Navigation Links
Researchers from Boston University receive grant to develop improved virus detection system
Date:10/4/2011

(Boston) A team of researchers from Boston University's School of Medicine (BUSM) and College of Engineering (COE) have been awarded a five-year, $4.8 million National Institutes of Health (NIH) grant to develop a low-cost, multiplexed virus detection platform. Based on technologies developed with seed funding from Boston University's Photonics Center, the resulting diagnostic platform should be capable of rapidly detecting - at the point of care- viral pathogens such as Ebola, Lassa Fever and Marburg.

The actual testing of the virus detections platform with "hot" virus will take place at the University of Texas Medical Branch.

Led by principal investigator John Connor, PhD, an assistant professor of microbiology at BUSM, the research team also includes Selim nl, PhD, Hatice Altug, PhD, Catherine Klapperich, PhD and Mario Cabodi, PhD, all from the COE. Together their research groups will work to apply cutting-edge developments in engineering and physics to the task of finding and identifying infectious agents

"We brought together this interdisciplinary team in order to develop a breakthrough detector system that will allow a simple test for the presence of multiple viruses," said Connor. "To do that, we are working to negate the need for enzymes or fluorescent labels and are building nanoscale platforms that can look for multiple viruses at the same time," he added.

The team is working on two different detection technologies. For both technologies, the complete system will consist of a small "detector" chip containing integrated microfluidics. The microfluidics will allow samples to be drawn over the active sensing chip that will capture viruses.

The chip will then be analyzed in a "reader" that is capable of rapidly reading the detector chips and providing diagnostic information. The system should be able to simultaneously assess multiple possible infectious agents. The chips are smaller than a quarter, and the readers are expected to be the size of a breadbox, making them easily portable.

Early tests of the system will be carried out in Connor's laboratory which will use pseudo-viruses that will help with the development of the detection platforms. He will be utilizing a veterinary virus that will establish the sensitivity, reproducibility and the flexibility of the detection platforms. Following the initial development and validation of the detectors, the researchers will partner with Becton Dickinson (BD), a leading global medical technology company, to transform one of the virus diagnostic platforms into a working prototype. They will send the prototype for testing to the lab of Thomas Geisbert, PhD, from the University of Texas Medical Branch.

According to the researchers, the current limitations of conventional virus detection methods include expensive equipment, relatively long process times and require extensive training. "Under the new NIH grant, our goal is to produce a highly-sensitive, user-friendly, commercially-viable virus detection system that can be deployed at the point of care and detect viruses in about 30 minutes," explained nl.


'/>"/>

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center
Source:Eurekalert

Related medicine news :

1. Researchers review studies on CCSVI-MS link
2. Researchers call for more awareness of male breast cancer as cases rise
3. Researchers transform iPhone into high-quality medical imaging device
4. Fox Chase researchers identifiy more accurate treatment delivery for robotic radiosurgery system
5. Georgia Tech researchers receive 3 NSF Emerging Frontiers awards
6. Childrens National researchers make breakthrough in understanding white matter development
7. UH researchers explain hormonal role in glucose and fat metabolism
8. Researchers identify enzyme that regulates degradation of damaged proteins
9. UTHealth researchers train promotoras to combine mobile technology, cancer prevention messages
10. Researchers uncover gene associated with blood cancers
11. Boston researchers share in $10 million grant to study HIV and alcohol
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... April 28, 2017 , ... Beginning in 2017, Ridgecrest Herbals ... This begins with the popular ClearLungs Extra Strength formula. To ensure that the effectiveness ... in the following ways:, , Removal of the homeopathic element ...
(Date:4/28/2017)... NJ (PRWEB) , ... April 28, 2017 , ... Horizon ... has affirmed the company’s credit rating of “A” and its outlook as “stable.” At ... if capital reserves, which have fallen in recent years, dip below “capital adequacy” thresholds ...
(Date:4/28/2017)... ... , ... Getting enough sleep affects much more than energy – it also has mental and ... can compromise motor reaction time, which can increase the risk of having a car accident. ... tips from the NSF to help you sleep better and feel better:, ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... of the GlycoMark test throughout the Northeast U.S. , GlycoMark is the ... diabetes. The GlycoMark test provides a clinically proven one- to two-week measure of ...
(Date:4/28/2017)... Pass, OR (PRWEB) , ... April 28, 2017 ... ... Ijose, http://www.foodsthathealdaily.com , http://www.wiredlifesolutions.com , “Computers are everywhere and they’re ... Hour Power of Water, Global Climate Change and Your Health on Voice America ...
Breaking Medicine News(10 mins):
(Date:4/28/2017)...  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: ... fiscal second quarter ended March 31, 2017, and ... results and updated guidance reflect the contribution from ... completed on February 14, 2017.  For ... $0.51 per diluted share compared to $0.33 per ...
(Date:4/26/2017)... , April 26, 2017 Phoenix Marketing Solutions ... fifteenth year of fulfilling its mission of transforming science into ... highly scrutinized, Phoenix,s innovative approach supports ... community about the latest advances in science and medicine — ... was founded in 2002 by Tracy Doyle ...
(Date:4/25/2017)... April 25, 2017 Endo International plc (NASDAQ: ... 2017. Members of its senior management team will host a conference ... a.m. ET. The dial-in number to access the ... 509-7598, and the passcode is 6086379. Please dial in 10 minutes ... A replay of the call will be available from May ...
Breaking Medicine Technology: