... New York, NY (PRWEB) March 17, 2010 -- ...
... ... ... that it will be expanding their eyeglasses online catalog by adding designer frames ... is adding designer Yoshi Ayaka to their collection of fashion frames to compliment their non-name ...
Cached Medicine News:Health News:27th Annual Shamrocks Against Dystrophy Sets $20 Million Fundraising Record 2Health News:27th Annual Shamrocks Against Dystrophy Sets $20 Million Fundraising Record 3Health News:27th Annual Shamrocks Against Dystrophy Sets $20 Million Fundraising Record 4Health News:Announcing the Launch of My Apple Box 2Health News:New York Personal Injury Attorney David Perecman Comments On Dangers Of ‘Metal On Metal' Hip Implants 2Health News:Dear Doctor Magazine Reveals Makeover Contest Winner's Results and Expands Contest to Include Additional Winners 2Health News:Dear Doctor Magazine Reveals Makeover Contest Winner's Results and Expands Contest to Include Additional Winners 3Health News:Avatar Meets Marriage Counseling; Take Imago Therapy for a Test Drive 2Health News:Avatar Meets Marriage Counseling; Take Imago Therapy for a Test Drive 3Health News:GlassesUSA.com Adds Designer Yoshi Ayaka Eyeglasses to Catalog 2
(Date:6/18/2013)... PROSPECT, Ill. , June 18, 2013 /PRNewswire-iReach/ ... of its new X3130 Appliance Inlet Module. The ... circuit breaker , combines a C14 appliance inlet ... one compact package.  This three-in-one device allows design ... their designs - cutting installation time by 66 ...
(Date:6/18/2013)... Mass. , June 18, 2013 ... the company was named Overall Performance Leader in Imaging ... Equipment & Infrastructure report. Philips also received Best in ... its imaging products: Ingenuity Core 128 Computed Tomography ... ultrasound and PageWriter TC70 cardiograph. The annual Best in ...
(Date:6/18/2013)... 18, 2013 Unilife Corporation ("Unilife" or "Company") ... and manufacturer of injectable drug delivery systems, today announced ... www.unilife.com . The new site includes additional products, videos, ... on a regular basis. Mr. Alan ... emerging global leader for injectable drug delivery systems, we ...
Breaking Medicine Technology:Three-in-One X3130 Appliance Inlet Module 2Philips Named 2013 Overall Performance Leader In Imaging Equipment By KLAS 2Unilife Launches New Corporate Website 2
... Inc. (Nasdaq: MSHL ), an oncology company ... cancer metabolism, announced today that it has filed a ... Exchange Commission for a rights offering to existing stockholders ... stock. The Company will announce further details regarding the ...
... Feb. 21, 2012  Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ... will present a company overview at Citi,s 2012 Global Health ... ET at the Waldorf Astoria in New York City. ... available on the "Investors & Media" section of the Company,s ...
Cached Medicine Technology:Marshall Edwards Announces Rights Offering to Stockholders 2Marshall Edwards Announces Rights Offering to Stockholders 3
... display of corneal layers: endothelium, ... epithelial layers. Accurate analysis of ... keratocytes, nerve fibres, basal & ... surgery and pathology: optical pachymetry, ...
The Ahmed Glaucoma Valve has been successfully demonstrated to work in all types of glaucoma cases, particularly neovascular, congenital and uvietic glaucoma....
Ahmed Glaucoma Valve with Pars Plana Clip....
Ahmed Glaucoma Valve Flexible Plate ....
Medicine Products: