Navigation Links
Researchers identify cell group key to Lyme disease arthritis
Date:12/3/2008

SAN DIEGO (December 3, 2008) A research team led by the La Jolla Institute for Allergy & Immunology and Albany Medical College has illuminated the important role of natural killer (NK) T cells in Lyme disease, demonstrating that the once little understood white blood cells are central to clearing the bacterial infection and reducing the intensity and duration of arthritis associated with Lyme disease.

"Our findings are that the NK T cells are critical to preventing the chronic inflammatory infection that causes Lyme arthritis and they participate in clearing the bacteria which cause it," said Mitchell Kronenberg, Ph.D., the La Jolla Institute's president & scientific director and co-senior author on the study, which used a mouse model of Lyme disease. Lyme disease is caused by Borrelia burgdorferi, a bacterium transmitted to humans by the bite of infected deer ticks. Typical symptoms include fever, headache, fatigue, and sometimes skin rashes. If left untreated, it can spread to the joints, the heart and the nervous system, and it can lead to serious health problems. Lyme disease currently is the most common vector (insect)-borne disease in the United States.

"What this study demonstrates is that NK T cells are an important part of our defense against Lyme disease," said Timothy J. Sellati, Ph.D., an associate professor at Albany Medical College and co-senior author on the study. "This offers the possibility that we can exploit that knowledge therapeutically and potentially develop immunological agents that can trigger more NK T cells to aide in fighting this disease." Sellati added that "NK T cells alone cannot clear Lyme disease, but are a key part of a collective immune defense."

The study's findings are outlined in a paper, "NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi," published this week in the online version of the journal Proceedings of the National Academy of Sciences.
'/>"/>

Contact: Bonnie Ward
contact@liai.org
619-303-3160
La Jolla Institute for Allergy and Immunology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/27/2015)... Vancouver, BC (PRWEB) February 27, 2015 ... exciting overnight deals for couples who wanted to spend ... with the opportunity to get a jump on Valentine’s ... meal and stay in one of their luxurious rooms. ... on February 13, inviting guests for a mouthwatering 3 ...
(Date:2/27/2015)... February 27, 2015 Glidewell Laboratories, ... the launch of its CloudPoint™ family ... digital production of monolithic zirconia crowns & bridges, ... of providing the CAD/CAM-produced restorations that doctors demand. ... through which cases can be scanned, managed and ...
(Date:2/27/2015)... (PRWEB) February 27, 2015 ... company that provides vascular, echocardiogram and NCV testing ... be the preferred diagnostic testing provider for young ... coeducational public liberal arts university in Milledgeville, Georgia. ... Wimbledon U collegiate division, include a ...
(Date:2/27/2015)... Over 440,000 patients die annually as a result of ... jet airplanes crashing each day. Now more than ever before, ... to do all they can to stay safe. , Through ... U.S. Surgeon General, discusses the importance of safer hospitals. “It’s ... safety issues to ensure that all our patients are in ...
(Date:2/27/2015)... 27, 2015 Lyophilization has important applications ... as a standard process to stabilize, store and increase ... molecules such as vaccines, antibodies, proteins, enzymes, hormones, ... structure. The global freeze drying market was valued at ... at $2,655.9 million by 2019 at a CAGR of ...
Breaking Medicine News(10 mins):Health News:Victorian Hotel Celebrated Valentine’s Day in 2015 With Unique Overnight Deal 2Health News:Glidewell Laboratories Announces Release of CloudPoint™ FastScan™ and FastDesign™ 2Health News:Glidewell Laboratories Announces Release of CloudPoint™ FastScan™ and FastDesign™ 3Health News:Georgia College Ensures Student-Athletes Are Heart Smart Team Strong; Teams up with Wimbledon Health Partners to Offer Diagnostic Testing 2Health News:Georgia College Ensures Student-Athletes Are Heart Smart Team Strong; Teams up with Wimbledon Health Partners to Offer Diagnostic Testing 3Health News:Dr. Richard Carmona, the 17th U.S. Surgeon General, and IntelliCentrics Raise Awareness in Mediaplanet’s “Patient Safety” Campaign 2Health News:Lyophilization Equipment Market worth $2,655.9 Million by 2019 - New Research Report by MarketsandMarkets 2Health News:Lyophilization Equipment Market worth $2,655.9 Million by 2019 - New Research Report by MarketsandMarkets 3
... , , Provides oral regime for ... SILVER SPRING, Md. , Jan. 29 The ... combination with Femara (letrozole) to treat hormone positive and HER2-positive ... is indicated. , (Logo: http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO ) , ...
... Over a two and half year period, beginning in 2005 ... office began reviewing marketing applications, a total of 60 new ... approved, according to a new article published online January 29 ... To provide an overview of recent regulatory actions ...
... Kentucky researcher is investigating respiratory weakness as a factor ... be testing new treatments that could improve long-term patient ... Supinski, professor and vice chair of research for the ... College of Medicine, was awarded a highly competitive, two-year, ...
... than blacks, researchers find , FRIDAY, Jan. 29 (HealthDay News) ... disease in the United States is more common in the ... as likely to develop the disease as blacks and Asians. ... 36 million Medicare recipients, are the first to take a ...
... ... 29   Following is the National Council on Disability,s monthly bulletin ... charge and at NCD,s award-winning Web site ( http://www.ncd.gov ), brings you ... the NCD listserv, go to http://listserv.access.gpo.gov , click on "Online mailing ...
... Va., Jan. 29 Care Net , ... support to pregnant women, was drawn into the Tebow Super ... Fox News.  Care Net President Melinda Delahoyde said ... pregnancy centers provide free services to 1.9 million people every ...
Cached Medicine News:Health News:FDA Expands Use of Approved Breast Cancer Drug 2Health News:FDA Expands Use of Approved Breast Cancer Drug 3Health News:Kentucky research looks at respiratory weakness in ICU morbidity 2Health News:Parkinson's More Common in Northeast, Midwest 2Health News:National Council on Disability Monthly Bulletin for January 2010 2Health News:National Council on Disability Monthly Bulletin for January 2010 3Health News:National Council on Disability Monthly Bulletin for January 2010 4Health News:National Council on Disability Monthly Bulletin for January 2010 5Health News:National Council on Disability Monthly Bulletin for January 2010 6Health News:National Council on Disability Monthly Bulletin for January 2010 7Health News:National Council on Disability Monthly Bulletin for January 2010 8Health News:National Council on Disability Monthly Bulletin for January 2010 9Health News:Care Net Calls Tebow Ad Opponents' Slam of Pregnancy Centers 'Nonsensical' 2
(Date:2/26/2015)... 26, 2015  AbbVie (NYSE: ABBV ... in its neuroscience and oncology development programs have ... American Academy of Neurology annual meeting in ... 18-25. The accepted abstracts feature results from studies ... investigational treatments in AbbVie,s pipeline. Presentations will include ...
(Date:2/26/2015)... Feb. 26, 2015  Mobility Ventures LLC, an AM ... Bank of America (NYSE: BAC ) that ... financing of the revolutionary MV-1 - - the world,s ... ground up to provide safe and comfortable transportation for ... their loan to purchase a new MV-1 vehicle at ...
(Date:2/26/2015)... -- Every year many millions of donations are obtained ... year after year doctors and the medical profession continue ... to determine the status of heart health in all ... though that technology is over 100 years old, ... (while most patients do not know) that EKG,s, in ...
Breaking Medicine Technology:AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 2AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 3AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 4AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 5AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 6AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 7Mobility Ventures and Bank of America Announce New Agreement to Simplify Retail Consumer Financing for MV-1 Universally Accessible Vehicle 2Mobility Ventures and Bank of America Announce New Agreement to Simplify Retail Consumer Financing for MV-1 Universally Accessible Vehicle 3National Heart Health Month In February 2
... LLC announced today that it has achieved the ... Products Certification for Health Information Line. The accreditation ... nurseline staffed by highly experienced, registered nurses that ... providing immediate clinical support for everyday health issues ...
... England, April 6, 2011 BioWa, Inc. (BioWa) ... they have entered into a license agreement to ... Technology platform for the development of antibody dependent ... OBT intends to use POTELLIGENT® Technology to develop, ...
Cached Medicine Technology:Alere Earns NCQA Health Information Products Certification for Health Information Line 2Oxford BioTherapeutics Licenses BioWa's POTELLIGENT® Technology for the Research and Development of its Therapeutic Antibodies in Cancer 2Oxford BioTherapeutics Licenses BioWa's POTELLIGENT® Technology for the Research and Development of its Therapeutic Antibodies in Cancer 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: