Navigation Links
Researchers find that inhibiting microRNAs may help prevent degenerative eye disorders
Date:6/6/2011

he process becomes imbalanced, however, increased angiogenesis can lead to a variety of debilitating conditions.

Previous treatments for degenerative eye disorders have focused on inhibiting vascular endothelial growth factor (VEGF), a secreted protein that stimulates blood vessel formation. VEGF has been known to be a contributing factor in vascular disease in the retina of the eye.

Anti-VEGF drugs, which are injected into the eyeball, have been used to give patients some improvement in vision. These drugs, however, have limited effectiveness in treating some forms of neovascular AMD, and also have potential side effects.

Dr. Wang said further research may show that other microRNAs might also be involved, and that targeting multiple pathways may provide benefits in the treatment of these diseases.

"We want to see if a combination of microRNAs and angiogenetic drugs have a synergetic effect on the progression of macular degeneration," Dr. Wang said.

Dr. Eric Olson, chairman of molecular biology, was the study's other co-senior author. Other UT Southwestern researchers involved were Dr. Rafael Ufret-Vincenty, assistant professor of ophthalmology, Dr. Qinbo Zhou, postdoctoral fellow and lead author; Rachel Gallagher, research technician; and Dr. Xinyu Li, a visiting professor.


'/>"/>

Contact: Robin Russell
robin.russell@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... prevent the depletion of self-control, according to research published ... Association for Psychological Science. , Self-control can be difficult ... attention on a boring textbook are hard things to ... difficulty: Exerting self-control for a long period seems to ... tasks. , "It is as if self-control is a ...
(Date:4/22/2014)... Government and industry leaders visited the New Jersey ... President Joel S. Bloom for the launch of ... corporation that provides a new model for business ... higher education assets and investment. U.S. Senator Cory ... CEO Joe Taylor, New Jersey Lieutenant Governor Kim ...
(Date:4/22/2014)... at UT Southwestern Medical Center are making breakthroughs that ... A team of physician-scientists at UT Southwestern has ... with natural anti-depressant properties) works inside the brain. Simultaneously, ... depression in the form of a neuroprotective drug known ... in April,s issue of Molecular Psychiatry, is ...
(Date:4/22/2014)... 2014) The International Communication Association will hold ... Washington. The theme of the 2014 conference will ... networked and digital society. , Featuring over 2,300 ... 2,200 Communication scholars representing over 40 countries, the ... conference in the world. This year,s conference features ...
(Date:4/22/2014)... Sophia Antipolis, 22 April 2014. The latest scientific advances ... at Heart Failure 2014, the main annual meeting of ... of Cardiology (ESC). Journalists will also hear breaking news ... on Acute Heart Failure, which is part of the ... May in Athens, Greece, at the Megaron Athens International ...
Breaking Medicine News(10 mins):Health News:ADHD drug may help preserve our self-control resources 2Health News:Government and industry leaders herald launch of NJIT's New Jersey Innovation Institute 2Health News:Depressed? Researchers identify new anti-depressant mechanisms, therapeutic approaches 2Health News:Depressed? Researchers identify new anti-depressant mechanisms, therapeutic approaches 3Health News:International Communication Association to hold Annual Conference in Seattle, Washington 2Health News:The world's largest heart failure congress 2Health News:The world's largest heart failure congress 3
... adolescent psychiatrists, researchers from the University of Copenhagen have just ... been done so far on the significance of diet for ... there are potential benefits in changing the diets of children ... still lacking. The comprehensive report covers the scientific literature ...
... LANSING, Mich. The rate of workplace deaths in Michigan ... job compared with 145 in 2010, according to an annual ... the most deaths at 24, while the agriculture industry had ... Assessment and Control Evaluation program, or MIFACE. The ...
... Steven Reinberg HealthDay Reporter , MONDAY, April ... percent worldwide between 2000 and 2010, but progress is ... officials reported Monday. "This is one of the ... said Anthony Lake, executive director of the United Nations ...
... many people with gastroesophageal reflux disease or GERD, acid reflux ... heartburn and regurgitation of food or sour liquid characteristic of ... condition commonly found in people with GERD, acid control may ... bile. A new study published in the ...
... the treatment and survival rate of elderly patients diagnosed ... awarded almost 2million by the National Institute of Health ... effectively as younger women. Professor Malcolm Reed and ... University of Sheffield are leading the ground-breaking programme - ...
... Crews, assistant professor of mechanical engineering at Louisiana Tech ... has been awarded an Early Career Development grant by ... Gradient Microflow Calorimetry using Anisotropic Temperature Sensors." The ... of his research program and also integrate his research ...
Cached Medicine News:Health News:Dietary changes help some children with ADHD 2Health News:On-the-job deaths steady in Michigan; Number of burn injuries underreported 2Health News:Measles Deaths Falling Worldwide 2Health News:Measles Deaths Falling Worldwide 3Health News:Bile - not acid - is bad guy in triggering precancerous condition associated with reflux disease 2Health News:Bile - not acid - is bad guy in triggering precancerous condition associated with reflux disease 3Health News:Bridging the gap in treatment for older women with breast cancer 2Health News:Louisiana Tech University professor earns NSF Early Career Development grant 2
(Date:1/15/2014)... , Jan. 15, 2014 Reportlinker.com ... is available in its catalogue: ... – Worldwide Analysis http://www.reportlinker.com/p01957812/Insulin-Pump-Market--Forecast-–-Worldwide-Analysis.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Equipment_and_Supply ... Analysis Insulin Pumps ...
(Date:1/15/2014)... Quebec , Jan. 15, 2014  Valeant Pharmaceuticals International, ... announced that the applicable waiting period under the Hart-Scott-Rodino ... the previously announced tender offer by its indirect wholly-owned ... outstanding shares of common stock of Solta Medical, Inc. ...
(Date:1/15/2014)... , Jan. 15, 2014 ... research report is available in its ... Markets and Technologies for Advanced Drug ... of Administration ...
Breaking Medicine Technology:Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 16
... Drug Discovery Support Program, HAMBURG, Germany ... AG (Frankfurt Stock Exchange: EVT) announced today ... (Osaka, Japan) signed a new drug,discovery agreement ... The collaboration applies Evotec,s proprietary fragment-based drug,discovery ...
... 26 Poniard,Pharmaceuticals, Inc. (Nasdaq: PARD ), ... with W. C. Heraeus GmbH for the,commercial manufacture ... is investigating picoplatin, the Company,s lead,product candidate, in ... trial in small cell lung cancer, and is ...
Cached Medicine Technology:Ono Enters into a New Fragment-Based Drug Discovery Agreement with Evotec 2Ono Enters into a New Fragment-Based Drug Discovery Agreement with Evotec 3Poniard Pharmaceuticals Announces Commercial Manufacturing Agreement With W. C. Heraeus GmbH for Picoplatin 2Poniard Pharmaceuticals Announces Commercial Manufacturing Agreement With W. C. Heraeus GmbH for Picoplatin 3
... Special Protective Apron is made to ... a sterile gown. Uniquely it can ... field. Reaching through the back of ... released, and the protective apron will ...
... a 2 adjustable belt buckle. You adjust once ... Apron off your shoulders. And now theres our ... female anatomy. ,For additional back support try one ... pressure on the vertebrae and help "lift the ...
... is an extremely modular and flexible system that can ... patient is in the comfort of their home. The ... in a lightweight pouch. The alkaline batteries are in ... used is a standard flash memory card. EEG data ...
... Building on over 20 years ... handling platforms for the Life Sciences, ... more flexibility and possibilities for expansion ... the new easy-to-use software, Freedom EVOware, ...
Medicine Products: