Navigation Links
Researchers form new nerve cells &#8211 directly in the brain
Date:3/26/2013

The field of cell therapy, which aims to form new cells in the body in order to cure disease, has taken another important step in the development towards new treatments. A new report from researchers at Lund University in Sweden shows that it is possible to re-programme other cells to become nerve cells, directly in the brain.

Two years ago, researchers in Lund were the first in the world to re-programme human skin cells, known as fibroblasts, to dopamine-producing nerve cells without taking a detour via the stem cell stage. The research group has now gone a step further and shown that it is possible to re-programme both skin cells and support cells directly to nerve cells, in place in the brain.

"The findings are the first important evidence that it is possible to re-programme other cells to become nerve cells inside the brain", said Malin Parmar, research group leader and Reader in Neurobiology.

The researchers used genes designed to be activated or de-activated using a drug. The genes were inserted into two types of human cells: fibroblasts and glia cells support cells that are naturally present in the brain. Once the researchers had transplanted the cells into the brains of rats, the genes were activated using a drug in the animals' drinking water. The cells then began their transformation into nerve cells.

In a separate experiment on mice, where similar genes were injected into the mice's brains, the research group also succeeded in re-programming the mice's own glia cells to become nerve cells.

"The research findings have the potential to open the way for alternatives to cell transplants in the future, which would remove previous obstacles to research, such as the difficulty of getting the brain to accept foreign cells, and the risk of tumour development", said Malin Parmar.

All in all, the new technique of direct re-programming in the brain could open up new possibilities to more effectively repl
'/>"/>

Contact: Malin Parmar
Malin.Parmar@med.lu.se
46-462-220-620
Lund University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Moffitt Cancer Center researchers design small molecule to disrupt cancer-causing protein
2. UW researchers discover the brain origins of variation in pathological anxiety
3. Researchers decode biology of blood and iron disorders mapping out novel future therapies
4. Researchers developing antiviral drug to combat contagious norovirus
5. WSU researchers to study effect of fatigue on attention
6. Patient Wishes Should Guide End-of-Life Care, Researchers Say
7. Researchers new method may sharpen microscopic images
8. Researchers tackle physician challenge of correctly ordering laboratory tests
9. Moffitt Cancer Center researchers study use of dasatinib for patients with high-risk MDS
10. Brain Circuitry Yields Clue to Autism, Researchers Say
11. NIH-supported researchers identify new class of malaria compounds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... 29, 2014 The Law Offices of Michael ... of Hope, a non-profit organization providing grief camps for kids, ... anguish and suffering our clients experience from the death of ... support an organization like Stepping Stones of Hope, as they ... Stepping Stones of Hope also includes a monthly support group ...
(Date:7/29/2014)... have made an important advancement toward developing a ... disease, human granulocytic anaplasmosis (HGA). , During the ... rise in the incidence of human infections caused ... for a vaccine critical. Successful vaccine development hinges ... and the VCU team has identified three such ...
(Date:7/29/2014)... Most people want to turn back the clock on ... their appearance. There are anti aging microcurrent facials ... can help them to look their absolute best. Supreme ... anti-aging procedures that are noninvasive and they adding some body ... cellulite. To accommodate, they are also in the process ...
(Date:7/29/2014)... 29, 2014 The report, “Heat Transfer ... PAG & Glycol Fluids, & Others), by Application (Oil ... by Geography - Trends & Forecasts to 2019” defines ... an analysis and forecast of the global consumption in ... tables and 64 figures spread through 199 page sand ...
(Date:7/29/2014)... July 29, 2014 (HealthDay News) -- Successful negotiations may depend ... with wider faces may have an advantage, according to a ... broader face are more successful when negotiating for themselves than ... may not be an asset when negotiations require collaboration and ... we think about it or not. It,s not just the ...
Breaking Medicine News(10 mins):Health News:The Law Offices of Michael Cordova is Sponsoring Stepping Stones of Hope, a Non-Profit Organization Providing Grief Camps for Kids, Teens, Adults, and Families 2Health News:Researchers take steps toward development of a vaccine against tick-transmitted disease 2Health News:Researchers take steps toward development of a vaccine against tick-transmitted disease 3Health News:Supreme Skin Announces Plans for a Grand Re-opening for Their Noninvasive Anti Aging Microcurrent Face and Body Treatments In Asheville, NC 2Health News:Heat Transfer Fluids Market Expected to Grow 641,218.19 Tons by 2019 – New Report by MarketsandMarkets 2Health News:Heat Transfer Fluids Market Expected to Grow 641,218.19 Tons by 2019 – New Report by MarketsandMarkets 3Health News:Heat Transfer Fluids Market Expected to Grow 641,218.19 Tons by 2019 – New Report by MarketsandMarkets 4Health News:Wider Face May Give You an Edge in Negotiations 2
... administered externally , THURSDAY, July 9 (HealthDay News) -- ... thwart ear infections in children. , Antibiotics are typically ... recommended for children with recurrent ear infections. , "The ... the surgical procedure raise the need to develop different ...
... Universal Health Services, Inc. (NYSE: UHS ) ... a cash dividend of $0.08 per share on September 15, ... , , Universal Health Services, Inc. is one of ... care and behavioral health hospitals, and ambulatory centers nationwide and ...
... With healthcare reform a high priority on ... of Health Integrated, a leading provider of Health Management Solutions, ... offer solutions to drive down costs while also improving healthcare ... http://www.newscom.com/cgi-bin/prnh/20090709/FL43703LOGO ) , , "Despite ...
... In a rebuke to the status quo in a ... for Congress to modernize transportation policy so the Port has ... to make goods movement sustainable for local communities and workers. ... forward on a resolution at their July 21st board meeting ...
... 9 Go Healthy, Inc. (Pink Sheets: GOHE) announced today ... strategically located bottling facilities. Go Healthy plans to bottle ... attention of these bottlers. They have proposed various forms ... , , Charlie Caudle, CEO of Go Healthy, ...
... Perceptive Informatics, a leading eClinical solutions provider and ... PRXL ), today announced that it has ... analysis of medical images for central nervous system ... alliance with Biospective, Inc. Through this alliance, Perceptive ...
Cached Medicine News:Health News:Vaccine May Someday Thwart Ear Infections 2Health News:Health Plans Continue to Select Health Integrated to Improve Member Health, Reduce Costs 2Health News:Health Plans Continue to Select Health Integrated to Improve Member Health, Reduce Costs 3Health News:Health Plans Continue to Select Health Integrated to Improve Member Health, Reduce Costs 4Health News:Health Plans Continue to Select Health Integrated to Improve Member Health, Reduce Costs 5Health News:Oakland Port Commission Seeks Resolution to Allow Local Officials Real Power to Clean Up Diesel Truck Pollution; Improve Security, Safety 2Health News:Oakland Port Commission Seeks Resolution to Allow Local Officials Real Power to Clean Up Diesel Truck Pollution; Improve Security, Safety 3Health News:Oakland Port Commission Seeks Resolution to Allow Local Officials Real Power to Clean Up Diesel Truck Pollution; Improve Security, Safety 4Health News:Go Healthy Announces Negotiations With Bottling Facilities 2Health News:Perceptive Informatics Enhances CNS and Oncology Medical Image Processing and Analysis Capabilities Through Alliance With Biospective 2Health News:Perceptive Informatics Enhances CNS and Oncology Medical Image Processing and Analysis Capabilities Through Alliance With Biospective 3Health News:Perceptive Informatics Enhances CNS and Oncology Medical Image Processing and Analysis Capabilities Through Alliance With Biospective 4Health News:Perceptive Informatics Enhances CNS and Oncology Medical Image Processing and Analysis Capabilities Through Alliance With Biospective 5
(Date:7/29/2014)...  Instrumentation Laboratory (IL) today announced the launch of its ... is part of a comprehensive rebranding effort by Werfen, the ... Boston, MA , in 1959, IL has been part ... companies in the group include Inova Diagnostics ( San ... Spain ).  Like IL, these three companies are focused ...
(Date:7/29/2014)... WESTFORD, Mass., July 29, 2014 Cynosure, ... and markets laser- and light-based aesthetic treatment systems for ... months ended June 30, 2014. Second-quarter 2014 financial results ... completed on June 24, 2013. ... revenues increased 45% to $72.6 million , Non-GAAP ...
(Date:7/29/2014)... 2014  Ambit Biosciences (Nasdaq: AMBI ), a ... targeting unmet needs in oncology, autoimmune and inflammatory disease, ... after closing of the NASDAQ Global Market on Tuesday, ... hosted by Michael Martino , president and CEO, ... on the same day at 5:00 pm EDT (2:00 ...
Breaking Medicine Technology:Instrumentation Laboratory Unveils New Corporate Brand 2Instrumentation Laboratory Unveils New Corporate Brand 3Cynosure Reports Second-Quarter 2014 Financial Results 2Cynosure Reports Second-Quarter 2014 Financial Results 3Cynosure Reports Second-Quarter 2014 Financial Results 4Cynosure Reports Second-Quarter 2014 Financial Results 5Cynosure Reports Second-Quarter 2014 Financial Results 6Cynosure Reports Second-Quarter 2014 Financial Results 7Cynosure Reports Second-Quarter 2014 Financial Results 8Cynosure Reports Second-Quarter 2014 Financial Results 9Cynosure Reports Second-Quarter 2014 Financial Results 10Cynosure Reports Second-Quarter 2014 Financial Results 11Cynosure Reports Second-Quarter 2014 Financial Results 12Ambit Biosciences To Announce Second Quarter 2014 Financial Results 2
... The New England Journal of Medicine today released a study entitled, ... discussed in the report were brought by Phillips & Cohen LLP, a law ... Phillips & Cohen has specialized in representing whistleblowers for more than 20 years. ... Comments from Erika ...
... , May 12 The U.S. Food and Drug Administration is ... Itch Stopping Gel, an over-the-counter (OTC) product that should only be used on ... (Logo: http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO ... The FDA has received reports ...
Cached Medicine Technology:Whistleblower Lawyers Comment on New England Journal of Medicine Study 2Whistleblower Lawyers Comment on New England Journal of Medicine Study 3FDA: Serious Side Effects from Swallowing Topical Benadryl Product 2FDA: Serious Side Effects from Swallowing Topical Benadryl Product 3
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
We offer small and large pre-gelled Surface Electrodes suitable for EGG or EMG recordings. Surface Electrodes, Skin Preparation and Conductive Cream complete the setup for a EGG study and are essenti...
Medicine Products: